Patents by Inventor Ralph Mueller

Ralph Mueller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12084099
    Abstract: A method for recognizing a rail vehicle wheel as well as an arrangement for recognizing a rail vehicle wheel. A specific detection pattern of the rail vehicle wheel to be identified is ascertained using rollover signal of a rail vehicle wheel to be identified, which is ascertained with the aid of a load measuring device arranged on a rail, the rollover signal describing a time characteristic of a rail load induced by the rail vehicle wheel to be identified on the rail equipped with the load measuring device during the rollover, and the specific detection pattern comprising one or multiple identification parameter(s)/characteristic value(s) ascertained using the rollover signal. The ascertained specific detection pattern of the rail vehicle wheel to be identified is compared with one or multiple predefined reference-specific detection pattern(s) of rail vehicle wheels, and the rail vehicle wheel to be identified is identified by the comparison.
    Type: Grant
    Filed: January 21, 2021
    Date of Patent: September 10, 2024
    Assignee: Schenck Process Europe GmbH
    Inventors: Ralph Mueller, Viktor Rais
  • Publication number: 20240238194
    Abstract: Orodispersible effervescent tablets comprising budesonide are administered to patients suffering from eosinophilic esophagitis whereby a complete mucosal healing (i.e., deep endoscopic AND deep histological remission) and even a deep disease remission (i.e., deep clinical AND deep endoscopic AND deep histological remission) is achieved by a treatment regimen of administering said orodispersible effervescent tablets for at least six weeks to twelve weeks for the induction period and thereafter up to three a years as maintenance treatment.
    Type: Application
    Filed: May 19, 2022
    Publication date: July 18, 2024
    Applicant: Dr. Falk Pharma GmbH
    Inventors: Rudolf WILHELM, Ralph MUELLER, Roland GREINWALD, Markus PROELS
  • Patent number: 11382860
    Abstract: Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.
    Type: Grant
    Filed: May 15, 2020
    Date of Patent: July 12, 2022
    Assignee: Dr. Falk Pharma GmbH
    Inventors: Roland Greinwald, Ralph Mueller, Markus Proels, Rudolf Wilhelm
  • Publication number: 20210139060
    Abstract: A method for recognizing a rail vehicle wheel as well as an arrangement for recognizing a rail vehicle wheel. A specific detection pattern of the rail vehicle wheel to be identified is ascertained using rollover signal of a rail vehicle wheel to be identified, which is ascertained with the aid of a load measuring device arranged on a rail, the rollover signal describing a time characteristic of a rail load induced by the rail vehicle wheel to be identified on the rail equipped with the load measuring device during the rollover, and the specific detection pattern comprising one or multiple identification parameter(s)/characteristic value(s) ascertained using the rollover signal. The ascertained specific detection pattern of the rail vehicle wheel to be identified is compared with one or multiple predefined reference-specific detection pattern(s) of rail vehicle wheels, and the rail vehicle wheel to be identified is identified by the comparison.
    Type: Application
    Filed: January 21, 2021
    Publication date: May 13, 2021
    Applicant: Schenck Process Europe GmbH
    Inventors: Ralph MUELLER, Viktor RAIS
  • Publication number: 20200337997
    Abstract: Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.
    Type: Application
    Filed: May 15, 2020
    Publication date: October 29, 2020
    Applicant: Dr. Falk Pharma GmbH
    Inventors: Roland GREINWALD, Ralph Mueller, Markus Proels, Rudolf Wilhelm
  • Patent number: 10695291
    Abstract: Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: June 30, 2020
    Assignee: Dr. Falk Pharma GmbH
    Inventors: Roland Greinwald, Ralph Mueller, Markus Proels, Rudolf Wilhelm
  • Publication number: 20190358155
    Abstract: Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.
    Type: Application
    Filed: June 17, 2019
    Publication date: November 28, 2019
    Applicant: Dr. Falk Pharma GmbH
    Inventors: Roland GREINWALD, Ralph MUELLER, Markus PROELS, Rudolf WILHELM
  • Patent number: 10369100
    Abstract: Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: August 6, 2019
    Assignee: Dr. Falk Pharma GmbH
    Inventors: Roland Greinwald, Ralph Mueller, Markus Proels, Rudolf Wilhelm
  • Publication number: 20180185277
    Abstract: Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.
    Type: Application
    Filed: December 6, 2017
    Publication date: July 5, 2018
    Applicant: Dr. Falk Pharma GmbH
    Inventors: Roland Greinwald, Ralph Mueller, Markus Proels, Rudolf Wilhelm
  • Patent number: 9867780
    Abstract: Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: January 16, 2018
    Assignee: Dr. Falk Pharma GmbH
    Inventors: Roland Greinwald, Ralph Mueller, Markus Proels, Rudolf Wilhelm
  • Publication number: 20160324772
    Abstract: Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.
    Type: Application
    Filed: December 18, 2014
    Publication date: November 10, 2016
    Applicant: DR. FALK PHARMA GMBH
    Inventors: Roland GREINWALD, Ralph MUELLER, Markus PROELS, Rudolf WILHELM
  • Patent number: 9234786
    Abstract: The object to create a system and a method which allows better running gear diagnosis of rail vehicles is achieved by the present invention by arranging a number of force measurement devices on the rail measurement zone to detect the forces and/or torques acting on the rail measurement zone, such that the system also comprises a number of sonic measurement devices for detecting the sound waves which occur when the rail vehicle travels over the rail measurement zone. The present invention thus offers a diagnostic system for analysis of the condition of wheel bearings and wheel geometries in particular in which the forces and sound waves occurring when the rail vehicle travels over the rail can be detected and analyzed, so that more reliable inferences about the condition of the running gear of the rail vehicle can be drawn from them.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: January 12, 2016
    Assignee: Schenck Process GmbH
    Inventors: Peter Groll, Ralph Mueller
  • Patent number: 8827174
    Abstract: A sleeper for supporting rails within a section of track for rail vehicles is provided, wherein the sleeper has elongated reinforcing elements extending along a longitudinal axis of the sleeper and is produced as a solid material sleeper having a cavity which extends between the reinforcing elements and from at least one outer face of the sleeper into the interior of the sleeper, and wherein the sleeper is designed for use with at least two different measurement value pick-up systems, wherein one of the measurement value pick-up systems is a temperature measurement value pick-up system having an infrared sensor which is accommodated by insertion into the cavity.
    Type: Grant
    Filed: August 22, 2012
    Date of Patent: September 9, 2014
    Assignee: Schenck Process GmbH
    Inventors: Peter Groll, Ralph Mueller, Martin Stillger
  • Patent number: 8359934
    Abstract: The object to configure a system for measuring loads during the wheel/rail contact of rail vehicles in such a manner that the occurring forces and/or torques can be measured in a reliable and realistic manner is solved by the present invention. Between the rail foot and the measuring device, at least one elastic element is arranged which has an elasticity which simulates the elasticity of a ballast bed. By means of the measuring system according to the invention, on the one hand, realistic conditions of a track system can be simulated and, on the other, a high metrological reproducibility of a load situation can be achieved.
    Type: Grant
    Filed: April 1, 2009
    Date of Patent: January 29, 2013
    Assignee: Schenck Process GmbH
    Inventors: Fritz Ehmke, Peter Groll, Ralph Mueller
  • Publication number: 20120325921
    Abstract: A sleeper for supporting rails within a section of track for rail vehicles is provided, wherein the sleeper has elongated reinforcing elements extending along a longitudinal axis of the sleeper and is produced as a solid material sleeper having a cavity which extends between the reinforcing elements and from at least one outer face of the sleeper into the interior of the sleeper, and wherein the sleeper is designed for use with at least two different measurement value pick-up systems, wherein one of the measurement value pick-up systems is a temperature measurement value pick-up system having an infrared sensor which is accommodated by insertion into the cavity.
    Type: Application
    Filed: August 22, 2012
    Publication date: December 27, 2012
    Inventors: Peter GROLL, Ralph Mueller, Martin Stillger
  • Publication number: 20110224863
    Abstract: The object to create a system and a method which allows better running gear diagnosis of rail vehicles is achieved by the present invention by arranging a number of force measurement devices on the rail measurement zone to detect the forces and/or torques acting on the rail measurement zone, such that the system also comprises a number of sonic measurement devices for detecting the sound waves which occur when the rail vehicle travels over the rail measurement zone. The present invention thus offers a diagnostic system for analysis of the condition of wheel bearings and wheel geometries in particular in which the forces and sound waves occurring when the rail vehicle travels over the rail can be detected and analyzed, so that more reliable inferences about the condition of the running gear of the rail vehicle can be drawn from them.
    Type: Application
    Filed: November 17, 2009
    Publication date: September 15, 2011
    Applicant: SCHENCK PROCESS GMBH
    Inventors: Peter Groll, Ralph Mueller
  • Publication number: 20110088487
    Abstract: The object to configure a system for measuring loads during the wheel/rail contact of rail vehicles in such a manner that the occurring forces and/or torques can be measured in a reliable and realistic manner is solved by the present invention. Between the rail foot and the measuring device, at least one elastic element is arranged which has an elasticity which simulates the elasticity of a ballast bed. By means of the measuring system according to the invention, on the one hand, realistic conditions of a track system can be simulated and, on the other, a high metrological reproducibility of a load situation can be achieved.
    Type: Application
    Filed: April 1, 2009
    Publication date: April 21, 2011
    Applicant: SCHENCK PROCESS GMBH
    Inventors: Fritz Ehmke, Peter Groll, Ralph Mueller
  • Patent number: 4146071
    Abstract: The present power driver handles fasteners of varying length mounted on a strip or belt, through a touch-down foot which accommodates fasteners of different length to eliminate wasted motion of the driver. The fasteners are also prevented by said touch-down foot from tipping or going into a workpiece at an angle. The depth to which the fasteners are driven into the workpiece is controllable and any irregularities in the mounting of the fasteners on the strip or belt are compensated.
    Type: Grant
    Filed: September 12, 1977
    Date of Patent: March 27, 1979
    Assignee: Firma Karl M. Reich Maschinenfabrik GmbH
    Inventors: Ralph Mueller, Heinz Schwarz