Patents by Inventor Rama Raju Gokaraju

Rama Raju Gokaraju has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190201470
    Abstract: The invention discloses taste masking formulations for bitter natural compounds, selected from the extracts, fraction and pure phytochemicals produced in combination with a synthetic polymer or a natural polymer. The invention also relates to the novel process of producing the taste masking formulations. The invention also relates to taste masking formulations of Bacopa extracts with no bitter taste or negligible bitter taste in combination with synthetic polymers such as Eudragit or natural polymers such as Shellac.
    Type: Application
    Filed: June 21, 2017
    Publication date: July 4, 2019
    Applicant: Laila Nutraceuticals
    Inventors: Ganga Raju GOKARAJU, Rama Raju GOKARAJU, Kishore Babu GOVADA, Venkata Krishna Raju ALLURI, Nagendra Babu VUTTI, Kiran BHUPATHIRAJU, Venkata Kanaka Ranga Raju GOKARAJU, Trimurtulu GOLAKOTI
  • Publication number: 20190192607
    Abstract: The invention discloses odor masking formulations for stench natural compounds, selected from the extracts, fraction and pure phytochemicals that are produced in combination with a natural or synthetic hydrocolloid polymer gum(s). The invention further discloses novel process of producing the odor and taste masking formulations. The invention also discloses taste masking formulations of valerian extracts with no characteristic stench odor & or negligible stench odor in combination with natural hydrocolloid gum such as guar gum, acacia or other polymers. The invention further discloses method of reducing insomnia, anxiety, Attention Deficit Disorder (ADD), Chronic Fatigue Syndrome (CFS) using odor masking formulation of the current invention. Importantly, the said odor masked formulation of the present disclosure helps in improving sleep cycle and helps in efficient functioning of brain.
    Type: Application
    Filed: September 8, 2017
    Publication date: June 27, 2019
    Inventors: Ganga Raju GOKARAJU, Rama Raju GOKARAJU, Kishore Babu GOVADA, Venkata Krishna Raju ALLURI, Nagendra Babu VUTTI, Kiran BHUPATHIRAJU, Venkata Kanaka Ranga Raju GOKARAJU, Trimurtulu GOLAKOTI
  • Publication number: 20190191752
    Abstract: The invention discloses novel dietary supplements or herbal product comprising at least one ingredient selected from the extracts or fractions derived from Bauhinia racemosa fruit, Cassia auriculata, Mangifera indica stem bark, Woodfordia fruticosa tender stem and Acacia nilotica fruit or their compositions in combination with at least one compound selected from biological actives, herbal extracts, minerals, amino acids, proteins, vitamins, excipient, diluent or carrier as a natural energy enhancer to provide an onset and steady maintenance of energy and for improving muscle strength, muscle mass and mental alertness, for treating sarcopenia and muscular atrophy in a warm blooded animal or mammal in need thereof.
    Type: Application
    Filed: November 20, 2018
    Publication date: June 27, 2019
    Inventors: Ganga Raju GOKARAJU, Trimurtulu GOLAKOTI, Rama Raju GOKARAJU, Kiran BHUPATHIRAJU, Venkata Kanaka Ranga Raju GOKARAJU, Krishanu SENGUPTA, Venkata Krishna Raju ALLURI
  • Publication number: 20190175678
    Abstract: Synergistic nutraceutical or pharmaceutical anti-inflammatory compositions include a therapeutically effective combination of: an extract selectively enriched in 3-O-acetyl-11-keto-?-boswellic acid (AKBA) derived from Boswellia serrata; and a Boswellia serrata non-acidic resin extract (BNRE). The compositions can be used to prevent, control and treat inflammation and several inflammatory related diseases including asthma, osteoarthritis, rheumatoid arthritis, and/or endothelial dysfunction. The invention further discloses the amelioration of pro-inflammatory biomarker proteins or molecules, whose expression/production is altered during inflammatory diseases.
    Type: Application
    Filed: February 19, 2019
    Publication date: June 13, 2019
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Trimurtulu Golakoti, Kiran Bhupathiraju, Venkata Krishna Raju Alluri
  • Patent number: 10286023
    Abstract: The invention relates to a non-acidic Boswellia low polar gum resin extract fraction (BLPRE) in combination with biological agents for enhancing the bioavailability of the biological agents. The invention also provides composition(s) comprising a Boswellia low polar gum resin extract (BLPRE) in combination with a biological agent for increasing the bioavailability of biological agent.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: May 14, 2019
    Assignee: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Trimurtulu Golakoti, Kiran Bhupathiraju, Venkata Krishna Raju Alluri
  • Patent number: 10206964
    Abstract: The present invention discloses synergistic nutraceutical or pharmaceutical or dietary supplement anti-inflammatory compositions comprising therapeutically effective combination of an extract selectively enriched in 3-O-acetyl-1 1-keto-?-boswellic acid (AKBA) derived from Boswellia serrata and Boswellia serrata non-acidic resin extract (BNRE). The composition(s) can be used to prevent, control and treat inflammation and several inflammatory related diseases including asthma, osteoarthritis, rheumatoid arthritis, endothelial dysfunction and the like. The invention further discloses the amelioration of pro-inflammatory biomarker proteins or molecules, whose expression/production is altered during inflammatory diseases.
    Type: Grant
    Filed: June 10, 2015
    Date of Patent: February 19, 2019
    Assignee: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Trimurtulu Golakoti, Kiran Bhupathiraju, Venkata Krishna Raju Alluri
  • Patent number: 10105347
    Abstract: The invention discloses herbal ingredients derived from Sphaeranthus indicus standardized to at least one frullanolide/eudesmanoid sesquiterpene compound and their compositions as natural energy enhancer to provide an onset and steady maintenance of energy and mental alertness in a mammal. The invention further includes the use of ingredients and compositions for food ingredient formulations such as dietary supplement, food ingredient, beverage, snack or energy drink containing the above said herbal ingredient(s) for enhancing physical activity, physical fitness, mental alertness, enhancing energy levels, stamina levels, circulatory health, blood vessel health and for better mental health in warm blooded animal.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: October 23, 2018
    Assignee: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Trimurtulu Golakoti, Kiran Bhupathiraju, Venkata Krishna Raju Alluri
  • Patent number: 10022416
    Abstract: A highly bioavailable, water soluble, sustained release nanoformulation comprising a hydrophobic plant derived compound(s) in an emulsifier phase, and aqueous phase. The formulation provides sustained release of the hydrophobic plant derived compound(s) over a 24 hr time period. A process for preparation of the water soluble nanoformulation is described.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: July 17, 2018
    Assignee: Laila Pharmaceuticals PVT. LTD.
    Inventors: Ravichandran Sripathy, Venkata Narasimha Siva Rama Raju Mandapati, Gopaal Ajay, Nirvanashetty Somashekara, Ramchand Nanappan Chaniyilparampu, Rama Raju Gokaraju, Ganga Raju Gokaraju, Kiran Bhupathiraju, Dwarakanath Anjana
  • Publication number: 20180168655
    Abstract: The present invention discloses novel synergistic dietary supplement compositions comprising at least two ingredients selected from the extracts and fractions derived from Sphaeranthus indicus, Coleus aromaticus, Cissus quadrangularis, Curcuma longa, Garcinia mangostana, Citrullus lanatus, Ocimum sanctum, Trachyspermum ammi and Cinnamomum tamala as natural energy enhancer for enhancing physical performance, muscle strength, muscle mass, mental alertness and energy levels in a mammal.
    Type: Application
    Filed: February 15, 2018
    Publication date: June 21, 2018
    Inventors: Ganga Raju GOKARAJU, Rama Raju GOKARAJU, Venketa Kanaka Ranga Raju GOKARAJU, Kiran BHUPATHIRAJU, Trimurtulu GOLAKATI, Krishanu SENGUPTA, Venkata Krishna Raju ALLURI
  • Patent number: 9907825
    Abstract: The present invention discloses novel synergistic dietary supplement compositions comprising at least two ingredients selected from the extracts and fractions derived from Sphaeranthus indicus, Coleus aromaticus, Cissus quadrangularis, Curcuma longa, Garcinia mangostana, Citrullus lanatus, Ocimum sanctum, Trachyspermum ammi and Cinnamomum tamala as natural energy enhancer for enhancing physical performance, muscle strength, muscle mass, mental alertness and energy levels in a mammal.
    Type: Grant
    Filed: January 2, 2014
    Date of Patent: March 6, 2018
    Assignee: Laila Nutraceuticals
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Kiran Bhupathiraju, Trimurtulu Golakoti, Krishanu Sengupta, Venkata Krishna Raju Alluri
  • Patent number: 9795646
    Abstract: The present disclosure relates to non-acidic extracts or fractions selected from a Boswellia low polar gum resin extract fraction (BLPRE), a Boswellia volatile oil fraction (BVOIL), and a Boswellia oil fraction (BOIL) and their compositions. BLPRE, BOIL, and BVOIL are each derived from the gum resin of a Boswellia species. These compositions are useful for improving mental condition, enhancing brain functions such as cognition, memory, learning, communication and brain health, for treating impaired memory, and for preventing, control or treating memory and cognition related disorders/diseases. Additionally, BOIL, BVOIL, and mixtures of BOIL and BVOIL are useful for enhancing the bioavailability of a biological agent.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: October 24, 2017
    Assignee: Laila Nutraceuticals
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Trimurtulu Golakoti, Kiran Bhupathiraju, Venkata Krishna Raju Alluri
  • Publication number: 20170290875
    Abstract: The present invention relates to synergistic compositions for the treatment of one or more associated conditions of arthritis or rheumatoid arthritis osteoarthritis. More particularly, novel synergistic compositions which comprises a combination of therapeutically effective amounts of: a) an alcoholic/hydroalcoholic extract of Tamarindus indica seed comprising proanthocyanidins either alone or in combination with water extract of Tamarindus indica seed comprising polysaccharides, b) a Curcuma longa rhizome extract comprising curcuminoids, c) optionally containing pharmaceutically or nutraceutically or dietetically acceptable carriers/excipients. The invention also relates to a method of treating one or more associated conditions of arthritis or rheumatoid arthritis or osteoarthritis using synergistic composition.
    Type: Application
    Filed: October 9, 2015
    Publication date: October 12, 2017
    Inventors: Ganga Raju GOKARAJU, Rama Raju GOKARAJU, Venkata Kanaka Ranga Raju GOKARAJU, Trimurtulu GOLAKATI, Kiran BHUPATHIRAJU
  • Patent number: 9504722
    Abstract: The present invention discloses the extracts of Holoptelea integrifolia or the purified fractions isolated there from and the dietary, nutraceutical and pharmaceutical compositions comprising the same or optionally in combination with one or more known anti-obesic agents useful for the purpose of inhibition, amelioration or prevention of adipogenesis and lipolysis involved diseases. The invention further discloses a method for treating or preventing obesity and adipogenesis and lipolysis involved diseases using the compositions containing the extracts of purified fractions of Holoptelea integrifolia.
    Type: Grant
    Filed: August 20, 2007
    Date of Patent: November 29, 2016
    Assignee: Laila Nutraceuticals
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Trimurtulu Golakoti, Krishanu Sengupta, Kiran Bhupatiraju
  • Publication number: 20160339072
    Abstract: An herbal composition, comprising a therapeutically effective amount of an extract of Terminalia chebula; a therapeutically effective amount of an extract of Curcuma longa; and a therapeutically effective amount of a non-acidic, water-immiscible organic solvent extract of a Boswellia serrata resin.
    Type: Application
    Filed: August 5, 2016
    Publication date: November 24, 2016
    Inventors: Ganga Raju GOKARAJU, Rama Raju GOKARAJU, Venkata Kanaka Ranga Raju GOKARAJU, Trimurtulu GOLAKATI, Kiran BHUPATHIRAJU, Venkata Krishna Raju ALLURI, Krishanu SENGUPTA
  • Patent number: 9427425
    Abstract: The current disclosure discloses acetogenin(s), extract(s)/fraction(s) standardized to acetogenin(s) comprising terminal ?,?-unsaturated-?-methyl-?-lactone moiety derived from Annona squamosa or their compositions for prevention, treatment, inhibition or controlling inflammation and immune related diseases or disorders mediated through cytokines/chemokines or other biomarkers. The disclosure further discloses said Annona squamosa derived acetogenin(s), extract(s)/fraction(s) or their compositions for prevention, treatment, inhibition or controlling metabolic diseases/disorders.
    Type: Grant
    Filed: April 18, 2012
    Date of Patent: August 30, 2016
    Assignee: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Trimurtulu Golakoti, Krishanu Sengupta, Kiran Bhupathiraju
  • Patent number: 9345732
    Abstract: The invention discloses phytochemical agents derived from Holoptelea integrifolia and novel composition(s) comprising at least one component selected from the extract(s), fraction(s) and active compound(s) for the protection and alleviation of Metabolic Syndrome, insulin resistance, endothelial dysfunction, chronic kidney disease, atherosclerosis, diabetes and other disease conditions associated with metabolic syndrome. The invention also discloses the amelioration of certain biomarker molecules such as Peroxisome proliferator-activated receptor gamma (PPAR-?), Adipose Differentiation Related Protein (ADRP), CD36, Adipocyte Fatty-acid-Binding Protein (aP2/FABP-4/A-FABP), beta-3 Adrenergic Receptor (?3AR), Leptin, Perilipin and Adiponectin by using the phytochemical components derived from Holoptelea integrifolia.
    Type: Grant
    Filed: November 19, 2009
    Date of Patent: May 24, 2016
    Assignee: Laila Nutraceuticals
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Trimurtulu Golakoti, Kiran Bhupathiraju, Venkateswara Rao Chirravuri, Sivaramakrishna Chillara
  • Patent number: 9301987
    Abstract: Herbal compositions are useful for inhibition, amelioration or prevention of adipogenesis mediated diseases such as obesity, lipid storage disease and hyperlipemia. The herbal compositions comprise biologically effective amounts of extracts or fractions from Piper betle in combination with one or more of the extracts or fractions derived from Dolichos biflorus, Commiphora mukul, Boerhaavia diffusa, Tribulus terrestris and Zingiber officinale as active ingredients. The compositions optionally contain a bio-enhancing agent or a bio-protecting agent, along with biologically acceptable carriers or diluents. The herbal compositions may be used in a method for treating or preventing adipogenesis involved diseases in mammals.
    Type: Grant
    Filed: September 24, 2007
    Date of Patent: April 5, 2016
    Assignee: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Trimurtulu Golakoti, Krishanu Sengupta, Kiran Bhupathiraju, Venkata Krishna Raju Alluri
  • Publication number: 20160074457
    Abstract: Pharmaceutical/dietary supplements and food ingredient(s) derived from Sphaeranthus indicus are used for controlling or treating a metabolic disorder. The supplements and food ingredient(s) are selected from Sphaeranthus indicus extract(s), fraction(s), active compound(s) and phytochemical(s) or mixtures thereof and their compositions, preferably in combination with at least one component selected from the extract(s), fraction(s), active compound(s) and phytochemical(s) or mixtures thereof derived from Garcinia mangostana. The ingredients and the composition(s) can be used for the control, prevention and treatment of obesity, metabolic syndrome, diabetes and other metabolic disorders, and also to regulate energy expenditure, prevention of atherosclerotic plaques in coronary artery and abdominal aorta, increase insulin sensitivity, improve glucose tolerance, lower triglyceride levels and balance glucose levels in mammals.
    Type: Application
    Filed: November 24, 2015
    Publication date: March 17, 2016
    Applicant: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju GOKARAJU, Rama Raju GOKARAJU, Venkata Kanaka Ranga Raju GOKARAJU, Trimurtulu GOLAKOTI, Kiran BHUPATHIRAJU, Krishanu SENGUPTA, Venkata Krishna Raju ALLURI
  • Patent number: 9241964
    Abstract: The invention relates pharmaceutical/dietary supplement/food ingredient(s) selected from the extract(s), fraction(s), active compound(s) and phytochemical(s) or mixtures thereof derived from Sphaeranthus indicus and their compositions, preferably in combination with at least one component selected from the extract(s), fraction(s), active compound(s) and phytochemical(s) or mixtures thereof derived from Garcinia mangostana. The ingredients and the composition(s) can be used for the control, prevention and treatment of obesity, metabolic syndrome, diabetes and other metabolic disorders, and also to regulate energy expenditure, prevention of atherosclerotic plaques in coronary artery and abdominal aorta, increase insulin sensitivity, improve glucose tolerance, lower triglyceride levels and balance glucose levels in mammals.
    Type: Grant
    Filed: February 1, 2010
    Date of Patent: January 26, 2016
    Assignee: LAILA NUTRACEUTICALS
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Venkata Kanaka Ranga Raju Gokaraju, Trimurtulu Golakoti, Kiran Bhupathiraju, Krishanu Sengupta, Venkata Krishna Raju Alluri
  • Publication number: 20160015813
    Abstract: The present invention discloses a composition(s) of hydrophobic plant molecule(s) and/or extract(s) with enhanced bioavailability comprising hydrophobic active and synergetic combination of lecithin and lysolecithin and to the process for preparation thereof.
    Type: Application
    Filed: June 15, 2015
    Publication date: January 21, 2016
    Inventors: Ganga Raju Gokaraju, Rama Raju Gokaraju, Kiran Bhupathiraju, Trimurtulu Golakoti