Patents by Inventor Ralph Kelly

Ralph Kelly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10232016
    Abstract: The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.
    Type: Grant
    Filed: September 3, 2015
    Date of Patent: March 19, 2019
    Assignees: Acorda Therapeutics, Inc., Beth Israel Deaconess Medical Center, Inc., The Brigham and Women's Hospital, Inc.
    Inventors: Mark Marchionni, Ralph Kelly, Beverly Lorell, Douglas B. Sawyer
  • Publication number: 20160113998
    Abstract: The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.
    Type: Application
    Filed: September 3, 2015
    Publication date: April 28, 2016
    Inventors: Mark Marchionni, Ralph Kelly, Beverly Lorell, Douglas B. Sawyer
  • Patent number: 9099008
    Abstract: A motion platform for use with a video simulation system is described. The platform is configured to provide simultaneous roll-axis and yaw-axis motion about a pivot point for simulating a aircraft environment. Additionally, the motion platform is configured to achieve motion using a single linear actuator, and thus is provided at a significantly reduced cost compared to conventional motion platforms. Other benefits of the motion platform include improved power efficiency, reduced weight for increased portability, and reduced maintenance due to only one linear actuator driving the system.
    Type: Grant
    Filed: December 16, 2013
    Date of Patent: August 4, 2015
    Assignee: FLYIT SIMULATORS, INC.
    Inventors: Terry J. Simpkins, Jr., Terry J. Simpkins, Sr., Ralph Kelly Simpkins
  • Publication number: 20150170541
    Abstract: A motion platform for use with a video simulation system is described. The platform is configured to provide simultaneous roll-axis and yaw-axis motion about a pivot point for simulating a aircraft environment. Additionally, the motion platform is configured to achieve motion using a single linear actuator, and thus is provided at a significantly reduced cost compared to conventional motion platforms. Other benefits of the motion platform include improved power efficiency, reduced weight for increased portability, and reduced maintenance due to only one linear actuator driving the system.
    Type: Application
    Filed: December 16, 2013
    Publication date: June 18, 2015
    Applicant: Flyit Simulators, Inc.
    Inventors: Terry J. Simpkins, JR., Terry J. Simpkins, SR., Ralph Kelly Simpkins
  • Patent number: 8394761
    Abstract: The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.
    Type: Grant
    Filed: November 9, 2011
    Date of Patent: March 12, 2013
    Assignees: Beth Israel Deaconess Medical Center, The Brigham and Women's Hospital, Inc., Acorda Therapeutics, Inc.
    Inventors: Mark Marchionni, Ralph Kelly, Beverly Lorell, Douglas B. Sawyer
  • Publication number: 20120065130
    Abstract: The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.
    Type: Application
    Filed: November 9, 2011
    Publication date: March 15, 2012
    Inventors: Mark Marchionni, Ralph Kelly, Beverly Lorell, Douglas B. Sawyer
  • Patent number: 8076283
    Abstract: The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.
    Type: Grant
    Filed: December 29, 2009
    Date of Patent: December 13, 2011
    Assignees: Acorda Therapeutics, Inc., Beth Israel Deaconesss Medical Center, The Brigham and Women's Hospital, Inc.
    Inventors: Mark Marchionni, Ralph Kelly, Beverly Lorell, Douglas B. Sawyer
  • Publication number: 20100267618
    Abstract: The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.
    Type: Application
    Filed: December 29, 2009
    Publication date: October 21, 2010
    Inventors: Mark Marchionni, Ralph Kelly, Beverly Lorell, Douglas B. Sawyer
  • Patent number: 7662772
    Abstract: The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.
    Type: Grant
    Filed: August 22, 2003
    Date of Patent: February 16, 2010
    Assignees: Acorda Therapeutics, Inc., Beth Israel Deaconess Medical Center, The Brigham and Women's Hospital, Inc.
    Inventors: Mark Marchionni, Ralph Kelly, Beverly Lorell, Douglas B. Sawyer
  • Publication number: 20070196379
    Abstract: The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.
    Type: Application
    Filed: August 22, 2003
    Publication date: August 23, 2007
    Inventors: Mark Marchionni, Ralph Kelly, Beverly Lorell, Douglas Sawyer
  • Publication number: 20070102996
    Abstract: A trailer brake system includes a full power hydraulic brake system that is electrically controlled by a system control unit. The trailer brake system includes a power unit that maintains a pressurized supply of hydraulic fluid and a brake control unit that is fluidly connected between the power unit and trailer wheel brake components. The power unit includes an electric motor driven pump and accumulator that is in fluid communication with a trailer supply reservoir. The brake control unit includes an inlet valve that is fluidly connected to the accumulator and an outlet valve that is fluidly connected to the trailer supply reservoir. The system control unit generates control signals to the power unit and brake control unit to respectively maintain a desired pressure level in the accumulator, and to apply the trailer wheel brake components through the brake control unit.
    Type: Application
    Filed: November 10, 2005
    Publication date: May 10, 2007
    Inventors: Ralph Kelly, Dirk Wohltmann
  • Patent number: 6635249
    Abstract: The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.
    Type: Grant
    Filed: April 23, 1999
    Date of Patent: October 21, 2003
    Assignee: CeNes Pharmaceuticals, Inc.
    Inventors: Mark Marchionni, Ralph Kelly, Beverly Lorell, Douglas B. Sawyer
  • Patent number: 4160819
    Abstract: A method of inhibiting or reducing the irritation of skin resulting from allergic contact dermatitis, caused by contact with natural or synthetic allergenic agents, e.g. poison ivy, and dinitrochlorobenzene, respectively, is described. The method comprises applying to the skin an irritating reducing effective amount of a protective agent which is an organic compound having at least two polar groups, e.g. carboxyl groups, separated by a chain of at least 15 atoms the majority of which are carbon atoms and optionally containing a cyclic moiety of at least 5 atoms, prior to contact of the skin with the allergenic agent. The protective agent may be combined in a pharmacologically acceptable base for application to the skin.
    Type: Grant
    Filed: January 20, 1978
    Date of Patent: July 10, 1979
    Assignee: Cincinnati Milacron, Inc.
    Inventors: Sharon G. Willer, Paul R. Yust, Ralph Kelly
  • Patent number: 4144319
    Abstract: A method of inhibiting or reducing the irritation of skin resulting from allergic contact dermatitis, caused by contact with natural or synthetic allergenic agents, e. g. poison ivy, and dinitrochlorobenzene, respectively, is described. The method comprises applying to the skin an irritating reducing effective amount of a protective agent which is an organic compound having at least two polar groups, e.g. carboxyl groups, separated by a chain of at least 15 atoms the majority of which are carbon atoms and optionally containing a cyclic moiety of at least 5 atoms, prior to contact of the skin with the allergenic agent. The protective agent may be combined in a pharmacologically acceptable base for application to the skin.
    Type: Grant
    Filed: January 20, 1978
    Date of Patent: March 13, 1979
    Assignee: Cincinnati Milacron, Inc.
    Inventors: Sharon G. Willer, Paul R. Yust, Ralph Kelly
  • Patent number: 4141966
    Abstract: A method of inhibiting or reducing the irritation of skin resulting from allergic contact dermatitis, caused by contact with natural or synthetic allergenic agents, e.g. poison ivy, and dinitrochlorobenzene, respectively, is described. The method comprises applying to the skin an irritating reducing effective amount of a protective agent which is an organic compound having at least two polar groups, e.g. carboxyl groups, separated by a chain of at least 15 atoms the majority of which are carbon atoms and optionally containing a cyclic moiety of at least 5 atoms, prior to contact of the skin with the allergenic agent. The protective agent may be combined in a pharmacologically acceptable base for application to the skin.
    Type: Grant
    Filed: January 20, 1978
    Date of Patent: February 27, 1979
    Assignee: Cincinnati Milacron
    Inventors: Sharon G. Willer, Paul R. Yust, Ralph Kelly
  • Patent number: 4137301
    Abstract: A method of inhibiting or reducing the irritation of skin resulting from allergic contact dermatitis, caused by contact with natural or synthetic allergenic agents, e.g. poison ivy, and dinitrochlorobenzene, respectively, is described. The method comprises applying to the skin an irritating reducing effective amount of a protective agent which is an organic compound having at least two polar groups, e.g. carboxyl groups, separated by a chain of at least 15 atoms the majority of which are carbon atoms and optionally containing a cyclic moiety of at least 5 atoms, prior to contact of the skin with the allergenic agent. The protective agent may be combined in a pharmacologically acceptable base for application to the skin.
    Type: Grant
    Filed: January 20, 1978
    Date of Patent: January 30, 1979
    Assignee: Cincinnati Milacron, Inc.
    Inventors: Sharon G. Willer, Paul R. Yust, Ralph Kelly
  • Patent number: 4076799
    Abstract: A method of inhibiting or reducing the irritation of skin resulting from allergic contact dermatitis, caused by contact with natural or synthetic allergenic agents, e.g. poison ivy, and dinitrochlorobenzene, respectively, is described. The method comprises applying to the skin an irritating reducing effective amount of a protective agent which is an organic compound having at least two polar groups, e.g. carboxyl groups, separated by a chain of at least 15 atoms the majority of which are carbon atoms and optionally containing a cyclic moiety of at least 5 atoms, prior to contact of the skin with the allergenic agent. The protective agent may be combined in a pharmacologically acceptable base for application to the skin.
    Type: Grant
    Filed: December 27, 1972
    Date of Patent: February 28, 1978
    Assignee: Cincinnati Milacron, Inc.
    Inventors: Sharon Gail Willer, Paul Ronald Yust, Ralph Kelly
  • Patent number: 4075318
    Abstract: Compositions effective for protecting the skin from dermatologic irritation are formed by incorporating a protective agent which is an organic compound containing two or more polar groups, e.g. carboxyl groups, which are separated by at least 15 atoms the majority of which are carbon atoms and preferably containing a cyclic moiety of at least 5 atoms, e.g. the dimer of linoleic acid, in a pharmaceutically acceptable base.
    Type: Grant
    Filed: June 15, 1970
    Date of Patent: February 21, 1978
    Assignee: Cincinnati Milacron, Inc.
    Inventors: Ralph Kelly, Edmond Jean Ritter
  • Patent number: 4067345
    Abstract: The hair is protected from damage by chemical agents, e.g. in bleaching, by either pretreatment with, or concurrent use of a protective agent and the damaging chemical. The protective agents disclosed are organic compounds containing two or more polar groups, e.g. carboxyl groups, which are separated by at least 15 atoms the majority of which are carbon atoms and preferably containing a cyclic moiety of at least 5 atoms, e.g. the dimer of linoleic acid.
    Type: Grant
    Filed: June 15, 1970
    Date of Patent: January 10, 1978
    Assignee: Cincinnati Milacron Inc.
    Inventors: Ralph Kelly, Edmond Jean Ritter
  • Patent number: 4045550
    Abstract: Compositions effective for protecting the skin from dermatologic irritation are formed by incorporating a protective agent which is an organic compound containing two or more polar groups, e.g. carboxyl group, which are separated by at least 15 atoms the majority of which are carbon atoms and preferably containing a cyclic moiety of at least 5 atoms, e.g. the dimer of linoleic acid, in a pharmaceutically acceptable base.
    Type: Grant
    Filed: February 4, 1974
    Date of Patent: August 30, 1977
    Assignee: Cincinnati Milacron Inc.
    Inventors: Ralph Kelly, Edmond Jean Ritter