Patents by Inventor Ram Paul
Ram Paul has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240016608Abstract: Valve devices, methods of making valve devices, and methods of treating various venous-related conditions, disorders and/or diseases are described. In one embodiment, a valve device includes an expandable support frame and a bioprosthetic valve attached to the support frame. The bioprosthetic valve comprises a leaflet and a contiguous wall portion harvested from a multi-leaflet xenogeneic valve. The contiguous wall portion includes the attachment region where the leaflets attaches to the vessel wall and, in some embodiments, includes the natural margins of attachment between the leaflet and vessel wall.Type: ApplicationFiled: August 8, 2023Publication date: January 18, 2024Applicant: Cook Medical Technologies LLCInventors: Sean Chambers, Ram Paul
-
Publication number: 20230404703Abstract: Medical devices useful in interventional procedures performed under magnetic resonance imaging (MRI) are described herein. A medical device comprises a body member and a marker formed of work-hardened stainless steel attached to the body member. The stainless steel of the marker has an ultimate tensile strength of between about 100 KSI and about 225 KSI. The marker can be attached to the body member in a manner that contributes work to the stainless steel or in a manner that does not contribute work to the stainless steel. Methods of making medical devices, medical imaging methods, and methods of performing interventional medical treatment are also described herein.Type: ApplicationFiled: August 28, 2023Publication date: December 21, 2023Applicant: Cook Medical Technologies LLCInventor: Ram Paul
-
Publication number: 20230380974Abstract: Valve devices, methods of making valve devices, and methods of treating various venous-related conditions, disorders and/or diseases are described. In one embodiment, a valve device includes an expandable support frame and a bioprosthetic valve attached to the support frame. The bioprosthetic valve comprises a leaflet and a contiguous wall portion harvested from a multi-leaflet xenogeneic valve. The contiguous wall portion includes the attachment region where the leaflets attaches to the vessel wall and, in some embodiments, includes the natural margins of attachment between the leaflet and vessel wall.Type: ApplicationFiled: August 8, 2023Publication date: November 30, 2023Applicant: Cook Medical Technologies LLCInventors: Sean Chambers, Ram Paul
-
Publication number: 20230338149Abstract: Valve devices, methods of making valve devices, and methods of treating various venous-related conditions, disorders and/or diseases are described. In one embodiment, a valve device includes an expandable support frame and a bioprosthetic valve attached to the support frame. The bioprosthetic valve comprises a leaflet and a contiguous wall portion harvested from a multi-leaflet xenogeneic valve. The contiguous wall portion includes the attachment region where the leaflets attaches to the vessel wall and, in some embodiments, includes the natural margins of attachment between the leaflet and vessel wall.Type: ApplicationFiled: July 6, 2023Publication date: October 26, 2023Applicant: Cook Medical Technologies LLCInventors: Sean Chambers, Ram Paul
-
Patent number: 11737851Abstract: Medical devices useful in interventional procedures performed under magnetic resonance imaging (MRI) are described herein. A medical device comprises a body member and a marker formed of work-hardened stainless steel attached to the body member. The stainless steel of the marker has an ultimate tensile strength of between about 100 KSI and about 225 KSI. The marker can be attached to the body member in a manner that contributes work to the stainless steel or in a manner that does not contribute work to the stainless steel. Methods of making medical devices, medical imaging methods, and methods of performing interventional medical treatment are also described herein.Type: GrantFiled: June 27, 2019Date of Patent: August 29, 2023Assignee: Cook Medical Technologies LLCInventor: Ram Paul
-
Patent number: 11717408Abstract: Valve devices, methods of making valve devices, and methods of treating various venous-related conditions, disorders and/or diseases are described. In one embodiment, a valve device includes an expandable support frame and a bioprosthetic valve attached to the support frame. The bioprosthetic valve comprises a leaflet and a contiguous wall portion harvested from a multi-leaflet xenogeneic valve. The contiguous wall portion includes the attachment region where the leaflets attaches to the vessel wall and, in some embodiments, includes the natural margins of attachment between the leaflet and vessel wall.Type: GrantFiled: July 10, 2020Date of Patent: August 8, 2023Assignee: Cook Medical Technologies LLCInventors: Sean Chambers, Ram Paul
-
Patent number: 11325877Abstract: A process for the recovery of ethylene glycol from an aqueous stream comprising ethylene glycol is disclosed. The process comprises (a) subjecting an aqueous stream 5 comprising ethylene glycol to an evaporation step in a multiple-effect evaporator to obtain a concentrated stream comprising ethylene glycol; (b) subjecting said concentrated stream comprising ethylene glycol to a first dehydration step in a first dehydrator 10 operating at an overhead pressure in the range of 0 barg (bar gauge) to 4 barg (bar gauge) to obtain a partially dehydrated ethylene glycol stream, and (c) subjecting said partially dehydrated ethylene glycol stream to a second dehydration step in a second dehydrator operating under 15 vacuum to obtain a dehydrated ethylene glycol stream.Type: GrantFiled: November 20, 2018Date of Patent: May 10, 2022Assignee: SHELL USA, INC.Inventors: Ram Paul Bajaj, Peter Molenaar
-
Publication number: 20200337844Abstract: Valve devices, methods of making valve devices, and methods of treating various venous-related conditions, disorders and/or diseases are described. In one embodiment, a valve device includes an expandable support frame and a bioprosthetic valve attached to the support frame. The bioprosthetic valve comprises a leaflet and a contiguous wall portion harvested from a multi-leaflet xenogeneic valve. The contiguous wall portion includes the attachment region where the leaflets attaches to the vessel wall and, in some embodiments, includes the natural margins of attachment between the leaflet and vessel wall.Type: ApplicationFiled: July 10, 2020Publication date: October 29, 2020Applicant: Cook Medical Technologies LLCInventors: Sean Chambers, Ram Paul
-
Publication number: 20200299215Abstract: A process for the recovery of ethylene glycol from an aqueous stream comprising ethylene glycol is disclosed. The process comprises (a) subjecting an aqueous stream 5 comprising ethylene glycol to an evaporation step in a multiple-effect evaporator to obtain a concentrated stream comprising ethylene glycol; (b) subjecting said concentrated stream comprising ethylene glycol to a first dehydration step in a first dehydrator 10 operating at an overhead pressure in the range of 0 barg (bar gauge) to 4 barg (bar gauge) to obtain a partially dehydrated ethylene glycol stream, and (c) subjecting said partially dehydrated ethylene glycol stream to a second dehydration step in a second dehydrator operating under 15 vacuum to obtain a dehydrated ethylene glycol stream.Type: ApplicationFiled: November 20, 2018Publication date: September 24, 2020Inventors: Ram Paul BAJAJ, Peter MOLENAAR
-
Patent number: 10722365Abstract: Valve devices, methods of making valve devices, and methods of treating various venous-related conditions, disorders and/or diseases are described. In one embodiment, a valve device includes an expandable support frame and a bioprosthetic valve attached to the support frame. The bioprosthetic valve comprises a leaflet and a contiguous wall portion harvested from a multi-leaflet xenogeneic valve. The contiguous wall portion includes the attachment region where the leaflets attaches to the vessel wall and, in some embodiments, includes the natural margins of attachment between the leaflet and vessel wall.Type: GrantFiled: January 25, 2017Date of Patent: July 28, 2020Assignee: Cook Medical Technologies LLCInventors: Sean Chambers, Ram Paul, Norman Jaffe
-
Publication number: 20200000545Abstract: Medical devices useful in interventional procedures performed under magnetic resonance imaging (MRI) are described herein. A medical device comprises a body member and a marker formed of work-hardened stainless steel attached to the body member. The stainless steel of the marker has an ultimate tensile strength of between about 100 KSI and about 225 KSI. The marker can be attached to the body member in a manner that contributes work to the stainless steel or in a manner that does not contribute work to the stainless steel. Methods of making medical devices, medical imaging methods, and methods of performing interventional medical treatment are also described herein.Type: ApplicationFiled: June 27, 2019Publication date: January 2, 2020Applicant: Cook Medical Technologies LLCInventor: Ram Paul
-
Patent number: 10111666Abstract: A prosthesis including a self-expanding stent, a graft body, and one or more sleeves is disclosed, in addition to methods of treatment using the prosthesis. The proximal and distal ends of the prosthesis may include one or more sleeves and one or more barbs. The sleeves may be removable or dissolvable, for example, upon exposure to an activating agent. The prosthesis may be used to treat lacerated vessels and transected vessels.Type: GrantFiled: October 21, 2015Date of Patent: October 30, 2018Assignee: Cook Medical Technologies LLCInventors: Ram Paul, Jr., Christopher D. Bosel
-
Publication number: 20170128212Abstract: Valve devices, methods of making valve devices, and methods of treating various venous-related conditions, disorders and/or diseases are described. In one embodiment, a valve device includes an expandable support frame and a bioprosthetic valve attached to the support frame. The bioprosthetic valve comprises a leaflet and a contiguous wall portion harvested from a multi-leaflet xenogeneic valve. The contiguous wall portion includes the attachment region where the leaflets attaches to the vessel wall and, in some embodiments, includes the natural margins of attachment between the leaflet and vessel wall.Type: ApplicationFiled: January 25, 2017Publication date: May 11, 2017Inventors: Sean Chambers, Ram Paul, Norman Jaffe
-
Publication number: 20160120548Abstract: A prosthesis including a self-expanding stent, a graft body, and one or more sleeves is disclosed, in addition to methods of treatment using the prosthesis. The proximal and distal ends of the prosthesis may include one or more sleeves and one or more barbs. The sleeves may be removable or dissolvable, for example, upon exposure to an activating agent. The prosthesis may be used to treat lacerated vessels and transected vessels.Type: ApplicationFiled: October 21, 2015Publication date: May 5, 2016Applicant: COOK MEDICAL TECHNOLOGIES LLCInventors: Ram Paul, JR., Christopher D. Bosel
-
Patent number: 9023074Abstract: An occlusion device has a covering attached to a support frame that includes a disc-shaped member and a crossbar that extends across a central opening defined by the disc-shaped member. The occlusion device has a first, or deployed, configuration in which the crossbar defines a curve that extends from the disc-shaped member, and a second, or resting, configuration in which the disc-shaped member and the crossbar lie substantially in a single plane. Each of the disc-shaped member and the crossbar include a core wire that extends through a lumen of a coil multiple times.Type: GrantFiled: May 1, 2012Date of Patent: May 5, 2015Assignees: Cook Medical Technologies LLC, Oregon Health and Science UniversityInventors: Elizabeth Theobald, James R. Randolph, Dusan Pavcnik, Frederick Keller, Brad Shirley, Sean Chambers, Ram Paul, Rodney Thurman, Michael Deckard
-
Publication number: 20130116720Abstract: An occlusion device has a covering attached to a support frame that includes a disc-shaped member and a crossbar that extends across a central opening defined by the disc-shaped member. The occlusion device has a first, or deployed, configuration in which the crossbar defines a curve that extends from the disc-shaped member, and a second, or resting, configuration in which the disc-shaped member and the crossbar lie substantially in a single plane. Each of the disc-shaped member and the crossbar include a core wire that extends through a lumen of a coil multiple times.Type: ApplicationFiled: May 1, 2012Publication date: May 9, 2013Inventors: Elizabeth Theobald, JR Randolph, Dusan Pavcnik, Frederick Keller, Brad Shirley, Sean Chambers, Ram Paul, Rodney M. Thurman, Michael Deckard
-
Publication number: 20090105813Abstract: Valve devices, methods of making valve devices, and methods of treating various venous-related conditions, disorders and/or diseases are described. In one embodiment, a valve device includes an expandable support frame and a bioprosthetic valve attached to the support frame. The bioprosthetic valve comprises a leaflet and a contiguous wall portion harvested from a multi-leaflet xenogeneic valve. The contiguous wall portion includes the attachment region where the leaflets attaches to the vessel wall and, in some embodiments, includes the natural margins of attachment between the leaflet and vessel wall.Type: ApplicationFiled: October 16, 2008Publication date: April 23, 2009Inventors: Sean Chambers, Ram Paul, Norman Jaffe
-
Publication number: 20080097586Abstract: An valve prosthesis, such as an artificial venous valve, having a support frame and leaf structure comprising one or more leaflets in which the outer edge of each leaflet engages the inner circumference of the bodily passageway along a serpentine path urged against the passageway by an expandable frame, while the inner edges move in response to fluid to restrict retrograde flow. Optionally, one or more elements can extend from the support frame/leaf structure to provide centering support and/or protection from the leaflet adhering to the vessel wall. In one embodiment, the centering support structure comprises a second or third expandable frames attached to and extending from the proximal and/or distal ends of main valve structure and support frame. In another embodiment, one or more support elements extend outward from the valve support frame to engage the vessel wall to provide greater longitudinal stability.Type: ApplicationFiled: October 31, 2007Publication date: April 24, 2008Inventors: DUSAN PAVCNIK, THOMAS OSBORNE, BRIAN Case, JACOB FLAGLE, MICHAEL GARRISON, RAM PAUL, ANDREW HOFFA, RAYMOND LEONARD, DARIN SCHAEFFER, RICHARD SISKEN
-
Publication number: 20080051737Abstract: A medical device is adapted for at least partial implantation into a body and includes first and second sections along the length of the device. A first therapeutic agent is associated with the first section and a second therapeutic agent is associated with the second section. The first therapeutic agent can be one or more antiproliferative, such as paclitaxel, a paclitaxel derivative, or a paclitaxel pro-drug, anti-coagulant, antithrombotic, thrombolytic, fibrinolytic, or combination thereof. The second therapeutic agent can be one or more antimicrobials, such as one or more antibiotics. Each of the first and second therapeutic agents can either be posited on one or more surfaces of the respective section, or impregnated within the section. The device can include a separator to space the first and second sections. A method of making a medical device and a method of establishing access to a vessel within a body are also provided.Type: ApplicationFiled: October 31, 2007Publication date: February 28, 2008Applicant: Cook IncorporatedInventors: Ram Paul, Daniel Sirota, Paul Amarant
-
METHODS OF TREATING VENOUS VALVE RELATED CONDITIONS WITH A FLOW-MODIFYING IMPLANTABLE MEDICAL DEVICE
Publication number: 20080051879Abstract: Implantable medical devices adapted to modify fluid flow within a body vessel are provided herein. The medical devices may include a fluid flow restricting channel configured to reduce longitudinal fluid flow in a retrograde direction or in an antegrade direction. Preferably, the medical devices are flow-modifying devices that reduce fluid flow through the medical device to a greater extent in a retrograde direction than in an antegrade direction. Methods of treatment comprising the step of implanting a flow-modifying medical device within a body vessel are also provided. Flow-modifying devices are useful, for example, in treating venous valve related conditions.Type: ApplicationFiled: August 23, 2007Publication date: February 28, 2008Applicant: Cook IncorporatedInventors: Brian Case, Gary Shirley, Ram Paul, Jacob Flagle