Patents by Inventor Ralph Ma

Ralph Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230130619
    Abstract: Embodiments of the disclosure involve training machine learned models using DNA-encoded library experimental data outputs and for deploying the trained machine learned models for conducting a virtual compound screen, for performing a hit selection and analysis, or for predicting binding affinities between compounds and targets. Machine learned models are trained using one or more augmentations that selectively expand molecular representations of a training dataset. Furthermore, machine learned models are trained to account for confounding covariates, thereby improving the machine learned models' abilities to conduct a virtual screen, perform a hit selection, and to predict binding affinities.
    Type: Application
    Filed: October 21, 2022
    Publication date: April 27, 2023
    Inventors: Ralph Ma, Gabriel Dreiman, Fiorella Ruggiu, Adam Riesselman, Bowen Liu, Mohammad Muneeb Sultan