Abstract: The present invention relates to an active ingredient and a drug or composition, respectively, for use in reducing pathogenic germs in the human intestine or for use in reducing colonization of the human intestine with pathogenic germs, preferentially for the purpose of preventing, reducing or curing inflammatory diseases or preferentially for the purpose of prophylactic or therapeutic treatment of inflammatory diseases of the human body.

Abstract: The invention relates to a nucleic acid molecule, comprising a nucleic acid which codes for a polypeptide with chorismate mutase activity and derivatives thereof, whereby the derivatives have at least 10% of the chorismate mutase activity of the chorismate mutase, according to the identification number of the SEQ ID NO:2. The invention further relates to vectors containing nucleic acid molecules, to host cells comprising nucleic acid molecules and their use in methods for producing polypetides with chorismate mutase activity. The invention also relates to the polypeptides with chorismate mutase activity and antibodies which specifically recognize the same. In addition, the invention relates to methods for producing auxotrophic yeast strains using the nucleic acid molecules and to the preparation of the yeast strains.

Abstract: The invention relates to a nucleic acid molecule, comprising a nucleic acid which codes for a polypeptide with chorismate mutase activity and derivatives thereof, whereby the derivatives have at least 10% of the chorismate mutase activity of the chorismate mutase, according to the identification number of the SEQ ID NO:2. The invention further relates to vectors containing nucleic acid molecules, to host cells comprising nucleic acid molecules and their use in methods for producing polypetides with chorismate mutase activity. The invention also relates to the polypeptides with chorismate mutase activity and antibodies which specifically recognize the same. In addition, the invention relates to methods for producing auxotrophic yeast strains using the nucleic acid molecules and to the preparation of the yeast strains.

Abstract: Disclosed is an operational-temperature-stabilized wavelength-stabilized laser diode having an integrated temperature control unit. Such diode arrangement has combinations of the following features: at least one laser chip; heating provided by at least one PTC resistor such that a device operational temperature is controlled by this PTC resistor; a detector for determining the radiation emerging from the rear of the laser chip; an NTC resistor or a thermo-element for measuring the chip temperature. The laser chip serves a dual function of acting as a laser source and as a radiation detector, thereby eliminating any need for a separately provided radiation detector and resulting in a compact device. All the components required for temperature control, respectively, temperature stabilization, are miniaturized and integrated with the laser chip within a housing. The extremely small size of the invented laser diode opens a wide range of possible applications.