Abstract: A compact wearable modular multifunctional inhalation device of the present invention. In the illustrative embodiment, the device includes a housing with at least one port; a removable cartridge module adapted to seat within the housing, the cartridge including: a source of inhalant mounted within the cartridge for providing inhalant into the port and a heating element mounted within the cartridge for heating the inhalant; a removable modular electronic circuit adapted to seat within the housing to provide electrical current to the heating element; and a mechanism coupled to the housing for wearing the device. The electronic circuit may include a processor and memory. A removable modular electronic display is adapted to seat within the housing and connect electrically with the circuit. Software is stored in the memory for execution by the processor for activating the heating element. The software includes code for monitoring the status of the inhalant and/or the source of electrical potential.

Abstract: In one aspect, affinity tags for recombinant protein purification are described herein which, in some embodiments, can mitigate or overcome disadvantages of prior affinity tag systems. In some embodiments, for example, affinity tags described herein permit efficient elution of desired recombinant proteins with simplified solution systems, such as alkali metal salt solutions. An affinity tag described herein comprises an amino acid sequence including a repeating amino acid unit of BXXXBXX, wherein B is an amino acid selected from the group consisting of histidine, lysine and arginine and X is an amino acid selected from the group consisting of amino acids other than histidine, lysine and arginine.

Abstract: Compositions including pH sensitive lipid vesicles comprised of a lipid layer, an agent, and an organic halogen such that the agent is released from the vesicles after exposure to ionizing radiation. Methods of delivering the agent to a target in a subject using the compositions provided herein are also described. The methods allow for controlled release of the agent. The timing of release of the agent from the lipid vesicle may be controlled as well as the location of release by timing and localizing the exposure to ionizing radiation exposure.

Abstract: A control system for an axial skinning apparatus (100), including: •a force to cause a ceramic honeycomb part (110) to pass through the skinning apparatus (100); •a force that urges flowable cement on to the ceramic honeycomb part (110); •a sensor to detect the force on the cement; •a sensor to detect the force on the ceramic part; and •a controller (300) which receives: •a signal from the sensor on the flowable cement, •a signal from the sensor on the ceramic part (110), or both, and the controller (300) controls the pressure set point (310) of the cement source based on one or both of the received signals, and the controller (300) adjusts control parameters using feedback control and pseudo feed forward control. A method of using the axial skinning apparatus (100) is also disclosed.

Abstract: Compositions including pH sensitive lipid vesicles comprised of a lipid layer, an agent, and an organic halogen such that the agent is released from the vesicles after exposure to ionizing radiation. Methods of delivering the agent to a target in a subject using the compositions provided herein are also described. The methods allow for controlled release of the agent. The timing of release of the agent from the lipid vesicle may be controlled as well as the location of release by timing and localizing the exposure to ionizing radiation exposure.

Abstract: Compositions including pH sensitive lipid vesicles comprised of a lipid layer, an agent, and an organic halogen such that the agent is released from the vesicles after exposure to ionizing radiation. Methods of delivering the agent to a target in a subject using the compositions provided herein are also described. The methods allow for controlled release of the agent. The timing of release of the agent from the lipid vesicle may be controlled as well as the location of release by timing and localizing the exposure to ionizing radiation exposure.

Abstract: Disclosed is a ceramic honeycomb structure comprising a honeycomb body and a multilayered outer layer formed of a thick core layer applied and rapidly dried and a thin clad layer dried more gently to form a crack free dual skin layer. The core layer may have properties that are closer to those of the ceramic honeycomb body in service than the clad layer that may provide a tough outer shell to withstand handling and assembly.

Abstract: A process for operating an axial skinning apparatus for continuous manufacture of skinned ceramic honeycomb parts, including: determining the physical process parameters of the apparatus including: the rheology of the flowable skin cement; the geometry of the part to be skinned; and the geometry of the annulus gap of the skinning chamber; and calculating a plurality of dimensionless pressure gradient values (Lambda (?)) according to the formula (1): ? = ( ? ? ? P ) ? R 2 ? m ? ? L ? ( R V ) n ( 1 ) where ?P, P, R, V, L, and m and n are as defined herein; plotting a plurality of manifold pressures versus a plurality of part velocities; and selecting at least one operating window based on the skin quality of a plurality of preliminarily skinned parts.

Abstract: In one aspect, affinity tags for recombinant protein purification are described herein which, in some embodiments, can mitigate or overcome disadvantages of prior affinity tag systems. In some embodiments, for example, affinity tags described herein permit efficient elution of desired recombinant proteins with simplified solution systems, such as alkali metal salt solutions. An affinity tag described herein comprises an amino acid sequence including a repeating amino acid unit of BXXXBXX, wherein B is an amino acid selected from the group consisting of histidine, lysine and arginine and X is an amino acid selected from the group consisting of amino acids other than histidine, lysine and arginine.

Abstract: In one aspect, affinity tags for recombinant protein purification are described herein which, in some embodiments, can mitigate or overcome disadvantages of prior affinity tag systems. In some embodiments, for example, affinity tags described herein permit efficient elution of desired recombinant proteins with simplified solution systems, such as alkali metal salt solutions. An affinity tag described herein comprises an amino acid sequence including a repeating amino acid unit of BXXXBXX, wherein B is an amino acid selected from the group consisting of histidine, lysine and arginine and X is an amino acid selected from the group consisting of amino acids other than histidine, lysine and arginine.

Abstract: The present invention relates to excitation of hydrocarbons for catalytic type oxidation reactions, and more particularly, to treatment of excess methane emissions in a natural gas fueled engine to promote relatively more efficient catalytic methane oxidation reactions.

Abstract: In one aspect, affinity tags for recombinant protein purification are described herein which, in some embodiments, can mitigate or overcome disadvantages of prior affinity tag systems. In some embodiments, for example, affinity tags described herein permit efficient elution of desired recombinant proteins with simplified solution systems, such as alkali metal salt solutions. An affinity tag described herein comprises an amino acid sequence including a repeating amino acid unit of BXXXBXX, wherein B is an amino acid selected from the group consisting of histidine, lysine and arginine and X is an amino acid selected from the group consisting of amino acids other than histidine, lysine and arginine.

Abstract: A control system for an axial skinning apparatus (100), including: •a force to cause a ceramic honeycomb part (110) to pass through the skinning apparatus (100); •a force that urges flowable cement on to the ceramic honeycomb part (110); •a sensor to detect the force on the cement; •a sensor to detect the force on the ceramic part; and•a controller (300) which receives: •a signal from the sensor on the flowable cement, •a signal from the sensor on the ceramic part (110), or both, and the controller (300) controls the pressure set point (310) of the cement source based on one or both of the received signals, and the controller (300) adjusts control parameters using feedback control and pseudo feed forward control. A method of using the axial skinning apparatus (100) is also disclosed.

Abstract: Disclosed is a ceramic honeycomb structure comprising a honeycomb body and a multilayered outer layer formed of a thick core layer applied and rapidly dried and a thin clad layer dried more gently to form a crack free dual skin layer. The core layer may have properties that are closer to those of the ceramic honeycomb body in service than the clad layer that may provide a tough outer shell to withstand handling and assembly.

Abstract: Disclosed is a ceramic honeycomb structure comprising a honeycomb body and a multilayered outer layer formed of a thick core layer applied and rapidly dried and a thin clad layer dried more gently to form a crack free dual skin layer. The core layer may have properties that are closer to those of the ceramic honeycomb body in service than the clad layer that may provide a tough outer shell to withstand handling and assembly.

Abstract: The present invention encompasses compositions and methods for effectively treating at least one symptom or sign of methamphetamine use, or for slowing the rate of (+) methamphetamine entry into the brain of a subject. The method comprises administering an effective amount of an anti-(+) methamphetamine antibody to a subject.

Abstract: A process for operating an axial skinning apparatus for continuous manufacture of skinned ceramic honeycomb parts, including: determining the physical process parameters of the apparatus including: the rheology of the flowable skin cement; the geometry of the part to be skinned; and the geometry of the annulus gap of the skinning chamber; and calculating a plurality of dimensionless pressure gradient values (Lambda (?)) according to the formula (1): ? = ( ? ? ? P ) ? R 2 ? m ? ? L ? ( R V ) n ( 1 ) where ?P, P, R, V, L, and m and n are as defined herein; plotting a plurality of manifold pressures versus a plurality of part velocities; and selecting at least one operating window based on the skin quality of a plurality of preliminarily skinned parts.

Abstract: Compositions including pH sensitive lipid vesicles comprised of a lipid layer, an agent, and an organic halogen such that the agent is released from the vesicles after exposure to ionizing radiation. Methods of delivering the agent to a target in a subject using the compositions provided herein are also described. The methods allow for controlled release of the agent. The timing of release of the agent from the lipid vesicle may be controlled as well as the location of release by timing and localizing the exposure to ionizing radiation exposure.

Abstract: The present invention encompasses compositions and methods for effectively treating at least one symptom or sign of methamphetamine use, or for slowing the rate of (+) methamphetamine entry into the brain of a subject. The method comprises administering an effective amount of an anti-(+) methamphetamine antibody to a subject.

Abstract: Honeycomb ceramic wall flow filters exhibiting reduced plug depth variability, produced by introducing flowable ceramic plugging cements into the ends of selected channels in the honeycombs and wherein the ceramic plugging cements consist of shear-conditioned mixtures exhibiting reduced viscosity differentials.