Patents by Inventor Ralph T. Scaduto
Ralph T. Scaduto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9897520Abstract: Sample preparation device that allows for a complete bind, wash, elute, buffer-exchange and concentration process to be carried out without sample transfer between multiple devices. The device includes a reservoir, a column for holding chromatography media, a holder region for holding a filtration device, and an outlet. The filtration device plugs into the holder region of the centrifugal device, and the assembly can be placed in an optional holder. The assembly, with or without the optional holder, can be placed in a conventional centrifuge tube for centrifugation. The entire bind, wash, elute, buffer exchange and concentration steps can be carried out with the apparatus without any pipette transfers (and the associated sample losses. The sample preparation device also can be used for binding and washing steps, in which case the filtration device is not needed, and for buffer exchange and concentration steps, in which case the media is not needed.Type: GrantFiled: December 18, 2015Date of Patent: February 20, 2018Assignee: EMD Millipore CorporationInventors: Christopher A. Scott, Timothy K. Nadler, Kurt Greenizen, Louis Bonhomme, Sara D. Gutierrez, Masaharu Mabuchi, David Briggs, Phillip Clark, Ralph T. Scaduto
-
Publication number: 20160103045Abstract: Sample preparation device that allows for a complete bind, wash, elute, buffer-exchange and concentration process to be carried out without sample transfer between multiple devices. The device includes a reservoir, a column for holding chromatography media, a holder region for holding a filtration device, and an outlet. The filtration device plugs into the holder region of the centrifugal device, and the assembly can be placed in an optional holder. The assembly, with or without the optional holder, can be placed in a conventional centrifuge tube for centrifugation. The entire bind, wash, elute, buffer exchange and concentration steps can be carried out with the apparatus without any pipette transfers (and the associated sample losses. The sample preparation device also can be used for binding and washing steps, in which case the filtration device is not needed, and for buffer exchange and concentration steps, in which case the media is not needed.Type: ApplicationFiled: December 18, 2015Publication date: April 14, 2016Inventors: Christopher A. Scott, Timothy K. Nadler, Kurt Greenizen, Louis Bonhomme, Sara D. Gutierrez, Masaharu Mabuchi, David Briggs, Phillip Clark, Ralph T. Scaduto
-
Patent number: 9304070Abstract: Sample preparation device that allows for a complete bind, wash, elute, buffer-exchange and concentration process to be carried out without sample transfer between multiple devices. The device includes a reservoir, a column for holding chromatography media, a holder region for holding a filtration device, and an outlet. The filtration device plugs into the holder region of the centrifugal device, and the assembly can be placed in an optional holder. The assembly, with or without the optional holder, can be placed in a conventional centrifuge tube for centrifugation. The entire bind, wash, elute, buffer exchange and concentration steps can be carried out with the apparatus without any pipette transfers (and the associated sample losses. The sample preparation device also can be used for binding and washing steps, in which case the filtration device is not needed, and for buffer exchange and concentration steps, in which case the media is not needed.Type: GrantFiled: June 27, 2012Date of Patent: April 5, 2016Assignee: EMD Millipore CorporationInventors: Christopher A. Scott, Timothy K. Nadler, Kurt Greenizen, Louis Bonhomme, Sara D. Gutierrez, Masaharu Mabuchi, David Briggs, Phillip Clark, Ralph T. Scaduto
-
Patent number: 9103756Abstract: Sample preparation device that allows for a complete bind, wash, elute, buffer-exchange and concentration process to be carried out without sample transfer between multiple devices. The device includes a reservoir, a column for holding chromatography media, a holder region for holding a filtration device, and an outlet. The filtration device plugs into the holder region of the centrifugal device, and the assembly can be placed in an optional holder. The assembly, with or without the optional holder, can be placed in a conventional centrifuge tube for centrifugation. The entire bind, wash, elute, buffer exchange and concentration steps can be carried out with the apparatus without any pipette transfers (and the associated sample losses. The sample preparation device also can be used for binding and washing steps, in which case the filtration device is not needed, and for buffer exchange and concentration steps, in which case the media is not needed.Type: GrantFiled: September 19, 2013Date of Patent: August 11, 2015Assignee: EMD Millipore CorporationInventors: Christopher A. Scott, Timothy K. Nadler, Kurt Greenizen, Louis Bonhomme, Sara D. Gutierrez, Masaharu Mabuchi, David Briggs, Phillip Clark, Ralph T. Scaduto
-
Publication number: 20140017151Abstract: Sample preparation device that allows for a complete bind, wash, elute, buffer-exchange and concentration process to be carried out without sample transfer between multiple devices. The device includes a reservoir, a column for holding chromatography media, a holder region for holding a filtration device, and an outlet. The filtration device plugs into the holder region of the centrifugal device, and the assembly can be placed in an optional holder. The assembly, with or without the optional holder, can be placed in a conventional centrifuge tube for centrifugation. The entire bind, wash, elute, buffer exchange and concentration steps can be carried out with the apparatus without any pipette transfers (and the associated sample losses. The sample preparation device also can be used for binding and washing steps, in which case the filtration device is not needed, and for buffer exchange and concentration steps, in which case the media is not needed.Type: ApplicationFiled: September 19, 2013Publication date: January 16, 2014Applicant: EMD Millipore CorporationInventors: Christopher A. Scott, Timothy K. Nadler, Kurt Greenizen, Louis Bonhomme, Sara D. Gutierrez, Masaharu Mabuchi, David Briggs, Phillip Clark, Ralph T. Scaduto
-
Publication number: 20130017620Abstract: Sample preparation device that allows for a complete bind, wash, elute, buffer-exchange and concentration process to be carried out without sample transfer between multiple devices. The device includes a reservoir, a column for holding chromatography media, a holder region for holding a filtration device, and an outlet. The filtration device plugs into the holder region of the centrifugal device, and the assembly can be placed in an optional holder. The assembly, with or without the optional holder, can be placed in a conventional centrifuge tube for centrifugation. The entire bind, wash, elute, buffer exchange and concentration steps can be carried out with the apparatus without any pipette transfers (and the associated sample losses. The sample preparation device also can be used for binding and washing steps, in which case the filtration device is not needed, and for buffer exchange and concentration steps, in which case the media is not needed.Type: ApplicationFiled: June 27, 2012Publication date: January 17, 2013Applicant: EMD MILLIPORE CORPORATIONInventors: Christopher A. Scott, Timothy K. Nadler, Kurt Greenizen, Louis Bonhomme, Sara D. Gutierrez, Masaharu Mabuchi, David Briggs, Phillip Clark, Ralph T. Scaduto