Patents by Inventor Ralph Mosley

Ralph Mosley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120202794
    Abstract: Disclosed herein are compounds useful for treating a viral infection, such as HCV.
    Type: Application
    Filed: January 19, 2012
    Publication date: August 9, 2012
    Applicant: PHARMASSET, INC.
    Inventors: MICHAEL JOSEPH SOFIA, RAMESH KAKARLA, JIAN LIU, DEVAN NADUTHAMBI, RALPH MOSLEY, HOLLY MICOLOCHICK STEUER
  • Publication number: 20060258840
    Abstract: The present invention features mutated forms of PPAR ligand binding domain polypeptides that: (1) bind a partial PPAR agonist; and (2) is bound or activated by a full PPAR agonist to a lesser extent than the wild-type receptor. The mutated ligand binding domain contains an amino acid sequence wherein one or more interactions that preferentially (preferably solely) occurs between a full PPAR agonist and the AF-2 domain of a wild-type PPAR are modified. Preferably, the mutated ligand binding domain is selectively bound or activated by a partial PPAR agonist.
    Type: Application
    Filed: January 16, 2004
    Publication date: November 16, 2006
    Inventors: Ralph Mosley, Brian McKeever, Joel Berger