Patents by Inventor Ralph Mueller
Ralph Mueller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12084099Abstract: A method for recognizing a rail vehicle wheel as well as an arrangement for recognizing a rail vehicle wheel. A specific detection pattern of the rail vehicle wheel to be identified is ascertained using rollover signal of a rail vehicle wheel to be identified, which is ascertained with the aid of a load measuring device arranged on a rail, the rollover signal describing a time characteristic of a rail load induced by the rail vehicle wheel to be identified on the rail equipped with the load measuring device during the rollover, and the specific detection pattern comprising one or multiple identification parameter(s)/characteristic value(s) ascertained using the rollover signal. The ascertained specific detection pattern of the rail vehicle wheel to be identified is compared with one or multiple predefined reference-specific detection pattern(s) of rail vehicle wheels, and the rail vehicle wheel to be identified is identified by the comparison.Type: GrantFiled: January 21, 2021Date of Patent: September 10, 2024Assignee: Schenck Process Europe GmbHInventors: Ralph Mueller, Viktor Rais
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Publication number: 20240238194Abstract: Orodispersible effervescent tablets comprising budesonide are administered to patients suffering from eosinophilic esophagitis whereby a complete mucosal healing (i.e., deep endoscopic AND deep histological remission) and even a deep disease remission (i.e., deep clinical AND deep endoscopic AND deep histological remission) is achieved by a treatment regimen of administering said orodispersible effervescent tablets for at least six weeks to twelve weeks for the induction period and thereafter up to three a years as maintenance treatment.Type: ApplicationFiled: May 19, 2022Publication date: July 18, 2024Applicant: Dr. Falk Pharma GmbHInventors: Rudolf WILHELM, Ralph MUELLER, Roland GREINWALD, Markus PROELS
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Patent number: 11382860Abstract: Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.Type: GrantFiled: May 15, 2020Date of Patent: July 12, 2022Assignee: Dr. Falk Pharma GmbHInventors: Roland Greinwald, Ralph Mueller, Markus Proels, Rudolf Wilhelm
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Publication number: 20210139060Abstract: A method for recognizing a rail vehicle wheel as well as an arrangement for recognizing a rail vehicle wheel. A specific detection pattern of the rail vehicle wheel to be identified is ascertained using rollover signal of a rail vehicle wheel to be identified, which is ascertained with the aid of a load measuring device arranged on a rail, the rollover signal describing a time characteristic of a rail load induced by the rail vehicle wheel to be identified on the rail equipped with the load measuring device during the rollover, and the specific detection pattern comprising one or multiple identification parameter(s)/characteristic value(s) ascertained using the rollover signal. The ascertained specific detection pattern of the rail vehicle wheel to be identified is compared with one or multiple predefined reference-specific detection pattern(s) of rail vehicle wheels, and the rail vehicle wheel to be identified is identified by the comparison.Type: ApplicationFiled: January 21, 2021Publication date: May 13, 2021Applicant: Schenck Process Europe GmbHInventors: Ralph MUELLER, Viktor RAIS
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Publication number: 20200337997Abstract: Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.Type: ApplicationFiled: May 15, 2020Publication date: October 29, 2020Applicant: Dr. Falk Pharma GmbHInventors: Roland GREINWALD, Ralph Mueller, Markus Proels, Rudolf Wilhelm
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Patent number: 10695291Abstract: Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.Type: GrantFiled: June 17, 2019Date of Patent: June 30, 2020Assignee: Dr. Falk Pharma GmbHInventors: Roland Greinwald, Ralph Mueller, Markus Proels, Rudolf Wilhelm
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Publication number: 20190358155Abstract: Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.Type: ApplicationFiled: June 17, 2019Publication date: November 28, 2019Applicant: Dr. Falk Pharma GmbHInventors: Roland GREINWALD, Ralph MUELLER, Markus PROELS, Rudolf WILHELM
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Patent number: 10369100Abstract: Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.Type: GrantFiled: December 6, 2017Date of Patent: August 6, 2019Assignee: Dr. Falk Pharma GmbHInventors: Roland Greinwald, Ralph Mueller, Markus Proels, Rudolf Wilhelm
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Publication number: 20180185277Abstract: Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.Type: ApplicationFiled: December 6, 2017Publication date: July 5, 2018Applicant: Dr. Falk Pharma GmbHInventors: Roland Greinwald, Ralph Mueller, Markus Proels, Rudolf Wilhelm
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Patent number: 9867780Abstract: Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.Type: GrantFiled: December 18, 2014Date of Patent: January 16, 2018Assignee: Dr. Falk Pharma GmbHInventors: Roland Greinwald, Ralph Mueller, Markus Proels, Rudolf Wilhelm
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Publication number: 20160324772Abstract: Disclosed is an optimized pharmaceutical formulation for the treatment of inflammatory conditions of the esophagus. A pharmaceutical formulation in the form of an orodispersible effervescent tablet is stable, easy to produce, and can be used without dissolving same in a liquid. It is not necessary to drink anything with the tablet as this would reduce the time that the budesonide solution remains in the affected regions of the esophagus. The effervescent tablet of the invention surprisingly resulted in an unexpectedly high rate of histological remission in patients with active eosinophilic esophagitis.Type: ApplicationFiled: December 18, 2014Publication date: November 10, 2016Applicant: DR. FALK PHARMA GMBHInventors: Roland GREINWALD, Ralph MUELLER, Markus PROELS, Rudolf WILHELM
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Patent number: 9234786Abstract: The object to create a system and a method which allows better running gear diagnosis of rail vehicles is achieved by the present invention by arranging a number of force measurement devices on the rail measurement zone to detect the forces and/or torques acting on the rail measurement zone, such that the system also comprises a number of sonic measurement devices for detecting the sound waves which occur when the rail vehicle travels over the rail measurement zone. The present invention thus offers a diagnostic system for analysis of the condition of wheel bearings and wheel geometries in particular in which the forces and sound waves occurring when the rail vehicle travels over the rail can be detected and analyzed, so that more reliable inferences about the condition of the running gear of the rail vehicle can be drawn from them.Type: GrantFiled: November 17, 2009Date of Patent: January 12, 2016Assignee: Schenck Process GmbHInventors: Peter Groll, Ralph Mueller
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Patent number: 8827174Abstract: A sleeper for supporting rails within a section of track for rail vehicles is provided, wherein the sleeper has elongated reinforcing elements extending along a longitudinal axis of the sleeper and is produced as a solid material sleeper having a cavity which extends between the reinforcing elements and from at least one outer face of the sleeper into the interior of the sleeper, and wherein the sleeper is designed for use with at least two different measurement value pick-up systems, wherein one of the measurement value pick-up systems is a temperature measurement value pick-up system having an infrared sensor which is accommodated by insertion into the cavity.Type: GrantFiled: August 22, 2012Date of Patent: September 9, 2014Assignee: Schenck Process GmbHInventors: Peter Groll, Ralph Mueller, Martin Stillger
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Patent number: 8359934Abstract: The object to configure a system for measuring loads during the wheel/rail contact of rail vehicles in such a manner that the occurring forces and/or torques can be measured in a reliable and realistic manner is solved by the present invention. Between the rail foot and the measuring device, at least one elastic element is arranged which has an elasticity which simulates the elasticity of a ballast bed. By means of the measuring system according to the invention, on the one hand, realistic conditions of a track system can be simulated and, on the other, a high metrological reproducibility of a load situation can be achieved.Type: GrantFiled: April 1, 2009Date of Patent: January 29, 2013Assignee: Schenck Process GmbHInventors: Fritz Ehmke, Peter Groll, Ralph Mueller
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Publication number: 20120325921Abstract: A sleeper for supporting rails within a section of track for rail vehicles is provided, wherein the sleeper has elongated reinforcing elements extending along a longitudinal axis of the sleeper and is produced as a solid material sleeper having a cavity which extends between the reinforcing elements and from at least one outer face of the sleeper into the interior of the sleeper, and wherein the sleeper is designed for use with at least two different measurement value pick-up systems, wherein one of the measurement value pick-up systems is a temperature measurement value pick-up system having an infrared sensor which is accommodated by insertion into the cavity.Type: ApplicationFiled: August 22, 2012Publication date: December 27, 2012Inventors: Peter GROLL, Ralph Mueller, Martin Stillger
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Publication number: 20110224863Abstract: The object to create a system and a method which allows better running gear diagnosis of rail vehicles is achieved by the present invention by arranging a number of force measurement devices on the rail measurement zone to detect the forces and/or torques acting on the rail measurement zone, such that the system also comprises a number of sonic measurement devices for detecting the sound waves which occur when the rail vehicle travels over the rail measurement zone. The present invention thus offers a diagnostic system for analysis of the condition of wheel bearings and wheel geometries in particular in which the forces and sound waves occurring when the rail vehicle travels over the rail can be detected and analyzed, so that more reliable inferences about the condition of the running gear of the rail vehicle can be drawn from them.Type: ApplicationFiled: November 17, 2009Publication date: September 15, 2011Applicant: SCHENCK PROCESS GMBHInventors: Peter Groll, Ralph Mueller
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Publication number: 20110088487Abstract: The object to configure a system for measuring loads during the wheel/rail contact of rail vehicles in such a manner that the occurring forces and/or torques can be measured in a reliable and realistic manner is solved by the present invention. Between the rail foot and the measuring device, at least one elastic element is arranged which has an elasticity which simulates the elasticity of a ballast bed. By means of the measuring system according to the invention, on the one hand, realistic conditions of a track system can be simulated and, on the other, a high metrological reproducibility of a load situation can be achieved.Type: ApplicationFiled: April 1, 2009Publication date: April 21, 2011Applicant: SCHENCK PROCESS GMBHInventors: Fritz Ehmke, Peter Groll, Ralph Mueller
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Patent number: 4146071Abstract: The present power driver handles fasteners of varying length mounted on a strip or belt, through a touch-down foot which accommodates fasteners of different length to eliminate wasted motion of the driver. The fasteners are also prevented by said touch-down foot from tipping or going into a workpiece at an angle. The depth to which the fasteners are driven into the workpiece is controllable and any irregularities in the mounting of the fasteners on the strip or belt are compensated.Type: GrantFiled: September 12, 1977Date of Patent: March 27, 1979Assignee: Firma Karl M. Reich Maschinenfabrik GmbHInventors: Ralph Mueller, Heinz Schwarz