Patents by Inventor Ralph Meyer
Ralph Meyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240009582Abstract: A gyroscope includes a frame that surrounds a wheel and a weight that is connected to the wheel. A pair of wheel axles extend from the wheel and connect the wheel to the frame so that the wheel may rotate with respect to the frame. The frame also includes end pivot frames that provide a mounting point for end pivots to be removably attached to the frame. A zip cord may interact with a starting gear on one of the wheel axles to cause rotation of the wheel with respect to the frame.Type: ApplicationFiled: July 11, 2023Publication date: January 11, 2024Applicant: Tedco Inc.Inventors: Jonathan Patrick Meyer, Ralph Meyer
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Publication number: 20140186311Abstract: The invention relates to a method for transiently immortalizing cells according to which immortalization proteins are introduced into the cells from outside. The invention also relates to a method for producing cells according to which organ-related cells are transiently immortalized by the exogenous supply of immortalization proteins and are remortalized after their expansion. The invention further relates to the cells produced according to the inventive method, to the use of said cells for producing a transplant and to the immortalization proteins used in the method.Type: ApplicationFiled: January 21, 2014Publication date: July 3, 2014Applicant: HEART BIOSYSTEMS GMBHInventors: Jan-Heiner Kupper, Ralph Meyer, Mirella Meyer-Ficca, Anne Kuhn
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Patent number: 8568972Abstract: A DNA construct is described which contains a fusion gene under the control of a promoter. The fusion gene comprises at least one resistance gene and at least one reporter gene and is slightly toxic to a host cell transfected with that DNA construct. That DNA construct can be encoded on a plasmid or a virus. Further, a method is described for using the DNA construct to identify substances that may cause a differentiation in eukaryotic cells.Type: GrantFiled: July 6, 2009Date of Patent: October 29, 2013Assignee: Medicyte GmbHInventors: Jan-Heiner Kuepper, Reinhard Kandolf, Ralph Meyer
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Publication number: 20130035287Abstract: The invention relates to a method for transiently immortalizing cells according to which immortalization proteins are introduced into the cells from outside. The invention also relates to a method for producing cells according to which organ-related cells are transiently immortalized by the exogenous supply of immortalization proteins and are remortalized after their expansion. The invention further relates to the cells produced according to the inventive method, to the use of said cells for producing a transplant and to the immortalization proteins used in the method.Type: ApplicationFiled: June 22, 2012Publication date: February 7, 2013Applicant: HEART BIOSYSTEMS GMBHInventors: Jan-Heiner Kupper, Ralph Meyer, Mirella Meyer-Ficca, Anne Kuhn
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Publication number: 20090291429Abstract: A DNA construct is described which contains a fusion gene under the control of a promoter. The fusion gene comprises at least one resistance gene and at least one reporter gene and is slightly toxic to a host cell transfected with that DNA construct. That DNA construct can be encoded on a plasmid or a virus. Further, a method is described for using the DNA construct to identify substances that may cause a differentiation in eukaryotic cells.Type: ApplicationFiled: July 6, 2009Publication date: November 26, 2009Inventors: Jan-Heiner KUEPPER, Reinhard KANDOLF, Ralph MEYER
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Publication number: 20080221058Abstract: The invention relates to a vector for the gene therapeutic treatment of tumors, especially in connection with radiotherapy. Said vector is provided with a therapeutic gene in the DNA sequence thereof. The gene is controlled by the promoter for the catalytic subunit of the telomerase or by the promoter for cyclin A.Type: ApplicationFiled: February 13, 2008Publication date: September 11, 2008Inventors: Jan-Heinerr Kupper, Ralph Meyer, Mirella Meyer-Ficca, Reinhard Kandolf
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Patent number: 7351697Abstract: The invention relates to a vector for the gene therapeutic treatment of tumors, especially in connection with radiotherapy. Said vector is provided with a therapeutic gene in the DNA sequence thereof. The gene is controlled by the promoter for the catalytic subunit of the telomerase or by the promoter for cyclin A.Type: GrantFiled: July 21, 2005Date of Patent: April 1, 2008Inventors: Jan-Heinerr Küpper, Ralph Meyer, Mirella Meyer-Ficca, Reinhard Kandolf
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Publication number: 20070237754Abstract: The invention relates to a method for transiently immortalizing cells according to which immortalization proteins are introduced into the cells from outside. The invention also relates to a method for producing cells according to which organ-related cells are transiently immortalized by the exogenous supply of immortalization proteins and are remortalized after their expansion. The invention further relates to the cells produced according to the inventive method, to the use of said cells for producing a transplant and to the immortalization proteins used in the method.Type: ApplicationFiled: May 21, 2007Publication date: October 11, 2007Inventors: Jan-Heiner Kupper, Ralph Meyer, Mirella Meyer-Ficca, Anne Kuhn
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Publication number: 20070025971Abstract: A DNA construct is described which contains a fusion gene under the control of a promoter. The fusion gene comprises at least one resistance gene and at least one reporter gene and is slightly toxic to a host cell transfected with that DNA construct. That DNA construct can be encoded on a plasmid or a virus. Further, a method is described for using the DNA construct to identify substances that may cause a differentiation in eukaryotic cells.Type: ApplicationFiled: July 27, 2006Publication date: February 1, 2007Inventors: Jan-Heiner Kuepper, Reinhard Kandolf, Ralph Meyer
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Publication number: 20050281787Abstract: The invention relates to a vector for the gene therapeutic treatment of tumors, especially in connection with radiotherapy. Said vector is provided with a therapeutic gene in the DNA sequence thereof. The gene is controlled by the promoter for the catalytic subunit of the telomerase or by the promoter for cyclin A.Type: ApplicationFiled: July 21, 2005Publication date: December 22, 2005Inventors: Jan-Heinerr Kupper, Ralph Meyer, Mirella Meyer-Ficca, Reinhard Kandolf
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Publication number: 20050278025Abstract: A prosthesis for placement into a joint space between two or more bones is disclosed. The prosthesis includes a body formed from a pre-formed solid one piece elastomer, wherein the elastomer is formed from a synthetic organic polymer that is biocompatible and has a modulus of elasticity and a mechanical strength between 0.5 MPa and 75 MPa. The body having a shape contoured to fit within a joint space between the femoral condyle, tubercle, and tibial plateau without any means of attachment.Type: ApplicationFiled: June 10, 2004Publication date: December 15, 2005Inventors: David Ku, Ralph Meyer, Xavier Sarabia, Stephen Williams
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Publication number: 20050244969Abstract: The invention relates to a method for transiently immortalizing cells in which immortalizing proteins are introduced into the cells from the exterior, and to a method for obtaining cells in which organ-related cells are transiently immortalized by supplying immortalizing proteins externally and are remortalized after expansion. The invention furthermore relates to cells which are prepared by these methods, to the use of the cells for preparing a transplant and to immortalizing proteins which are to be used in the methods.Type: ApplicationFiled: October 7, 2002Publication date: November 3, 2005Inventors: Jan-Heiner Kupper, Ralph Meyer, Mirella Meyer-Ficca, Anne Kuhn
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Patent number: 6936595Abstract: The invention relates to a vector for the gene therapeutic treatment of tumours, especially in connection with radiotherapy. Said vector is provided with a therapeutic gene in the DNA sequence thereof. The gene is controlled by the promoter for the catalytic subunit of the telomerase or by the promoter for cyclin A.Type: GrantFiled: April 2, 2002Date of Patent: August 30, 2005Assignee: Heart BioSystems, GmbHInventors: Jan-Heiner Küpper, Ralph Meyer, Mirella Meyer-Ficca, Reinhard Kandolf
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Patent number: 6736793Abstract: A detachable balloon system includes an inflatable balloon with a self-sealing valve. The balloon has an elastomeric membrane and a proximal opening. The self-sealing valve is made up of a valve body for receiving an inflation instrument to inflate the balloon. The valve body is preferably formed of a biocompatible elastomeric material and includes a base portion and a sealing portion. The base portion is bonded to the elastomeric membrane so as to seal the proximal opening of the balloon. The sealing portion is located within the balloon and extends distally from the base into the balloon. The sealing portion is compressibly sealable in response to a pressure within the balloon following inflation of the balloon and removal of the inflation instrument. A balloon dispenser for housing a balloon prior to receipt of an inflation instrument is also described.Type: GrantFiled: November 5, 2001Date of Patent: May 18, 2004Assignee: AMS Research CorporationInventors: Ralph Meyer, John D. Walker, Paul Volpini, Michael J. Magliochetti
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Publication number: 20040014219Abstract: A DNA construct is described which contains a fusion gene under the control of a promoter. The fusion gene comprises at least one resistance gene and at least one reporter gene and is slightly toxic to a host cell transfected with that DNA construct. That DNA construct can be encoded on a plasmid or a virus. Further, a method is described for using the DNA construct to identify substances that may cause a differentiation in eukaryotic cells.Type: ApplicationFiled: May 8, 2003Publication date: January 22, 2004Inventors: Jan-Heiner Kuepper, Reinhard Kandolf, Ralph Meyer
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Publication number: 20030044385Abstract: The invention relates to a vector for the gene therapeutic treatment of tumours, especially in connection with radiotherapy. Said vector is provided with a therapeutic gene in the DNA sequence thereof. The gene is controlled by the promoter for the catalytic subunit of the telomerase or by the promoter for cyclin A.Type: ApplicationFiled: April 2, 2002Publication date: March 6, 2003Inventors: Jan-Heiner Kupper, Ralph Meyer, Mirella Meyer-Ficca, Reinhard Kandolf
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Publication number: 20020049465Abstract: A detachable balloon system includes an inflatable balloon with a self-sealing valve. The balloon has an elastomeric membrane and a proximal opening. The self-sealing valve is made up of a valve body for receiving an inflation instrument to inflate the balloon. The valve body is preferably formed of a biocompatible elastomeric material and includes a base portion and a sealing portion. The base portion is bonded to the elastomeric membrane so as to seal the proximal opening of the balloon. The sealing portion is located within the balloon and extends distally from the base into the balloon. The sealing portion is compressibly sealable in response to a pressure within the balloon following inflation of the balloon and removal of the inflation instrument. A balloon dispenser for housing a balloon prior to receipt of an inflation instrument is also described.Type: ApplicationFiled: November 5, 2001Publication date: April 25, 2002Inventors: Ralph Meyer, John D. Walker, Paul Volpini, Michael J. Magliochetti
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Patent number: 6312405Abstract: A detachable balloon system includes an inflatable balloon with a self-sealing valve. The balloon has an elastomeric membrane and a proximal opening. The self-sealing valve is made up of a valve body for receiving an inflation instrument to inflate the balloon. The valve body is preferably formed of a biocompatible elastomeric material and includes a base portion and a sealing portion. The base portion is bonded to the elastomeric membrane so as to seal the proximal opening of the balloon. The sealing portion is located within the balloon and extends distally from the base into the balloon. The sealing portion is compressibly sealable in response to a pressure within the balloon following inflation of the balloon and removal of the inflation instrument. A balloon dispenser for housing a balloon prior to receipt of an inflation instrument is also described.Type: GrantFiled: February 2, 1999Date of Patent: November 6, 2001Assignee: American Medical Systems, Inc.Inventors: Ralph Meyer, John D. Walker, Paul Volpini, Michael J. Magliochetti
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Patent number: 5101292Abstract: A connector link contains a distributor having demultiplexers and multiplexers for the division of a data signal having a high data rate or the division of up to n data signals having lower data rates onto n parallel data paths. As a result thereof, one data signal having a high data rate or a plurality of data signals having a lower data rate can be optionally transmitted. Generally, an auxiliary channel for the transmission of special information is also provided. A time-division multiplex signal that is redundantly coded is formed. A reception section contains corresponding, inverse devices for recovering the original data signals.Type: GrantFiled: July 5, 1990Date of Patent: March 31, 1992Assignee: Siemens AktiengesellschaftInventors: Hartmut Burghardt, Ralph Meyer