Patents by Inventor Ralph Kelly
Ralph Kelly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10232016Abstract: The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.Type: GrantFiled: September 3, 2015Date of Patent: March 19, 2019Assignees: Acorda Therapeutics, Inc., Beth Israel Deaconess Medical Center, Inc., The Brigham and Women's Hospital, Inc.Inventors: Mark Marchionni, Ralph Kelly, Beverly Lorell, Douglas B. Sawyer
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Publication number: 20160113998Abstract: The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.Type: ApplicationFiled: September 3, 2015Publication date: April 28, 2016Inventors: Mark Marchionni, Ralph Kelly, Beverly Lorell, Douglas B. Sawyer
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Patent number: 9099008Abstract: A motion platform for use with a video simulation system is described. The platform is configured to provide simultaneous roll-axis and yaw-axis motion about a pivot point for simulating a aircraft environment. Additionally, the motion platform is configured to achieve motion using a single linear actuator, and thus is provided at a significantly reduced cost compared to conventional motion platforms. Other benefits of the motion platform include improved power efficiency, reduced weight for increased portability, and reduced maintenance due to only one linear actuator driving the system.Type: GrantFiled: December 16, 2013Date of Patent: August 4, 2015Assignee: FLYIT SIMULATORS, INC.Inventors: Terry J. Simpkins, Jr., Terry J. Simpkins, Sr., Ralph Kelly Simpkins
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Publication number: 20150170541Abstract: A motion platform for use with a video simulation system is described. The platform is configured to provide simultaneous roll-axis and yaw-axis motion about a pivot point for simulating a aircraft environment. Additionally, the motion platform is configured to achieve motion using a single linear actuator, and thus is provided at a significantly reduced cost compared to conventional motion platforms. Other benefits of the motion platform include improved power efficiency, reduced weight for increased portability, and reduced maintenance due to only one linear actuator driving the system.Type: ApplicationFiled: December 16, 2013Publication date: June 18, 2015Applicant: Flyit Simulators, Inc.Inventors: Terry J. Simpkins, JR., Terry J. Simpkins, SR., Ralph Kelly Simpkins
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Patent number: 8394761Abstract: The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.Type: GrantFiled: November 9, 2011Date of Patent: March 12, 2013Assignees: Beth Israel Deaconess Medical Center, The Brigham and Women's Hospital, Inc., Acorda Therapeutics, Inc.Inventors: Mark Marchionni, Ralph Kelly, Beverly Lorell, Douglas B. Sawyer
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Publication number: 20120065130Abstract: The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.Type: ApplicationFiled: November 9, 2011Publication date: March 15, 2012Inventors: Mark Marchionni, Ralph Kelly, Beverly Lorell, Douglas B. Sawyer
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Patent number: 8076283Abstract: The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.Type: GrantFiled: December 29, 2009Date of Patent: December 13, 2011Assignees: Acorda Therapeutics, Inc., Beth Israel Deaconesss Medical Center, The Brigham and Women's Hospital, Inc.Inventors: Mark Marchionni, Ralph Kelly, Beverly Lorell, Douglas B. Sawyer
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Publication number: 20100267618Abstract: The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.Type: ApplicationFiled: December 29, 2009Publication date: October 21, 2010Inventors: Mark Marchionni, Ralph Kelly, Beverly Lorell, Douglas B. Sawyer
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Patent number: 7662772Abstract: The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.Type: GrantFiled: August 22, 2003Date of Patent: February 16, 2010Assignees: Acorda Therapeutics, Inc., Beth Israel Deaconess Medical Center, The Brigham and Women's Hospital, Inc.Inventors: Mark Marchionni, Ralph Kelly, Beverly Lorell, Douglas B. Sawyer
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Publication number: 20070196379Abstract: The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.Type: ApplicationFiled: August 22, 2003Publication date: August 23, 2007Inventors: Mark Marchionni, Ralph Kelly, Beverly Lorell, Douglas Sawyer
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Publication number: 20070102996Abstract: A trailer brake system includes a full power hydraulic brake system that is electrically controlled by a system control unit. The trailer brake system includes a power unit that maintains a pressurized supply of hydraulic fluid and a brake control unit that is fluidly connected between the power unit and trailer wheel brake components. The power unit includes an electric motor driven pump and accumulator that is in fluid communication with a trailer supply reservoir. The brake control unit includes an inlet valve that is fluidly connected to the accumulator and an outlet valve that is fluidly connected to the trailer supply reservoir. The system control unit generates control signals to the power unit and brake control unit to respectively maintain a desired pressure level in the accumulator, and to apply the trailer wheel brake components through the brake control unit.Type: ApplicationFiled: November 10, 2005Publication date: May 10, 2007Inventors: Ralph Kelly, Dirk Wohltmann
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Patent number: 6635249Abstract: The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.Type: GrantFiled: April 23, 1999Date of Patent: October 21, 2003Assignee: CeNes Pharmaceuticals, Inc.Inventors: Mark Marchionni, Ralph Kelly, Beverly Lorell, Douglas B. Sawyer
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Patent number: 4160819Abstract: A method of inhibiting or reducing the irritation of skin resulting from allergic contact dermatitis, caused by contact with natural or synthetic allergenic agents, e.g. poison ivy, and dinitrochlorobenzene, respectively, is described. The method comprises applying to the skin an irritating reducing effective amount of a protective agent which is an organic compound having at least two polar groups, e.g. carboxyl groups, separated by a chain of at least 15 atoms the majority of which are carbon atoms and optionally containing a cyclic moiety of at least 5 atoms, prior to contact of the skin with the allergenic agent. The protective agent may be combined in a pharmacologically acceptable base for application to the skin.Type: GrantFiled: January 20, 1978Date of Patent: July 10, 1979Assignee: Cincinnati Milacron, Inc.Inventors: Sharon G. Willer, Paul R. Yust, Ralph Kelly
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Patent number: 4144319Abstract: A method of inhibiting or reducing the irritation of skin resulting from allergic contact dermatitis, caused by contact with natural or synthetic allergenic agents, e. g. poison ivy, and dinitrochlorobenzene, respectively, is described. The method comprises applying to the skin an irritating reducing effective amount of a protective agent which is an organic compound having at least two polar groups, e.g. carboxyl groups, separated by a chain of at least 15 atoms the majority of which are carbon atoms and optionally containing a cyclic moiety of at least 5 atoms, prior to contact of the skin with the allergenic agent. The protective agent may be combined in a pharmacologically acceptable base for application to the skin.Type: GrantFiled: January 20, 1978Date of Patent: March 13, 1979Assignee: Cincinnati Milacron, Inc.Inventors: Sharon G. Willer, Paul R. Yust, Ralph Kelly
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Patent number: 4141966Abstract: A method of inhibiting or reducing the irritation of skin resulting from allergic contact dermatitis, caused by contact with natural or synthetic allergenic agents, e.g. poison ivy, and dinitrochlorobenzene, respectively, is described. The method comprises applying to the skin an irritating reducing effective amount of a protective agent which is an organic compound having at least two polar groups, e.g. carboxyl groups, separated by a chain of at least 15 atoms the majority of which are carbon atoms and optionally containing a cyclic moiety of at least 5 atoms, prior to contact of the skin with the allergenic agent. The protective agent may be combined in a pharmacologically acceptable base for application to the skin.Type: GrantFiled: January 20, 1978Date of Patent: February 27, 1979Assignee: Cincinnati MilacronInventors: Sharon G. Willer, Paul R. Yust, Ralph Kelly
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Patent number: 4137301Abstract: A method of inhibiting or reducing the irritation of skin resulting from allergic contact dermatitis, caused by contact with natural or synthetic allergenic agents, e.g. poison ivy, and dinitrochlorobenzene, respectively, is described. The method comprises applying to the skin an irritating reducing effective amount of a protective agent which is an organic compound having at least two polar groups, e.g. carboxyl groups, separated by a chain of at least 15 atoms the majority of which are carbon atoms and optionally containing a cyclic moiety of at least 5 atoms, prior to contact of the skin with the allergenic agent. The protective agent may be combined in a pharmacologically acceptable base for application to the skin.Type: GrantFiled: January 20, 1978Date of Patent: January 30, 1979Assignee: Cincinnati Milacron, Inc.Inventors: Sharon G. Willer, Paul R. Yust, Ralph Kelly
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Patent number: 4076799Abstract: A method of inhibiting or reducing the irritation of skin resulting from allergic contact dermatitis, caused by contact with natural or synthetic allergenic agents, e.g. poison ivy, and dinitrochlorobenzene, respectively, is described. The method comprises applying to the skin an irritating reducing effective amount of a protective agent which is an organic compound having at least two polar groups, e.g. carboxyl groups, separated by a chain of at least 15 atoms the majority of which are carbon atoms and optionally containing a cyclic moiety of at least 5 atoms, prior to contact of the skin with the allergenic agent. The protective agent may be combined in a pharmacologically acceptable base for application to the skin.Type: GrantFiled: December 27, 1972Date of Patent: February 28, 1978Assignee: Cincinnati Milacron, Inc.Inventors: Sharon Gail Willer, Paul Ronald Yust, Ralph Kelly
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Patent number: 4075318Abstract: Compositions effective for protecting the skin from dermatologic irritation are formed by incorporating a protective agent which is an organic compound containing two or more polar groups, e.g. carboxyl groups, which are separated by at least 15 atoms the majority of which are carbon atoms and preferably containing a cyclic moiety of at least 5 atoms, e.g. the dimer of linoleic acid, in a pharmaceutically acceptable base.Type: GrantFiled: June 15, 1970Date of Patent: February 21, 1978Assignee: Cincinnati Milacron, Inc.Inventors: Ralph Kelly, Edmond Jean Ritter
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Patent number: 4067345Abstract: The hair is protected from damage by chemical agents, e.g. in bleaching, by either pretreatment with, or concurrent use of a protective agent and the damaging chemical. The protective agents disclosed are organic compounds containing two or more polar groups, e.g. carboxyl groups, which are separated by at least 15 atoms the majority of which are carbon atoms and preferably containing a cyclic moiety of at least 5 atoms, e.g. the dimer of linoleic acid.Type: GrantFiled: June 15, 1970Date of Patent: January 10, 1978Assignee: Cincinnati Milacron Inc.Inventors: Ralph Kelly, Edmond Jean Ritter
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Patent number: 4045550Abstract: Compositions effective for protecting the skin from dermatologic irritation are formed by incorporating a protective agent which is an organic compound containing two or more polar groups, e.g. carboxyl group, which are separated by at least 15 atoms the majority of which are carbon atoms and preferably containing a cyclic moiety of at least 5 atoms, e.g. the dimer of linoleic acid, in a pharmaceutically acceptable base.Type: GrantFiled: February 4, 1974Date of Patent: August 30, 1977Assignee: Cincinnati Milacron Inc.Inventors: Ralph Kelly, Edmond Jean Ritter