Patents by Inventor Ralph William de Vere White

Ralph William de Vere White has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for cytotoxic chemotherapy-based predictive assays
    Patent number: 11474106
    Abstract: The invention relates to methods, systems and kits for determining therapeutic effectiveness or toxicity of cancer-treating compounds that incorporate into or bind to DNA. In particular, the invention is directed to methods, systems and kits for predicting a patient's treatment outcome after administration of a microdose of therapeutic composition to the patient. The methods provides physicians with a diagnostic tool to segregate cancer patients into differential populations that have a higher or lower chance of responding to a particular therapeutic treatment.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: October 18, 2022
    Assignee: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventors: Paul Henderson, George D. Cimino, Chong-Xian Pan, Ralph William de Vere White, Maike Zimmermann, Kenneth W. Turteltaub
  • METHODS, SYSTEMS AND KITS FOR CYTOTOXIC CHEMOTHERAPY-BASED PREDICTIVE ASSAYS
    Publication number: 20180209984
    Abstract: The invention relates to methods, systems and kits for determining therapeutic effectiveness or toxicity of cancer-treating compounds that incorporate into or bind to DNA. In particular, the invention is directed to methods, systems and kits for predicting a patient's treatment outcome after administration of a microdose of therapeutic composition to the patient. The methods provides physicians with a diagnostic tool to segregate cancer patients into differential populations that have a higher or lower chance of responding to a particular therapeutic treatment.
    Type: Application
    Filed: July 7, 2016
    Publication date: July 26, 2018
    Inventors: Paul Henderson, George D. Cimino, Chong-Xian Pan, Ralph William de Vere White, Maike Zimmermann, Kenneth W. Turteltaub