Patents by Inventor Ralph Hall

Ralph Hall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • System and method for stimulating the heart in combination with cardiac rhythm management pharmaceuticals
    Patent number: 10549102
    Abstract: Sensors are applied to the heart and sensor data is supplied to a rules engine. The rules engine applies rules that reflect a CRM pharmaceutical regime of the patient to the sensor data to determine whether an electrical waveform should be applied to the heart. When electrical stimulation is warranted, the drug “awareness” rules are used by the rules engine to instruct a multi-phase cardiac stimulus generator to generate an electrical waveform that improves the performance of the drugs administered to the patient, allow the patient to be administered a lower dose of a particular drug, and/or reduce or eliminate side effects from the drugs.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: February 4, 2020
    Assignee: MR3 MEDICAL, LLC
    Inventors: Morton M. Mower, Ralph Hall
  • System and method for stimulating the heart in combination with cardiac rhythm management pharmaceuticals
    Patent number: 9943692
    Abstract: Sensors are applied to the heart and sensor data is supplied to a rules engine. The rules engine applies rules that reflect a CRM pharmaceutical regime of the patient to the sensor data to determine whether an electrical waveform should be applied to the heart. When electrical stimulation is warranted, the drug “awareness” rules are used by the rules engine to instruct a multi-phase cardiac stimulus generator to generate an electrical waveform that improves the performance of the drugs administered to the patient, allow the patient to be administered a lower dose of a particular drug, and/or reduce or eliminate side effects from the drugs.
    Type: Grant
    Filed: April 7, 2016
    Date of Patent: April 17, 2018
    Assignee: MR3 MEDICAL, LLC
    Inventors: Morton M. Mower, Ralph Hall
  • System and method for stimulating the heart via the vagus nerve
    Patent number: 9616236
    Abstract: A rules engine acquires sensor data from sensors applied to the heart to determine the presence of a rapid heartbeat. The rules engine applies rules to the sensor data to determine whether to deliver an electrical waveform to a vagus nerve. The rules engine further determines whether an electrical waveform should be applied to the heart and, if so, the type of electrical waveform.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: April 11, 2017
    Assignee: MR3 MEDICAL, LLC.
    Inventors: Morton M. Mower, Ralph Hall
  • System and method for stimulating the heart using sub-threshold biphasic stimulation
    Patent number: 9610446
    Abstract: A rules engine acquires sensor data from sensors applied to the heart and determines whether an electrical waveform should be applied to the heart and, if so, the type of electrical waveform. A multiphase cardiac stimulus generator generates waveforms in response to the rules engine. The electrical waveform is applied to one or more electrodes implanted in or on the heart.
    Type: Grant
    Filed: February 8, 2016
    Date of Patent: April 4, 2017
    Assignee: MR3 MEDICAL, LLC
    Inventors: Morton M. Mower, Ralph Hall
  • SYSTEM AND METHOD FOR STIMULATING THE HEART IN COMBINATION WITH CARDIAC RHYTHM MANAGEMENT PHARMACEUTICALS
    Publication number: 20170080224
    Abstract: Sensors are applied to the heart and sensor data is supplied to a rules engine. The rules engine applies rules that reflect a CRM pharmaceutical regime of the patient to the sensor data to determine whether an electrical waveform should be applied to the heart. When electrical stimulation is warranted, the drug “awareness” rules are used by the rules engine to instruct a multi-phase cardiac stimulus generator to generate an electrical waveform that improves the performance of the drugs administered to the patient, allow the patient to be administered a lower dose of a particular drug, and/or reduce or eliminate side effects from the drugs.
    Type: Application
    Filed: December 2, 2016
    Publication date: March 23, 2017
    Applicant: MR3 MEDICAL, LLC
    Inventors: Morton M. MOWER, Ralph HALL
  • System and method for stimulating the heart in combination with cardiac rhythm management pharmaceuticals
    Patent number: 9566445
    Abstract: Sensors are applied to the heart and sensor data is supplied to a rules engine. The rules engine applies rules that reflect a CRM pharmaceutical regime of the patient to the sensor data to determine whether an electrical waveform should be applied to the heart. When electrical stimulation is warranted, the drug “awareness” rules are used by the rules engine to instruct a multi-phase cardiac stimulus generator to generate an electrical waveform that improves the performance of the drugs administered to the patient, allow the patient to be administered a lower dose of a particular drug, and/or reduce or eliminate side effects from the drugs.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: February 14, 2017
    Assignee: MR3 MEDICAL, LLC
    Inventors: Morton M. Mower, Ralph Hall
  • System and method for stimulating the heart via storage of multi-waveforms in a cardiac stimulation device
    Patent number: 9566446
    Abstract: A rules engine acquires sensor data from sensors applied to the heart and determines whether an electrical waveform should be applied to the heart and, if so, the type of electrical waveform. A multi-phase cardiac stimulus generator generates waveforms in response to the rules engine from waveform data stored in a memory. The electrical waveform is applied to one or more electrodes implanted in or on the heart.
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: February 14, 2017
    Assignee: MR3 MEDICAL, LLC
    Inventors: Morton M. Mower, Ralph Hall
  • System and method for stimulating the heart using sub-threshold biphasic stimulation
    Patent number: 9446247
    Abstract: A rules engine acquires sensor data from sensors applied to the heart and determines whether an electrical waveform should be applied to the heart and, if so, the type of electrical waveform. A multiphase cardiac stimulus generator generates waveforms in response to the rules engine. The electrical waveform is applied to one or more electrodes implanted in or on the heart.
    Type: Grant
    Filed: May 21, 2014
    Date of Patent: September 20, 2016
    Assignee: MR3 MEDICAL, LLC
    Inventors: Morton M. Mower, Ralph Hall
  • 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy
    Patent number: 8058282
    Abstract: Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Grant
    Filed: August 19, 2010
    Date of Patent: November 15, 2011
    Assignee: GlaxoSmithKline LLC
    Inventors: Jerry L. Adams, Jeffrey C. Boehm, Ralph Hall, Qi Jin, Jiri Kasparec, Domingos J. Silva, John J. Taggart
  • 2,4,8-TRISUBSTITUTED-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE COMPOUNDS AND COMPOSITIONS FOR USE IN THERAPY
    Publication number: 20110046109
    Abstract: Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: August 19, 2010
    Publication date: February 24, 2011
    Applicant: GLAXOSMITHKLINE LLC
    Inventors: Jerry L. Adams, Jeffrey C. Boehm, Ralph Hall, Qi Jin, Jiri Kasparec, Domingos J. Silva, John J. Taggart
  • NOVEL COMPOUNDS
    Publication number: 20110009625
    Abstract: Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: September 16, 2010
    Publication date: January 13, 2011
    Applicant: GLAXOSMITHKLINE LLC
    Inventors: Jerry L. Adams, Jeffrey C. Boehm, Ralph Hall, Qi Jin, Jiri Kasparec, Domingos J. Silva, John J. Taggart
  • 2,4,5-Trisubstituted pyrimidine compounds
    Patent number: 7759486
    Abstract: Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Grant
    Filed: August 16, 2007
    Date of Patent: July 20, 2010
    Assignee: GlaxoSmithKline LLC
    Inventors: Jerry L. Adams, Jeffrey C. Boehm, Ralph Hall, Qi Jin, Jiri Kasparec, Domingos J. Silva, John J. Taggart
  • NOVEL COMPOUNDS
    Publication number: 20090105478
    Abstract: Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: August 16, 2007
    Publication date: April 23, 2009
    Inventors: JERRY L. ADAMS, JEFFREY C. BOEHM, RALPH HALL, QI JIN, JIRI KASPAREC, DOMINGOS J. SILVA, JOHN J. TAGGART
  • NOVEL COMPOUNDS
    Publication number: 20080033170
    Abstract: Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: August 16, 2007
    Publication date: February 7, 2008
    Inventors: Jerry Adams, Jeffrey Boehm, Ralph Hall, Qi Jin, Jiri Kasparec, Domingos Silva, John Taggart
  • NOVEL COMPOUNDS
    Publication number: 20080032969
    Abstract: Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: August 16, 2007
    Publication date: February 7, 2008
    Inventors: Jerry Adams, Jefrrey Boehm, Ralph Hall, Qi Jin, Jiri Kasparec, Domingos Silva, John Taggart
  • 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds
    Patent number: 7323472
    Abstract: The present invention is directed to the novel use of a CSBP/p38 inhibitor for the treatment, including prophylaxis of inflammation enhanced cough in a mammal in need thereof.
    Type: Grant
    Filed: October 23, 2001
    Date of Patent: January 29, 2008
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Jeffrey C. Boehm, Ralph Hall, Qi Jin, Jiri Kasparec, Domingos J. Silva, John J. Taggart
  • 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds
    Patent number: 7314881
    Abstract: Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Grant
    Filed: April 6, 2004
    Date of Patent: January 1, 2008
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Jeffrey C. Boehm, Ralph Hall, Qi Jin, Jiri Kasparec, Domingos J. Silva, John J. Taggart
  • 4-amino substituted-6-aryl/heteroaryl substituted-2-methylsulfanyl-pyrimidine-5-carbaldehyde intermediates
    Patent number: 7314934
    Abstract: Novel substituted 2,4,8-trisubstituted-8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Grant
    Filed: August 19, 2003
    Date of Patent: January 1, 2008
    Assignee: SmithKline Beecham Corporation
    Inventors: Jerry L. Adams, Jeffrey C. Boehm, Ralph Hall, Qi Jin, Jiri Kasparec, Domingos J. Silva, John J. Taggart
  • 1,5-DISUBSTITUTED-3,4-DIHYDRO-1H-PYRIMIDO[4,5-D]PYRIMIDIN-2-ONE COMPOUNDS AND THEIR USE IN TREATING CSBP/P38 KINASE MEDIATED DISEASES
    Publication number: 20070238743
    Abstract: Novel substituted pyrimido[4,5-d]pyrimidin-2-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: December 20, 2006
    Publication date: October 11, 2007
    Inventors: Jerry Adams, Jeffrey Boehm, John Taggart, Ralph Hall
  • 1,5-DISUBSTITUTED-3,4-DIHYDRO-1H-PYRIMIDO[4,5-D]PYRIMIDIN-2-ONE COMPOUNDS AND THEIR USE IN TREATING CSBP/P38 KINASE MEDIATED DISEASES
    Publication number: 20070167467
    Abstract: Novel substituted pyrimido[4,5-d]pyrimidin-2-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.
    Type: Application
    Filed: December 20, 2006
    Publication date: July 19, 2007
    Inventors: Jerry Adams, Jeffrey Boehm, John Taggart, Ralph Hall