Patents by Inventor Ralph H. Schwall

Ralph H. Schwall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for treating vascular stenosis
    Patent number: 6133234
    Abstract: Methods for treating vascular stenosis using hepatocyte growth factor ("HGF") are provided. In the methods, HGF can be administered to enhance re-surfacing of blood vessels damaged or traumatized, for instance, by vascular surgery or angioplasty. Articles of manufacture and kits containing HGF are also provided.
    Type: Grant
    Filed: March 31, 1998
    Date of Patent: October 17, 2000
    Assignees: Genentech, Inc., The General Hospital Corporation
    Inventors: Stuart Bunting, Herman K. Gold, Robert C. Leinbach, Ralph H. Schwall
  • Angiogenesis using hepatocyte growth factor
    Patent number: 6133231
    Abstract: Methods for enhancing angiogenesis in a mammal using hepatocyte growth factor ("HGF") are provided. In the methods, HGF can be administered to mammals suffering from, for instance, vascular insufficiency or arterial occlusive disease. Articles of manufacture and kits containing HGF are also provided.
    Type: Grant
    Filed: May 22, 1998
    Date of Patent: October 17, 2000
    Assignees: Genentech, Inc., St. Elizabeth's Medical Center of Boston, Inc.
    Inventors: Napoleone Ferrara, Jeffrey M. Isner, Ralph H. Schwall
  • Hepatocyte growth factor receptor agonists and uses thereof
    Patent number: 6099841
    Abstract: Hepatocyte growth factor (HGF) receptor agonists are provided. The HGF receptor agonists include HGF receptor antibodies and fragments thereof. The HGF receptor agonists can be employed to substantially enhance HGF receptor activation. The HGF receptor agonists may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treatment and diagnosis using the HGF receptor agonists are also provided.
    Type: Grant
    Filed: June 27, 1997
    Date of Patent: August 8, 2000
    Assignee: Genentech, Inc.
    Inventors: Kenneth J. Hillan, Ralph H. Schwall, Kelly H. Tabor
  • Hepatocyte growth factor receptor antagonist antibodies and uses thereof
    Patent number: 5686292
    Abstract: Hepatocyte growth factor (HGF) receptor antagonists are provided. The HGF receptor antagonists include HGF receptor antibodies and fragments thereof. The HGF receptor antagonists can be employed to block binding of HGF to HGF receptors or substantially inhibit HGF receptor activation. The HGF receptor antagonists may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treating cancer using the HGF receptor antagonists are also provided.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: November 11, 1997
    Assignee: Genentech, Inc.
    Inventors: Ralph H. Schwall, Kelly Helen Tabor
  • Nucleic acids encoding hepatocyte growth factor receptor antagonist antibodies
    Patent number: 5646036
    Abstract: Hepatocyte growth factor (HGF) receptor antagonists are provided. The HGF receptor antagonists include HGF receptor antibodies and fragments thereof. The HGF receptor antagonists can be employed to block binding of HGF to HGF receptors or substantially inhibit HGF receptor activation. The HGF receptor antagonists may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treating cancer using the HGF receptor antagonists are also provided.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: July 8, 1997
    Assignee: Genentech, Inc.
    Inventors: Ralph H. Schwall, Kelly Helen Tabor