Patents by Inventor Ralph Schiess

Ralph Schiess has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240337659
    Abstract: A method for collecting information about the health status of a subject involving the quantitative detection, in serum, plasma or blood of the subject, of the concentration of at least four of the systems selected from the group consisting of: THBS1, LUM, FN1, LG3BP, MMP9, as well as PSA.
    Type: Application
    Filed: June 16, 2022
    Publication date: October 10, 2024
    Applicant: ProteoMedix AG
    Inventors: Ralph SCHIESS, Alcibiade ATHANASIOU, Ramy HUBER, Anja WITTIG
  • Publication number: 20240288433
    Abstract: Method for collecting information about the health status of a subject involving the quantitative detection, in serum, plasma or blood of the subject, of the concentration of THBS1, as well as the proportion of free PSA (% fPSA) in combination with data obtained from multi-parametric prostate magnetic resonance imaging data.
    Type: Application
    Filed: June 16, 2022
    Publication date: August 29, 2024
    Applicant: ProteoMedix AG
    Inventors: Ralph SCHIESS, Christian BRÜHLMANN, Oliver STRAUB, Alcibiade ATHANASIOU
  • Patent number: 11320435
    Abstract: A method for collecting information about the health status of a subject is proposed involving the quantitative detection, in serum, plasma or blood of the subject, of the concentration of THBS1, the proportion of free PSA (% fPSA), preferably including the concentration of at least one protein selected from the group consisting of CTSD, OLFM4, ICAM1.
    Type: Grant
    Filed: July 11, 2017
    Date of Patent: May 3, 2022
    Assignee: ProteoMedix AG
    Inventors: Ralph Schiess, Kathrin Endt, Alcibiade Athanasiou, Annalisa Macagno, Thomas Steuber
  • Publication number: 20190250163
    Abstract: A method for collecting information about the health status of a subject is proposed involving the quantitative detection, in serum, plasma or blood of the subject, of the concentration of THBS1, the proportion of free PSA (% fPSA), preferably including the concentration of at least one protein selected from the group consisting of CTSD, OLFM4, ICAM1.
    Type: Application
    Filed: July 11, 2017
    Publication date: August 15, 2019
    Applicant: ProteoMedix AG
    Inventors: Ralph SCHIESS, Kathrin ENDT, Alcibiade ATHANASIOU, Annalisa MACAGNO, Thomas STEUBER
  • Patent number: 10151755
    Abstract: The invention relates to biomarker assays based on protein/peptide biomarkers which show a pronounced differential behaviour between healthy and cancerous sample proteomes e.g. by mass spectrometric measurement and/or antibody-based assays such as an Enzyme-Linked Immunosorbent Assay (ELISA) determination of the protein biomarkers in serum, plasma or blood itself.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: December 11, 2018
    Assignees: ETH ZURICH, Kantonsspital St. Gallen
    Inventors: Wilhelm Krek, Igor Cima, Rudolf Aebersold, Ralph Schiess, Thomas Cerny, Silke Gillessen
  • Publication number: 20160274117
    Abstract: The invention relates to biomarker assays based on protein/peptide biomarkers which show a pronounced differential behaviour between healthy and cancerous sample proteomes e.g. by mass spectrometric measurement and/or antibody-based assays such as an Enzyme-Linked Immunosorbent Assay (ELISA) determination of the protein biomarkers in serum, plasma or blood itself.
    Type: Application
    Filed: June 1, 2016
    Publication date: September 22, 2016
    Applicants: ETH ZURICH, Kantonsspital St. Gallen
    Inventors: Wilhelm KREK, Igor CIMA, Rudolf AEBERSOLD, Ralph SCHIESS, Thomas CERNY, Silke GILLESSEN
  • Patent number: 9377463
    Abstract: The invention relates to a method for the determination of a cancer diagnostic/therapeutic biomarker assay and drug-targets including the following steps: (a) identification of potential candidate protein/peptide biomarkers and drug-targets based on the measurement of protein/peptide constituent concentrations in tissue sample proteomes as well as serum, plasma or any other derivatives of blood, or blood itself sample proteomes derived from healthy non-human mammalian individuals as well as from cancerous non-human mammalian individuals and qualitatively selecting as potential candidate protein/peptide biomarkers those which show a pronounced differential behavior between healthy and cancerous sample proteomes; (b) optional verification of the potential candidate protein/peptide biomarkers as identified in step (a) by quantitative mass spectrometric measurement of the potential candidate protein biomarkers in serum, plasma or any other derivatives of blood, or blood itself sample proteomes derived from health
    Type: Grant
    Filed: June 23, 2014
    Date of Patent: June 28, 2016
    Assignees: ETH ZURICH, Kantonsspital St. Gallen
    Inventors: Wilhelm Krek, Igor Cima, Rudolf Aebersold, Ralph Schiess, Thomas Cerny, Silke Gillessen
  • Publication number: 20140322732
    Abstract: The invention relates to a method for the determination of a cancer diagnostic/therapeutic biomarker assay and drug-targets including the following steps: (a) identification of potential candidate protein/peptide biomarkers and drug-targets based on the measurement of protein/peptide constituent concentrations in tissue sample proteomes as well as serum, plasma or any other derivatives of blood, or blood itself sample proteomes derived from healthy non-human mammalian individuals as well as from cancerous non-human mammalian individuals and qualitatively selecting as potential candidate protein/peptide biomarkers those which show a pronounced differential behaviour between healthy and cancerous sample proteomes; (b) optional verification of the potential candidate protein/peptide biomarkers as identified in step (a) by quantitative mass spectrometric measurement of the potential candidate protein biomarkers in serum, plasma or any other derivatives of blood, or blood itself sample proteomes derived from healt
    Type: Application
    Filed: June 23, 2014
    Publication date: October 30, 2014
    Applicants: Kantonsspital St. Gallen, ETH ZURICH
    Inventors: Wilhelm KREK, Igor CIMA, Rudolf AEBERSOLD, Ralph SCHIESS, Thomas CERNY, Silke GILLESSEN
  • Publication number: 20110065605
    Abstract: The invention relates to a method for the determination of a cancer diagnostic/therapeutic biomarker assay and drug-targets including the following steps: (a) identification of potential candidate protein/peptide biomarkers and drug-targets based on the measurement of protein/peptide constituent concentrations in tissue sample proteomes as well as serum, plasma or any other derivatives of blood, or blood itself sample proteomes derived from healthy non-human mammalian individuals as well as from cancerous non-human mammalian individuals and qualitatively selecting as potential candidate protein/peptide biomarkers those which show a pronounced differential behaviour between healthy and cancerous sample proteomes; (b) optional verification of the potential candidate protein/peptide biomarkers as identified in step (a) by quantitative mass spectrometric measurement of the potential candidate protein biomarkers in serum, plasma or any other derivatives of blood, or blood itself sample proteomes derived from healt
    Type: Application
    Filed: May 12, 2009
    Publication date: March 17, 2011
    Applicants: ETH ZURICH, KANTONSSPITAL ST. GALLEN
    Inventors: Wilhelm Krek, Igor Cima, Rudolf Aebersold, Ralph Schiess, Thomas Cerny, Silke Gillessen