Patents by Inventor Ram Chander Aryan

Ram Chander Aryan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PREPARATION OF ENZALUTAMIDE
    Publication number: 20170174635
    Abstract: The present invention provides a process for the preparation of enzalutamide.
    Type: Application
    Filed: January 30, 2015
    Publication date: June 22, 2017
    Inventors: Ramendra Singh RATHORE, Venugopal Venkatarama DURVASULA, Amit SHARMA, Ram Chander ARYAN
  • PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF ENZALUTAMIDE
    Publication number: 20160318875
    Abstract: The present invention provides processes for the preparation of enzalutamide.
    Type: Application
    Filed: December 9, 2014
    Publication date: November 3, 2016
    Inventors: Ramendra Singh RATHORE, Venugopal Venkatarama DURVASULA, Amit SHARMA, Ram Chander ARYAN
  • PROCESS FOR THE PREPARATION OF ENZALUTAMIDE
    Publication number: 20160251316
    Abstract: The present invention provides a process for the preparation of enzalutamide.
    Type: Application
    Filed: October 30, 2014
    Publication date: September 1, 2016
    Inventors: Ramendra Singh RATHORE, Venugopal Venkatarama DURVASULA, Amit SHARMA, Ram Chander ARYAN
  • SAXAGLIPTIN SALTS
    Publication number: 20150329489
    Abstract: The present invention provides saxagliptin bisulphate, saxagliptin acetate, saxagliptin oxalate, saxagliptin bicarbonate, and saxagliptin carbonate, their polymorphic forms, processes for their preparation, and pharmaceutical compositions thereof.
    Type: Application
    Filed: July 2, 2013
    Publication date: November 19, 2015
    Inventors: Ram Chander ARYAN, Ashwani Kumar SINGH, Amit SHARMA, Ramendra Singh RATHORE
  • Process for the preparation of asenapine maleate
    Patent number: 9145421
    Abstract: The present invention provides a process for the preparation of asenapine maleate of Formula (I), comprising: intra-molecular cyclization of the intermediate of Formula (II) to obtain the intermediate of Formula (III) using aluminium halide.
    Type: Grant
    Filed: July 17, 2012
    Date of Patent: September 29, 2015
    Assignee: RANBAXY LABORATORIES LIMITED
    Inventors: Ram Chander Aryan, Anamika Mishra, Pudi Giri Jagannadha Naidu, Ramnik Sharma
  • PROCESS FOR THE PREPARATION OF ASENAPINE MALEATE
    Publication number: 20150112083
    Abstract: The present invention provides a process for the preparation of asenapine maleate of Formula (I), comprising: intra-molecular cyclization of the intermediate of Formula (II) to obtain the intermediate of Formula (III) using aluminium halide.
    Type: Application
    Filed: July 17, 2012
    Publication date: April 23, 2015
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Ram Chander Aryan, Anamika Mishra, Pudi Giri Jagannadha Naidu, Ramnik Sharma
  • PROCESS FOR THE PREPARATION OF ASENAPINE INTERMEDIATE
    Publication number: 20140336391
    Abstract: The present invention provides a process for the preparation of the asenapine intermediate of Formula (III) using a magnesium-methanol-acetic acid mixture.
    Type: Application
    Filed: November 7, 2012
    Publication date: November 13, 2014
    Inventors: Ramnik Sharma, Senkara Rao Allu, Ram Chander Aryan
  • PROCESS FOR THE PREPARATION OF BORTEZOMIB
    Publication number: 20130085277
    Abstract: The present invention relates to a process for the preparation of bortezomib (Formula I) and its intermediates.
    Type: Application
    Filed: February 9, 2011
    Publication date: April 4, 2013
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Satish Kumar, Venugopal Venkatarama Durvasula, Parendu Dhirajlal Rathod, Ram Chander Aryan
  • Process for the preparation of clopidogrel and its pharmaceutically acceptable salts
    Patent number: 8247558
    Abstract: The present invention provides a process for the preparation of clopidogrel and its pharmaceutically acceptable salts thereof comprises the resolving racemic methyl alpha-5-(4,5,6,7-tetrahydro[3,2-c]thienopyridyl)(2-chlorophenyl)-acetate by the salt formation of methyl alpha-5-(4,5,6,7-tetrahydro[3,2-c]thienopyridyl)(2-chlorophenyl)-acetate with excess levorotatory camphor-10-sulfonic acid to get a maximum yield of camphor sulphonate salt of methyl S-(+)-alpha-5-(4,5,6,7-tetrahydro[3,2-c]thienopyridyl) (2-chlorophenyl)-acetate and transforming the camphor sulphonate salt to clopidogrel or its pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: September 4, 2007
    Date of Patent: August 21, 2012
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Parendn Dhirajlal Rathod, Satish Kumar Aryan, Ram Chander Aryan, Chandra Has Khanduri
  • PROCESS FOR THE PREPARATION OF CLOPIDOGREL HYDROGEN SULPHATE FORM I
    Publication number: 20110263858
    Abstract: The present invention relates to a process for the preparation of Form 1 of (+)-(S)-?-(2-Chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-acetic acid methyl ester hydrogen sulphate commonly known as clopidogrel bisulphate. The present invention further relates to a process for reducing the residual amount of methyl isobutyl ketone and controlling the amount of mesityl oxide in clopidogrel hydrogen sulphate Form 1 by washing with ethyl acetate. Formula (I).
    Type: Application
    Filed: October 20, 2009
    Publication date: October 27, 2011
    Inventors: Satish Kumar Aryan, Parendu Dhirajlal Rathod, Ram Chander Aryan, Chandra Has Khanduri
  • Substituted Pyrrole Derivatives and Their Use as HMG-CO Inhibitors
    Publication number: 20110190369
    Abstract: The present invention relates to substituted pyrrole derivatives, which can be used as 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors. Compounds disclosed herein can function as cholesterol lowering agents and can be used for the treatment of cholesterol-related diseases and related symptoms. Processes for the preparation of disclosed compounds are provided, as well as pharmaceutical compositions containing the disclosed compounds, and methods of treating cholesterol-related diseases and related symptoms.
    Type: Application
    Filed: April 11, 2011
    Publication date: August 4, 2011
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Mohammad SALMAN, Jitendra SATTIGERI, Yatendra KUMAR, Ram Chander ARYAN, Vikram Krishna RAMANATHAN, Anita CHUGH
  • Substituted Pyrrole Derivatives and Their Use as HMG-CO Inhibitors
    Publication number: 20110190296
    Abstract: The present invention relates to substituted pyrrole derivatives, which can be used as 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors. Compounds disclosed herein can function as cholesterol lowering agents and can be used for the treatment of cholesterol-related diseases and related symptoms. Processes for the preparation of disclosed compounds are provided, as well as pharmaceutical compositions containing the disclosed compounds, and methods of treating cholesterol-related diseases and related symptoms.
    Type: Application
    Filed: April 11, 2011
    Publication date: August 4, 2011
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Mohammad SALMAN, Jitendra SATTIGERI, Yatendra KUMAR, Ram Chander ARYAN, Vikram Krishna RAMANATHAN, Anita CHUGH
  • Substituted pyrrole derivatives and their use as HMG-CO inhibitors
    Patent number: 7923467
    Abstract: The present invention relates to substituted pyrrole derivatives, which can be used as 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors. Compounds disclosed herein can function as cholesterol lowering agents and can be used for the treatment of cholesterol-related diseases and related symptoms. Processes for the preparation of disclosed compounds are provided, as well as pharmaceutical compositions containing the disclosed compounds, and methods of treating cholesterol-related diseases and related symptoms.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: April 12, 2011
    Assignee: Ranbaxy Laboratories, Inc.
    Inventors: Mohammad Salman, Jitendra Sattigeri, Yatendra Kumar, Ram Chander Aryan, Vikram Krishna Ramanathan, Anita Chugh
  • Substituted Pyrrole Derivatives And Their Use As HMG-CO Inhibitors
    Publication number: 20100056602
    Abstract: The present invention relates to substituted pyrrole derivatives, which can be used as 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors. Compounds disclosed herein can function as cholesterol lowering agents and can be used for the treatment of cholesterol-related diseases and related symptoms. Processes for the preparation of disclosed compounds are provided, as well as pharmaceutical compositions containing the disclosed compounds, and methods of treating cholesterol-related diseases and related symptoms.
    Type: Application
    Filed: May 28, 2004
    Publication date: March 4, 2010
    Inventors: Mohammad Salman, Jitendra Sattigeri, Yatendra Kumar, Ram Chander Aryan, Vikram Krishna Ramanathan, Anita Chugh
  • PROCESS FOR THE PREPARATION OF CLOPIDOGREL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS
    Publication number: 20100016594
    Abstract: The present invention provides a process for the preparation of clopidogrel and its pharmaceutically acceptable salts thereof comprises the resolving racemic methyl alpha-5-(4,5,6,7-tetrahydro[3,2-c]thienopyridyl)(2-chlorophenyl)-acetate by the salt formation of methyl alpha-5-(4,5,6,7-tetrahydro[3,2-c]thienopyridyl)(2-chlorophenyl)-acetate with excess levorotatory camphor-10-sulfonic acid to get a maximum yield of camphor sulphonate salt of methyl S-(+)-alpha-5-(4,5,6,7-tetrahydro[3,2-e]thienopyridyl)(2-chlorophenyl)-acetate and transforming the camphor sulphonate salt to clopidogrel or its pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: September 4, 2007
    Publication date: January 21, 2010
    Inventors: Parendu Dhirajlal Rathod, Satish Kumar Aryan, Ram Chander Aryan, Chandra Has Khanduri
  • Process for the isolation of crystalline imipenem
    Patent number: 7241885
    Abstract: The present invention relates to a cost effective and industrially advantageous process for the preparation of imipenem of high purity comprising the steps of treating an aqueous solution containing imipenem with an organic solvent, wherein the imipenem is not lyophilized; and isolating the pure crystalline imipenem monohydrate from the reaction mixture thereof.
    Type: Grant
    Filed: May 20, 2002
    Date of Patent: July 10, 2007
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Yatendra Kumar, Neera Tewari, Ram Chander Aryan, Bishwa Prakash Rai
  • Tamsulosin derivative
    Patent number: 7084301
    Abstract: The optically active compound, R (?)-5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-hydroxybenzenesulfonamide in good optical purity, a metabolite of the ?1-adrenergic blocking agent tamsulosin, and methods for the preparation thereof. Pharmaceutical compositions including the optically active compound and methods of treatment comprising administration of an effective ?1-adrenergic antagonistic amount of such compositions to mammals.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: August 1, 2006
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Yatendra Kumar, Ram Chander Aryan, Radhakrishnan Gowri Shankar, Kumar Hari Bhushan, Anita Chugh
  • HMG CoA-reductase inhibitors
    Patent number: 7078430
    Abstract: The invention relates to particular hydroxyl and protected hydroxyl derivatives of compounds known to be useful as HMG CoA-reductase inhibitors. In particular, herein are provided hydroxyl and protected hydroxyl compounds of Formula I and their corresponding lactones.
    Type: Grant
    Filed: May 5, 2003
    Date of Patent: July 18, 2006
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Yatendra Kumar, Ram Chander Aryan, Jitendra Sattigeri, Mohammad Salman, Gowri Shankar, Kumar Hari Bhushan, Bhargav R. Panyda, Ramnik Sharma
  • Tamsulosin derivative
    Patent number: 6894188
    Abstract: The optically active compound, R(?)-5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-hydroxybenzenesulfonamide in good optical purity, a metabolite of the ?1-adrenergic blocking agent tamsulosin, and methods for the preparation thereof. Pharmaceutical compositions including the optically active compound and methods of treatment comprising administration of an effective ?-adrenergic antagonistic amount of such compositions to mammals.
    Type: Grant
    Filed: January 14, 2003
    Date of Patent: May 17, 2005
    Assignee: Ranbaxy Laboratory Limited
    Inventors: Yatendra Kumar, Ram Chander Aryan, Radhakrishnan Gowri Shankar, Kumar Hari Bhushan, Anita Chugh
  • Process for the isolation of crystalline imipenem
    Publication number: 20040242865
    Abstract: The present invention relates to a cost effective and industrially advantageous process for the preparation of imipenem of high purity.
    Type: Application
    Filed: June 17, 2004
    Publication date: December 2, 2004
    Inventors: Yatendra Kumar, Neera Tewari, Ram Chander Aryan, Bishwa Prakash Rai