Abstract: The present disclosure relates to a method of high yielding production of gas vesicle nanoparticles (GVNPs) and genetic tools used for high-yielding GVNPs production. The present disclosure further relates to a method of creating 3D tissue constructs with improved cell viability and proliferation and the resulting 3D tissue constructs. The GVNPs can promote cell growth and proliferation in 3D constructs and are suitable bioinks components for a bioprinter to build 3D structures through 3D printing as well as other applications.

Abstract: The present invention generally relates to a self-charging system for electric vehicles comprises at least one gearbox comprises an input end and an output end mechanically coupled to one of the wheels of a vehicle to the input end to generate a rotational energy with an increased output of one of the torque or speed (RPM) to the output end; an auxiliary generator connected to the output end of the at least one gearbox to convert the rotational energy into electrical energy; a controller equipped with a maximum power point tracker to produce maximum power output; and a charger controller coupled to the maximum power point tracker to charge a batter of the vehicle upon limiting electric current rate of the power output to protect against electrical overload, overcharging, and overvoltage.

Abstract: The present disclosure relates to solid state forms of baloxavir marboxil, processes for preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.

Abstract: Embodiments of the present disclosure describe methods, systems, and compositions for the production of bioplastic from a gaseous substrate containing a carbon source by a two-stage fermentation process. Stage I includes introducing a gaseous substrate comprising CO2 and H2 to a primary bioreactor containing a culture of an acetogenic microorganism, anaerobically fermenting the gaseous substrate under elevated pressure to produce an acid-containing culture medium, and stage II includes aerobically fermenting the acid of the culture medium in a secondary bioreactor containing a culture of a PHA-producing microorganism to produce a polyhydroxyalkanoate (PHA). The culture medium can be suitable for both the first and second stages and enable the primary and secondary bioreactors to be connected in a sustainable continuous system.