Patents by Inventor Ralph T. Scaduto

Ralph T. Scaduto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9897520
    Abstract: Sample preparation device that allows for a complete bind, wash, elute, buffer-exchange and concentration process to be carried out without sample transfer between multiple devices. The device includes a reservoir, a column for holding chromatography media, a holder region for holding a filtration device, and an outlet. The filtration device plugs into the holder region of the centrifugal device, and the assembly can be placed in an optional holder. The assembly, with or without the optional holder, can be placed in a conventional centrifuge tube for centrifugation. The entire bind, wash, elute, buffer exchange and concentration steps can be carried out with the apparatus without any pipette transfers (and the associated sample losses. The sample preparation device also can be used for binding and washing steps, in which case the filtration device is not needed, and for buffer exchange and concentration steps, in which case the media is not needed.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: February 20, 2018
    Assignee: EMD Millipore Corporation
    Inventors: Christopher A. Scott, Timothy K. Nadler, Kurt Greenizen, Louis Bonhomme, Sara D. Gutierrez, Masaharu Mabuchi, David Briggs, Phillip Clark, Ralph T. Scaduto
  • Publication number: 20160103045
    Abstract: Sample preparation device that allows for a complete bind, wash, elute, buffer-exchange and concentration process to be carried out without sample transfer between multiple devices. The device includes a reservoir, a column for holding chromatography media, a holder region for holding a filtration device, and an outlet. The filtration device plugs into the holder region of the centrifugal device, and the assembly can be placed in an optional holder. The assembly, with or without the optional holder, can be placed in a conventional centrifuge tube for centrifugation. The entire bind, wash, elute, buffer exchange and concentration steps can be carried out with the apparatus without any pipette transfers (and the associated sample losses. The sample preparation device also can be used for binding and washing steps, in which case the filtration device is not needed, and for buffer exchange and concentration steps, in which case the media is not needed.
    Type: Application
    Filed: December 18, 2015
    Publication date: April 14, 2016
    Inventors: Christopher A. Scott, Timothy K. Nadler, Kurt Greenizen, Louis Bonhomme, Sara D. Gutierrez, Masaharu Mabuchi, David Briggs, Phillip Clark, Ralph T. Scaduto
  • Patent number: 9304070
    Abstract: Sample preparation device that allows for a complete bind, wash, elute, buffer-exchange and concentration process to be carried out without sample transfer between multiple devices. The device includes a reservoir, a column for holding chromatography media, a holder region for holding a filtration device, and an outlet. The filtration device plugs into the holder region of the centrifugal device, and the assembly can be placed in an optional holder. The assembly, with or without the optional holder, can be placed in a conventional centrifuge tube for centrifugation. The entire bind, wash, elute, buffer exchange and concentration steps can be carried out with the apparatus without any pipette transfers (and the associated sample losses. The sample preparation device also can be used for binding and washing steps, in which case the filtration device is not needed, and for buffer exchange and concentration steps, in which case the media is not needed.
    Type: Grant
    Filed: June 27, 2012
    Date of Patent: April 5, 2016
    Assignee: EMD Millipore Corporation
    Inventors: Christopher A. Scott, Timothy K. Nadler, Kurt Greenizen, Louis Bonhomme, Sara D. Gutierrez, Masaharu Mabuchi, David Briggs, Phillip Clark, Ralph T. Scaduto
  • Patent number: 9103756
    Abstract: Sample preparation device that allows for a complete bind, wash, elute, buffer-exchange and concentration process to be carried out without sample transfer between multiple devices. The device includes a reservoir, a column for holding chromatography media, a holder region for holding a filtration device, and an outlet. The filtration device plugs into the holder region of the centrifugal device, and the assembly can be placed in an optional holder. The assembly, with or without the optional holder, can be placed in a conventional centrifuge tube for centrifugation. The entire bind, wash, elute, buffer exchange and concentration steps can be carried out with the apparatus without any pipette transfers (and the associated sample losses. The sample preparation device also can be used for binding and washing steps, in which case the filtration device is not needed, and for buffer exchange and concentration steps, in which case the media is not needed.
    Type: Grant
    Filed: September 19, 2013
    Date of Patent: August 11, 2015
    Assignee: EMD Millipore Corporation
    Inventors: Christopher A. Scott, Timothy K. Nadler, Kurt Greenizen, Louis Bonhomme, Sara D. Gutierrez, Masaharu Mabuchi, David Briggs, Phillip Clark, Ralph T. Scaduto
  • Publication number: 20140017151
    Abstract: Sample preparation device that allows for a complete bind, wash, elute, buffer-exchange and concentration process to be carried out without sample transfer between multiple devices. The device includes a reservoir, a column for holding chromatography media, a holder region for holding a filtration device, and an outlet. The filtration device plugs into the holder region of the centrifugal device, and the assembly can be placed in an optional holder. The assembly, with or without the optional holder, can be placed in a conventional centrifuge tube for centrifugation. The entire bind, wash, elute, buffer exchange and concentration steps can be carried out with the apparatus without any pipette transfers (and the associated sample losses. The sample preparation device also can be used for binding and washing steps, in which case the filtration device is not needed, and for buffer exchange and concentration steps, in which case the media is not needed.
    Type: Application
    Filed: September 19, 2013
    Publication date: January 16, 2014
    Applicant: EMD Millipore Corporation
    Inventors: Christopher A. Scott, Timothy K. Nadler, Kurt Greenizen, Louis Bonhomme, Sara D. Gutierrez, Masaharu Mabuchi, David Briggs, Phillip Clark, Ralph T. Scaduto
  • Publication number: 20130017620
    Abstract: Sample preparation device that allows for a complete bind, wash, elute, buffer-exchange and concentration process to be carried out without sample transfer between multiple devices. The device includes a reservoir, a column for holding chromatography media, a holder region for holding a filtration device, and an outlet. The filtration device plugs into the holder region of the centrifugal device, and the assembly can be placed in an optional holder. The assembly, with or without the optional holder, can be placed in a conventional centrifuge tube for centrifugation. The entire bind, wash, elute, buffer exchange and concentration steps can be carried out with the apparatus without any pipette transfers (and the associated sample losses. The sample preparation device also can be used for binding and washing steps, in which case the filtration device is not needed, and for buffer exchange and concentration steps, in which case the media is not needed.
    Type: Application
    Filed: June 27, 2012
    Publication date: January 17, 2013
    Applicant: EMD MILLIPORE CORPORATION
    Inventors: Christopher A. Scott, Timothy K. Nadler, Kurt Greenizen, Louis Bonhomme, Sara D. Gutierrez, Masaharu Mabuchi, David Briggs, Phillip Clark, Ralph T. Scaduto