Patents by Inventor Ram Prakash Sharma

Ram Prakash Sharma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12181196
    Abstract: An evaporator assembly for an ice machine is disclosed. The assembly comprises of a frame, a plurality of first cooling surfaces that are spaced at a distance and extend in a first direction within the frame. The assembly also includes a plurality of second cooling surfaces which extend in a second direction perpendicular to the first direction within the frame. An intersection of the plurality of first and second cooling surfaces defines a plurality of ice forming blocks. Further, at least one conductive wall having a first surface and a second surface is provided. The first surface of the conductive wall is configured to accommodate the plurality of ice forming blocks and the second surface of the conductive wall is configured to come in contact with refrigerant or defrost fluid.
    Type: Grant
    Filed: September 24, 2020
    Date of Patent: December 31, 2024
    Inventors: Ram Prakash Sharma, Vinay Sharma
  • Publication number: 20240077242
    Abstract: A conductive protrusion assembly (100) is disclosed. The conductive protrusion assembly (100) includes a conductive cup (1) defining a chamber (C). The conductive cup (1) is supportable by a support plate (8) of the evaporator (101). A conductive lid (2) is fixed within the chamber (C), dividing the chamber into a cooling section (A) and an insulating section (B) where, the insulating section (B) of the conductive cup (1) is packed with an insulation material. The conductive lid (2) is defined with an inlet port (15a) and an outlet port (15b) for circulate a cooling fluid through the cooling section (A) and the insulating section (B) is defined with a flow passage to allow flow of a defrost fluid. The conductive protrusion assembly (100) with an insulating section (B) and a cooling section (A) enables spherical shaped ice blocks (7) to be produced without the use of a mould.
    Type: Application
    Filed: May 11, 2021
    Publication date: March 7, 2024
    Inventors: Ram Prakash Sharma, Vinay Sharma
  • Publication number: 20230400239
    Abstract: An evaporator assembly for an ice making machine is disclosed. The evaporator assembly includes a first metal plate and a second metal plate accommodating a refrigerant tube. The first and second metal plates are defined with a plurality of projections (1x and 2x) extending from a first major surface. The plurality of projections (1x and 2x) defines a slot. The slots defined in the second major surface of first and second metal plates comprise a first connector and a second connector, respectively. At least one of the first metal plate and the second metal plate is movable relative to the other such that the first connector and second connector engage with each other secure the first metal plate and the second metal palate.
    Type: Application
    Filed: June 3, 2021
    Publication date: December 14, 2023
    Inventors: RAM PRAKASH SHARMA, VINAY SHARMA
  • Patent number: 11333417
    Abstract: The present disclosure discloses, an evaporator assembly for a vertical flow type ice-making machine. The assembly comprising a plurality of tubes for circulating a refrigerant, and a plurality of conductive protrusions thermally coupled to and extending the plurality of tubes. Each of the plurality of conductive protrusions defines an ice-making region. The assembly also includes a non-conductive plate arranged adjacent to the plurality of tubes. The non-conductive plate is defined with a provision to accommodate the plurality of conductive protrusions which exchanges heat with the refrigerant flowing through the plurality of tubes and forms the ice layer by layer, and shape of at least one surface of the ice is defined by the non-conductive plate. The configuration of the assembly produces ice in the form of individual ice-cubes of a specific shape and size, and thereby improves the efficiency of the machine and ice-making process.
    Type: Grant
    Filed: November 27, 2018
    Date of Patent: May 17, 2022
    Inventors: Ram Prakash Sharma, Vinay Sharma
  • Patent number: 11280532
    Abstract: Disclosed is an evaporator assembly for a horizontal type ice making machine. The evaporator assembly includes a plurality of tubes for circulating a refrigerant; a plurality of conductive protrusions, which are thermally coupled to and extending from each of the plurality of tubes; and a non-conductive plate, which is arranged adjacent to the plurality of tubes. The non-conductive plate is defined with a plurality of moulds, wherein each of the plurality of moulds is defined with a provision to receive one of the plurality of conductive protrusions. Each of the plurality of tubes includes a hemispherical structure, configured to enclose a top portion of the mould. The configuration of the evaporator assembly facilitates fast and efficient formation of ice, and there improves the efficiency of the ice making machine.
    Type: Grant
    Filed: November 23, 2018
    Date of Patent: March 22, 2022
    Inventor: Ram Prakash Sharma
  • Publication number: 20220034569
    Abstract: An evaporator assembly for an ice machine is disclosed. The assembly comprises of a frame, a plurality of first cooling surfaces that are spaced at a distance and extend in a first direction within the frame. The assembly also includes a plurality of second cooling surfaces which extend in a second direction perpendicular to the first direction within the frame. An intersection of the plurality of first and second cooling surfaces defines a plurality of ice forming blocks. Further, at least one conductive wall having a first surface and a second surface is provided. The first surface of the conductive wall is configured to accommodate the plurality of ice forming blocks and the second surface of the conductive wall is configured to come in contact with refrigerant or defrost fluid.
    Type: Application
    Filed: September 24, 2020
    Publication date: February 3, 2022
    Inventors: Ram Prakash SHARMA, Vinay SHARMA
  • Patent number: 11131494
    Abstract: An ice-machine rotatable assembly and housing, comprising a first side wall defining a first elongate slot extending from an edge of the first side wall, and the rotatable assembly comprising: a rotatable member configured to move liquid toward an ice former mounted with respect to the housing. The rotatable member including a first connecting part towards a first end of the rotatable member; and a first slide plate having a rail and a first side panel extending along a length of the rail of the first slide plate. The rail of the first slide plate being configured to be at least partially received by the first elongate slot, wherein: the first connecting part of the rotatable member is moveable along the elongate slot to position the rotatable member in the installed position. The first slide plate is mountable with its rail at least partially received by the first elongate slot.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: September 28, 2021
    Inventors: Ram Prakash Sharma, Vinay Sharma
  • Publication number: 20210199363
    Abstract: Disclosed is an evaporator assembly for a horizontal type ice making machine. The evaporator assembly includes a plurality of tubes for circulating a refrigerant; a plurality of conductive protrusions, which are thermally coupled to and extending from each of the plurality of tubes; and a non-conductive plate, which is arranged adjacent to the plurality of tubes. The non-conductive plate is defined with a plurality of moulds, wherein each of the plurality of moulds is defined with a provision to receive one of the plurality of conductive protrusions. Each of the plurality of tubes includes a hemispherical structure, configured to enclose a top portion of the mould. The configuration of the evaporator assembly facilitates fast and efficient formation of ice, and there improves the efficiency of the ice making machine.
    Type: Application
    Filed: November 23, 2018
    Publication date: July 1, 2021
    Inventor: Ram Prakash Sharma
  • Publication number: 20210108847
    Abstract: An ice-machine rotatable assembly and housing, comprising a first side wall defining a first elongate slot extending from an edge of the first side wall, and the rotatable assembly comprising: a rotatable member configured to move liquid toward an ice former mounted with respect to the housing. The rotatable member including a first connecting part towards a first end of the rotatable member; and a first slide plate having a rail and a first side panel extending along a length of the rail of the first slide plate. The rail of the first slide plate being configured to be at least partially received by the first elongate slot, wherein: the first connecting part of the rotatable member is moveable along the elongate slot to position the rotatable member in the installed position. The first slide plate is mountable with its rail at least partially received by the first elongate slot.
    Type: Application
    Filed: February 28, 2018
    Publication date: April 15, 2021
    Inventors: Ram Prakash SHARMA, Vinay SHARMA
  • Publication number: 20200278143
    Abstract: The present disclosure discloses, an evaporator assembly for a vertical flow type ice-making machine. The assembly comprising a plurality of tubes for circulating a refrigerant, and a plurality of conductive protrusions thermally coupled to and extending the plurality of tubes. Each of the plurality of conductive protrusions defines an ice-making region. The assembly also includes a non-conductive plate arranged adjacent to the plurality of tubes. The non-conductive plate is defined with a provision to accommodate the plurality of conductive protrusions which exchanges heat with the refrigerant flowing through the plurality of tubes and forms the ice layer by layer, and shape of at least one surface of the ice is defined by the non-conductive plate. The configuration of the assembly produces ice in the form of individual ice-cubes of a specific shape and size, and thereby improves the efficiency of the machine and ice-making process.
    Type: Application
    Filed: November 27, 2018
    Publication date: September 3, 2020
    Inventors: Ram Prakash SHARMA, Vinay SHARMA
  • Publication number: 20090099307
    Abstract: A process for preparing a peptide by solid phase synthesis in the N to C direction comprising a capping step after an amide bond formation step to prevent or reduce deletion artefacts.
    Type: Application
    Filed: March 13, 2006
    Publication date: April 16, 2009
    Applicant: ACTIVOTEC SPP LIMITED
    Inventor: Ram Prakash Sharma
  • Publication number: 20080242836
    Abstract: A process for preparing a peptide or protein by solid phase synthesis comprising combining a sequence including one or more amino acids obtainable by C-N synthesis linked to a first resin, with an amino acid sequence including one or more amino acid obtainable by N-C synthesis linked to a second resin so as to create a native peptide link between unprotected N and unprotected C terminals of said amino acid sequences, and optionally releasing the resulting peptide from one or more of the linked resins so as to combine with further N-C or C-N sequences or to release the desired peptide or protein sequence.
    Type: Application
    Filed: March 13, 2006
    Publication date: October 2, 2008
    Applicant: UNIVERSITY OF SOUTHAMPTON
    Inventor: Ram Prakash Sharma
  • Patent number: 6620599
    Abstract: The invention provides a process for the production of a biologically active phenolic compound (+) catechin from Taxus wallichiana tissue cultures, said process comprising the steps of (a) inoculating the of explants on a culture medium supplemented with combinations of auxins and cytokinins, (b) incubating the cultures under continuous light or dark conditions for 4-6 weeks for callus initiation followed by subculturing at 4-6 weeks intervals, (c) extracting the fresh pulverized calli with polar solvents at room temperature; (d) evaporating the solvent to obtain a residue; and (e) treating the residue with a chlorinated solvent and isolating (+) catechin compound by filtration.
    Type: Grant
    Filed: March 28, 2000
    Date of Patent: September 16, 2003
    Assignee: Council of Scientific and Industrial Research
    Inventors: Sunil Kumar Chattopadhyay, Suchitra Banerjee, Shipra Agarwal, Manish Kulshrestha, Ram Prakash Sharma, Vijay Kumar Mehta, Sushil Kumar
  • Patent number: 6365757
    Abstract: This invention relates to a process for the production of a compound (+) catechin penta acetate of formula I from Taxus wallichiana tissue cultures which comprises : (a) inoculation of explants on different media compositions supplemented with combinations of auxins (1-5 mg/l) and cytokinins (0.1-1.0 mg/l); (b) incubation of the cultures under continuous light or dark conditions for 4-6 weeks for callus cultures followed by subculturing at 4-6 weeks intervals; (c) harvesting of the calli at different growth phases ranging from 12-36 months; (d) extraction of fresh pulverized calli with polar solvents at room temperature; (e) evaporating the solvent to give a residue; and partitioning of the residue between water and chlorinated solvents and evaporating the solvent to a semisolid mass; (f) subjecting the resultant mass to column chromatography over suitable adsorbent and (g) eluting with organic solvent/mixtures of organic solvents to get (+) catechin penta acetate.
    Type: Grant
    Filed: March 28, 2000
    Date of Patent: April 2, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Sunil Kumar Chattopadhyay, Suchitra Banerjee, Shipra Agarwal, Koneni Venkata Sashidhara, Vinayak Tripathi, Arun Kumar Kukreja, Sushil Kumar, Manish Kulshrestha, Ram Prakash Sharma, Vijay Kumar Mehta
  • Patent number: 6362219
    Abstract: The present invention relates to a synergistic formulation useful for the control of wide spectrum of malarial infections, which comprises a pharmaceutically effective amount of dihydroartemisinin and a vegetable oil.
    Type: Grant
    Filed: November 2, 2000
    Date of Patent: March 26, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Dharam Chand Jain, Rajendra Singh Bhakuni, Ram Prakash Sharma, Sushil Kumar, Guru Prakash Dutta
  • Patent number: 6214864
    Abstract: The present invention relates to a synergistic formulation useful for the control of wide spectrum of malarial infections, which comprises a pharmaceutically effective amount of dihydroartemisinin and a vegetable oil.
    Type: Grant
    Filed: March 5, 1999
    Date of Patent: April 10, 2001
    Assignee: Council of Scientific and Industrial Research
    Inventors: Dharam Chand Jain, Rajendra Singh Bhakuni, Ram Prakash Sharma, Sushil Kumar, Guru Prakash Dutta
  • Patent number: 6184367
    Abstract: The present invention provides a process for the production of two molecules of 4-aryl-2 butanols having the general formula 1 given below: Wherein R═H or glucose from the leaves of Taxus wallichiana, which comprises: (a) defatting air dried, pulverized leaves with aliphatic hydrocarbon solvents, (b) extracting the defatted leaves with chlorinated solvents and polar solvent successively at room temperature, (b) concentrating the chlorinated solvent soluble faction to a residue and treating the residue with aqueous solution of alkali and extracting with chlorinated solvents, (d) acidifying the alkali layer with mineral acid and extracting with ethyl acetate and concentrating the ethyl acetate phase to give compound of formula 1 where R═H, (e) concentrating the polar solvent fraction from step (b) to a residue and treating the residue with aqueous solution of alkali and extracting with chlorinated solvent, and (f) acidifying the alkali phase with mineral acid and extracting wit
    Type: Grant
    Filed: July 21, 1999
    Date of Patent: February 6, 2001
    Assignee: Council of Scientific and Industrial Research
    Inventors: Sunil Kumar Chattopadhyay, Ram Prakash Sharma, Sushil Kumar
  • Patent number: 6127405
    Abstract: The present invention relates to use .alpha.-arteether as a antibacterial agent, preferably for gyr mutant bacteria which are resistant to quinolone drugs and can be used as therapeutic agents for treating drug resistant bacterial infections, and also as a antifungal agent.
    Type: Grant
    Filed: October 27, 1998
    Date of Patent: October 3, 2000
    Assignee: Council of Scientific and Industrial Research
    Inventors: Sushil Kumar, Suman Preet Singh Khanuja, Tiruppadiripuliyur Ranganathan Santha Kumar, Dharam Chand Jain, Suchi Srivastava, Asish Kumar Bhattacharya, Dharmendra Saikia, Ajit Kumar Shasany, Mahendra Pandurang Darokar, Ram Prakash Sharma
  • Patent number: 6028206
    Abstract: The present invention relates to an improved process for the production of important taxol analogues 10-deacetyl taxol A,B and C of the formula (2) ##STR1## R=C.sub.6 H.sub.5 (10 deacetyl taxol A) =CH.sub.3 C.dbd.CHCH.sub.3 (10-deacetyl taxol B)=C.sub.5 H.sub.11 (10-deacetyl taxol C)where R represent C.sub.6 H.sub.5 (10-deacetyl taxol A) or, CH.sub.3 C.dbd.CHCH.sub.3 (10-deacetyl taxol B) or, C.sub.5 H.sub.11 (10-deacetyl taxol C) which comprises (a) dissolving the taxol analogues 7-xylosyl-10-deacetyl taxol A,B,C of the formula (1) ##STR2## R=C.sub.6 H.sub.5 (10 deacetyl taxol A) =CH.sub.3 C.dbd.CHCH.sub.3 (10-deacetyl taxol B)=C.sub.5 H.sub.11 (10-deacetyl taxol C)where R represents C.sub.6 H.sub.5 (taxol analogue A or xyloside A), or CH.sub.3 C.dbd.CHCH.sub.3 (taxol analogue B or xyloside B) or C.sub.5 H.sub.11 (taxol analogue C or xyloside C) in a polar solvent (b) reacting the resultant solution with periodate for 20-40 hours at 20-40.degree. C.
    Type: Grant
    Filed: March 5, 1999
    Date of Patent: February 22, 2000
    Assignee: Council of Scientific and Industrial Research
    Inventors: Sunil Kumar Chattopadhyay, Ram Prakash Sharma, Sushil Kumar
  • Patent number: 5955084
    Abstract: This invention relates to a novel process for the dual production of essential oil and artemisinin from the plant Artemisia annua, said process comprising extracting the plant with hexane, partitioning the hexane extract between hexane and acetonitrile, hydrodistillation of hexane residue and Marc to yield essential oil, further fractionation of acetonitrile solvent between hexane-benzene mixture to remove artemisinic acid, chromatographing of the acetonitrile phase to produce substantially pure artemisinin, the artemisinic acid is reduced to obtain dihydro artemisinic acid which is then oxidised in a single step to form artemisinin.
    Type: Grant
    Filed: October 6, 1997
    Date of Patent: September 21, 1999
    Inventors: Dharam Chand Jain, Sudeep Tandon, Rajendra Singh Bhakuni, Mohammed Shafique Siddique, Atul Prakash Kahol, Ram Prakash Sharma, Sushil Kumar, Asish Kumar Bhattacharya