Abstract: A device containing a retaining mechanism comprising: a resiliently biased latch member adapted for motion between at least three positions; a fusible retaining member having at least one engagement surface configured to engage with and act as a stop to the motion of the latch member between two of said positions; and a heating member positioned adjacent to the retaining member; wherein one motion of the latch member between said positions causes it to engage with the fusible retaining member and stop said motion, and activation of the heating member affects at least a portion of the fusible retaining member causing it to soften, melt, weaken or break allowing the latch member to move so as to release the latch member for a further motion between said positions

Abstract: A medical device comprising a multilayer printed circuit board (PCB) comprising a heating element on an inner layer of the PCB; a single cell electrical power source to power the heating element; and a chamber adapted to contain a liquid, at least part of said chamber being defined by a thermally conductive material configured to provide a thermal transfer interface between the chamber and the PCB.

Abstract: A device for use in the analysis of a biomolecule in a liquid sample, the device having at least three zones for accommodating at least part of the liquid sample, transfer means for transferring at least part of the liquid sample from a first zone to a second zone and for subsequently transferring at least part of the liquid sample from the second zone to a third zone along respective flow paths, a mechanically powered driver for operating the transfer means, a flow controller for selectively opening the flow paths between the zones, and a manually-operated common actuating member movable between a first and a second position to sequentially control both the mechanically powered driver and the flow controller to achieve transfer of at least part of the liquid sample between said zones, in which movement of the manually-operated common actuating member from the first position to the second position acts on the mechanically powered driver to achieve transfer of at least part of the liquid sample from the first

Abstract: A device for use in the analysis of a biomolecule in a liquid sample, the device having a plurality of zones for accommodating at least part of the liquid sample, transfer means for transferring at least part of the liquid sample from one to another of said zones along a respective flow path, mechanically powered drive means for operating the transfer means, flow control means for selectively opening one or more flow path between the zones, and a common actuating member which sequentially controls both the mechanically powered drive means and the flow control means to achieve transfer of at least part of the liquid sample between said zones.

Abstract: The invention provides in one aspect a drug delivery device comprising a drug container assembly containing a drug, and a plunger positioned within the container assembly, the drug container assembly having an outlet for dispensing the drug, wherein, in an initial position, the outlet is sealed; a drive mechanism comprising a first stored energy source operable to apply pressure on the plunger or the drug container to pressurise the drug, and a first release mechanism operable to unseal the outlet after the drug has been pressurised.

Abstract: The invention provides in one aspect a drug delivery device comprising a drug container assembly containing a drug, and a plunger positioned within the container assembly, the drug container assembly having an outlet for dispensing the drug, wherein, in an initial position, the outlet is sealed; a drive mechanism comprising a first stored energy source operable to apply pressure on the plunger or the drug container to pressurise the drug, and a first release mechanism operable to unseal the outlet after the drug has been pressurised.

Abstract: There is provided an electronically controlled, motor-driven, breath actuated metered dose inhaler for delivering aerosolized medicament or other matter to a user. The inhaler may comprise a base housing including a motor-driven actuator and other system components and a removable aerosol cartridge insertably receivable in the base housing. The inhaler may be paired with a smart phone or other client computing device to provide additional functionality, such as to provide instructional information and feedback regarding usage of the inhaler, to generate and display dosage tracking information, and to provide alerts and reminders to a user of the inhaler or others.

Abstract: There is provided an electronically controlled, motor-driven, breath actuated metered dose inhaler for delivering aerosolized medicament or other matter to a user. The inhaler may comprise a base housing including a motor-driven actuator and other system components and a removable aerosol cartridge insertably receivable in the base housing. The inhaler may be paired with a smart phone or other client computing device to provide additional functionality, such as to provide instructional information and feedback regarding usage of the inhaler, to generate and display dosage tracking information, and to provide alerts and reminders to a user of the inhaler or others.

Abstract: There is provided an electronically controlled, motor-driven, breath actuated metered dose inhaler for delivering aerosolized medicament or other matter to a user. The inhaler may comprise a base housing including a motor-driven actuator and other system components and a removable aerosol cartridge insertably receivable in the base housing. The inhaler may be paired with a smart phone or other client computing device to provide additional functionality, such as to provide instructional information and feedback regarding usage of the inhaler, to generate and display dosage tracking information, and to provide alerts and reminders to a user of the inhaler or others.

Abstract: A pre-filled drug delivery device, comprising a housing, a drug container within the housing and containing a drug; a plunger held within the drug container, movement of the plunger within the drug container being operative to dispense the drug from the drug container through an outlet; and a drive mechanism within the housing including a stored energy source and a plunger rod held in locked position against the stored energy source prior to activation of the device, wherein on activation of the device the stored energy source moves the plunger rod such that the plunger rod moves the plunger within the housing wherein the plunger rod comprises a longitudinal shaft formed from sheet metal, wherein the sheet metal defines a plane, and wherein the sheet metal is deformed so that the longitudinal shaft comprises an out-of-plane engagement surface, the out-of-plane engagement surface configured to engage a retaining surface on the housing or on a component of the drive mechanism, to hold the plunger rod in the loc

Abstract: The invention provides in one aspect a drug delivery device comprising a drug container assembly containing a drug, and a plunger positioned within the container assembly, the drug container assembly having an outlet for dispensing the drug, wherein, in an initial position, the outlet is sealed; a drive mechanism comprising a first stored energy source operable to apply pressure on the plunger or the drug container to pressurise the drug, and a first release mechanism operable to unseal the outlet after the drug has been pressurised.

Abstract: The invention provides in one aspect a drug delivery device comprising a drug container (16), and a plunger (18) positioned within the container assembly, the drug container assembly having an outlet for dispensing the drug, wherein, in an initial position, the outlet is sealed; a drive mechanism comprising a first stored energy source (42) operable to apply pressure on the plunger or the drug container to pressurize the drug, and a first release mechanism operable to unseal the outlet after the drug has been pressurized.

Abstract: The invention provides in one aspect a drug delivery device comprising a drug container (16), and a plunger (18) positioned within the container assembly, the drug container assembly having an outlet for dispensing the drug, wherein, in an initial position, the outlet is sealed; a drive mechanism comprising a first stored energy source (42) operable to apply pressure on the plunger or the drug container to pressurise the drug, and a first release mechanism operable to unseal the outlet after the drug has been pressurised.

Abstract: A pre-filled drug delivery device, comprising a housing, a drug container within the housing and containing a drug; a plunger held within the drug container, movement of the plunger within the drug container being operative to dispense the drug from the drug container through an outlet; and a drive mechanism within the housing including a stored energy source and a plunger rod held in locked position against the stored energy source prior to activation of the device, wherein on activation of the device the stored energy source moves the plunger rod such that the plunger rod moves the plunger within the housing wherein the plunger rod comprises a longitudinal shaft formed from sheet metal, wherein the sheet metal defines a plane, and wherein the sheet metal is deformed so that the longitudinal shaft comprises an out-of-plane engagement surface, the out-of-plane engagement surface configured to engage a retaining surface on the housing or on a component of the drive mechanism, to hold the plunger rod in the loc

Abstract: There is provided an injector device comprising a housing (26), a drug container (10) positioned in the housing; a drug delivery mechanism associated with the drug container, the drug delivery mechanism comprising a stored energy source; an activation member (18) coupled to the housing, the activation member configured to contact the injection site in use and movable relative to the housing to an activation position to activate the drug delivery mechanism; and a removable cap (134) coupled to the activation member and to the housing, wherein in a first position a first portion of the housing engages the activation member to prevent the activation member from moving into the activation position, and wherein a portion of the cap engages the housing to retain the first portion of the housing in the first position such that the activation member is prevented from moving into the activation position until the cap is uncoupled from the activation member.

Abstract: A hand-held dispenser (1) for dispensing a multiplicity of unit products (3) comprises a container (100) for containing the unit products which has an access opening (107) through which the unit products are able to be removed from the container and a dispensing module (300) which is adapted to be connected to the container in an operational position in which the dispensing module covers the access opening. The dispensing module has an internal volume (307), into which the unit products are transferable from the container through the access opening when the dispensing module is in the operational position, an outlet opening (311) which communicates with the internal volume, and a dispensing mechanism (350) which operates to dispense a predetermined number of unit products from the outlet opening on actuation thereof.

Abstract: A hand-held dispenser (1) for dispensing a multiplicity of unit products (3) having a storage area (100) for storing the unit products, an outlet opening (311) through which the unit products are dispensable from the dispenser, a dispensing mechanism (350) actuable to dispense the unit products through the outlet opening, and a timing mechanism (409,411,413) adapted in use to time the period since last dispensing of a unit product.

Abstract: A hand-held dispenser (1) for dispensing a multiplicity of unit products (3) having a storage area (100) for storing the unit products, an outlet opening (311) through which the unit products are dispensable from the dispenser and a dispensing mechanism (350) adapted to dispense a predetermined number of said unit products through the outlet opening per actuation thereof. The dispenser is adapted such that the dispensing mechanism is actuable by pushing the dispenser into a palm of a user and such that the associated predetermined number of unit products is dispensed into that palm.