Patents by Inventor Ramachandra A. Rao

Ramachandra A. Rao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of nateglinide
    Patent number: 8658821
    Abstract: A one-pot process for the preparation of nateglinide, which process comprises reacting an alkyl ester of D-phenylalanine of formula (II): where R represents C1-4alkyl, typically methyl, either as the free base or in salt form (typically the hydrochloride), with trans-4-isopropylcyclohexanecarboxylic acid of formula (III): where X represents hydroxy or halo, typically chloro, to obtain a C1-4 alkyl ester of nateglinide of formula (IV), preferably the methyl ester of nateglinide: followed by hydrolysis to yield nateglinide of formula (I):
    Type: Grant
    Filed: June 8, 2005
    Date of Patent: February 25, 2014
    Assignee: Cipla Limited
    Inventors: Rajendra Narayanrao Kankan, Dharmaraj Ramachandra Rao, Manjinder Singh Phull, Dilip Ramdas Birari
  • POLYNUCLEOTIDE AND POLYPEPTIDE SEQUENCE AND METHODS THEREOF
    Publication number: 20140051842
    Abstract: The present disclosure relates to a field of recombinant DNA therapeutics. It involves the bio-informatics design, synthesis of artificial gene for human insulin precursor including leader peptide coding sequence, cloning in an expression vector and expression in an organism, preferably Pichia pastoris. The present disclosure also relates to methods of downstream processing for obtaining protein precursor molecules and subsequent conversion of precursor molecules to functional proteins.
    Type: Application
    Filed: August 22, 2013
    Publication date: February 20, 2014
    Applicant: BIGTEC PRIVATE LIMITED
    Inventors: Mulakkapurath Narayanan Manoj, Venkata Ramachandra Rao Vasamsetty, Madhuri Baliga, Kirubakaran Naveen Kumar, Chandrasekhar Bhaskaran Nair, Pillarisetti Venkata Subbarao
  • Process for preparation of erlotinib and its pharmaceutically acceptable salts
    Patent number: 8642758
    Abstract: A process for the preparation of a salt of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine comprising reacting a 4-halo-6,7-bis(2-methoxyethoxy) quinazoline with 3-aminophenyl acetylene or an acid salt thereof under acidic conditions to form the corresponding acid salt of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine, the process optionally further comprising converting the acid salt of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine to N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine.
    Type: Grant
    Filed: April 3, 2008
    Date of Patent: February 4, 2014
    Assignee: Cipla Limited
    Inventors: Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan
  • Rifaximin
    Patent number: 8633234
    Abstract: Amorphous rifaximin, methods of making it, and pharmaceutical compositions containing it. Also described are methods of converting amorphous rifaximin to crystalline rifaximin and vice versa.
    Type: Grant
    Filed: September 24, 2007
    Date of Patent: January 21, 2014
    Assignee: Cipla Limited
    Inventors: Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan, Manjinder Singh Phull, Maruti Ghagare
  • SYSTEM AND METHOD FOR GENERATING IMAGE DATA FOR ON-LINE SHOPPING
    Publication number: 20140010449
    Abstract: A method and system for generating image data representative of a person wearing one or more items of clothing includes using computing hardware to process data of one or more images of people wearing items of clothing to extract via segmentation processes data representative of the items of clothing; using computing hardware to process the data representative of the items of clothing to complete one or more missing parts of the data representative of the items of clothing to generate corresponding clothes data; using computing hardware to analyse an image of a target model to determine a pose of the target model in the image; and using computing hardware to metamorphose at least a portion of the clothes data to fit the image of the target model to generate metamorphosed clothes data, and to overlay the metamorphosed clothes data onto the image of the target model.
    Type: Application
    Filed: July 9, 2012
    Publication date: January 9, 2014
    Applicant: STYLEWHILE OY
    Inventors: Jutta Haaramo, Jayasimha Ramachandra Rao, Leonardo Da Silva
  • NOVEL METHOD OF MANUFACTURING WHEEL DISC
    Publication number: 20140007431
    Abstract: In view of the foregoing, an embodiment herein provides a method of manufacturing wheel disc, wherein said method comprising of steps providing a rectangular strip made of metallic materials, circling the strip to form a band, welding the band to form a hoop by welding process, forming one side of the hoop to make the centre portion of the disc, spinning another side of the hoop to form flange of the disc, and achieving varying thickness across the disc to make variable thickness wherever needed, thereby reducing the usage of raw material and reducing wastage and making light weight wheel disc.
    Type: Application
    Filed: February 14, 2012
    Publication date: January 9, 2014
    Applicant: Wheels India Limited
    Inventors: Badrinarayanan Ramachandra Rao, Sundararajan Thiagarajan, Rajaram Balaseshan
  • FEATURE AND DEPLOYMENT RECOMMENDATION SYSTEMS AND METHODS FOR CONTENT MANAGEMENT SYSTEMS TO PROVIDE RECOMMENDATIONS FOR ENHANCED FEATURE USAGE BASED ON USAGE PATTERNS
    Publication number: 20140012797
    Abstract: Feature and deployment recommendation systems and methods for content management systems comprises a vendor-site deployment and one or more customer-site deployments. The vendor-site deployment is configured to recommend an adaptation of any of the one or more customer-site deployments. The vendor-site deployment including a customer configuration repository adapted to store content usage metrics received from one or more customer-site deployments, an analytical engine configured to generate content usage patterns based on the stored content usage metrics, and a recommendation engine configured to recommend the adaptation.
    Type: Application
    Filed: July 5, 2012
    Publication date: January 9, 2014
    Applicant: ORACLE INTERNATIONAL CORPORATION
    Inventors: HARI CHARAN RAMACHANDRA RAO, CHANDRASEKHAR ATLA, GOVINDA RAJ SAMBAMURTHY
  • MODEL FOR GENERATING CUSTOM FILE PLANS TOWARDS MANAGEMENT OF CONTENT AS RECORDS
    Publication number: 20130332429
    Abstract: Convenient approach for managing records with respect to entities based on file plans. In an embodiment, historical data representing policies previously selected is maintained. The historical data is then used to generate custom file plans containing policies most likely to be used by a corresponding user. A list in such custom file plan may have more relevant policies prioritized higher. A user may thus conveniently select a desired policy, and associate the selected policy with a set of entities to cause the selected policies to be applied against management of the set of entities.
    Type: Application
    Filed: June 11, 2012
    Publication date: December 12, 2013
    Applicant: Oracle International Corporation
    Inventors: Bhageerath Arasachetty, Shyam Babu Prasad, Hari Charan Ramachandra Rao
  • CONTENT MANAGEMENT SYSTEM AND METHOD OF MANAGING RETENTION AND DISPOSITION OF CONTENT ITEMS
    Publication number: 20130325822
    Abstract: In specific embodiments, a content management system operable on one or more microprocessors comprises a content repository storing a plurality of content items and a content usage analyzer. The computer is usable to perform one or more operations on one or more contents items stored in the content repository, and when an operation is performed on a content item, audit data is captured related to the operation. The content usage analyzer is configured to identify an idle content item within the content repository based on the captured audit data.
    Type: Application
    Filed: May 30, 2012
    Publication date: December 5, 2013
    Applicant: ORACLE INTERNATIONAL CORPORATION
    Inventors: GOVINDA RAJ SAMBAMURTHY, HARI CHARAN RAMACHANDRA RAO
  • Methods and compositions for the separation of single-walled carbon nanotubes
    Patent number: 8580223
    Abstract: Embodiments herein describe a composition including at least one water-soluble complex having a water-soluble separation agent including a planar portion, at least one pi electron on the planar portion and at least one electron withdrawing group; and a semiconducting single-walled carbon nanotube in an aqueous solution. Further embodiments describe a method of separating metallic single-walled carbon nanotubes and semiconducting single-walled carbon nanotubes including providing carbon nanotubes having an admixture of semiconducting single-walled carbon nanotubes and metallic single-walled carbon nanotubes; and combining the admixture with a water-soluble separation agent in an aqueous solution to form a mixture, in which the water-soluble separation agent includes a planar portion, at least one pi electron on the planar portion and at least one electron withdrawing group.
    Type: Grant
    Filed: July 18, 2012
    Date of Patent: November 12, 2013
    Assignee: Jawaharlal Nehru Centre for Advanced Scientific Research
    Inventors: Chintamani Nagesa Ramachandra Rao, Subi Jacob George, Rakesh Voggu, Kotagiri Venkata Rao
  • Polynucleotide and polypeptide sequence and methods thereof
    Patent number: 8575322
    Abstract: The present disclosure relates to a field of recombinant DNA therapeutics. It involves the bio-informatics design, synthesis of artificial gene for human insulin precursor including leader peptide coding sequence, cloning in an expression vector and expression in an organism, preferably Pichia pastoris. The present disclosure also relates to methods of downstream processing for obtaining protein precursor molecules and subsequent conversion of precursor molecules to functional proteins.
    Type: Grant
    Filed: March 12, 2010
    Date of Patent: November 5, 2013
    Assignee: Bigtec Private Limited
    Inventors: Mulakkapurath Narayanan Manoj, Venkata Ramachandra Rao Vasamsetty, Madhuri Baliga, Kirubakaran Naveen Kumar, Chandrasekhar Bhaskaran Nair, Pillarisetti Venkata Subbarao
  • Process for the preparation of cinacalcet and salts thereof, and intermediates for use in the process
    Patent number: 8575393
    Abstract: There is provided a process for preparing a salt of the (R)- or (S)-isomer of 1-naphthylethylamine with mandelic acid or a derivative thereof, the process comprising reacting racemic 1-naphthylethylamine with mandelic acid or a derivative thereof to obtain the (R)- or (S)-isomer of 1-naphthylethylamine salt (III) with the acid. The salts also form an aspect of the present invention. There is also provided a salt of the (R)- or (S)-isomer of 1-naphthylethylamine with mandelic acid or a derivative thereof. There is also provided a process for preparing cinacalcet (I) or a salt thereof, the process comprising reacting an ester (II) with (R)-1-naphthylethylamine or a salt of (R)-1-naphthylethylamine and mandelic acid or a derivative thereof, to obtain cinacalcet, and optionally converting the cincalcet to a salt thereof.
    Type: Grant
    Filed: March 4, 2010
    Date of Patent: November 5, 2013
    Assignee: CIPLA Limited
    Inventors: Rajendra Narayanrao Kankan, Dharmaraj Ramachandra Rao, Dilip Ramdas Birari
  • SYSTEM, METHOD, AND COMPUTER PROGRAM PRODUCT FOR PERFORMING A REMEDIAL ACTION WITH RESPECT TO A FIRST DEVICE UTILIZING A SECOND DEVICE
    Publication number: 20130247191
    Abstract: A system, method, and computer program product are provided for performing a remedial action with respect to a first device utilizing a second device. In use, data is received from a first device at a second device via a network. Additionally, it is determined whether the data is unwanted, utilizing the second device. Furthermore, a remedial action is performed utilizing the second device at least partially blocking the first device from accessing the network, based on the determination.
    Type: Application
    Filed: May 7, 2009
    Publication date: September 19, 2013
    Inventors: Harish Balasubramanian, Arun Rajaraman, Ravi Honnavalli Ramachandra Rao
  • Crystalline form of tenofovir disoproxil and a process for its preparation
    Patent number: 8519126
    Abstract: Crystalline Form C of tenofovir disoproxil, salts thereof and a process for its preparation. The process involves adding a solution comprising tenofovir disoproxil and an organic solvent to salt-saturated water, whereby the crystalline Form C of tenofovir disoproxil precipitates. The crystalline Form C of tenofovir disoproxil may be converted to a salt thereof. There is also provided a process for purifying a crude product comprising tenofovir monoisoproxil and tenofovir disoproxil.
    Type: Grant
    Filed: July 30, 2008
    Date of Patent: August 27, 2013
    Assignee: Cipla Limited
    Inventors: Manjinder Singh Phull, Rajendra Narayanrao Kankan, Dharmaraj Ramachandra Rao
  • SYSTEMS AND METHODS FOR INTEGRATION OF BUSINESS APPLICATIONS WITH ENTERPRISE CONTENT MANAGEMENT SYSTEMS
    Publication number: 20130219470
    Abstract: Various arrangements for managing access to unstructured data are presented. A plurality of access requests may be received from a plurality of remote computer systems to a plurality of business entities stored by a content management server. In response to receiving a request for access to a business entity of the plurality of business entities stored by a content management server from a remote computer system, an identifier request may be transmitted to the content management server. A response from the content management server may be received in response to the identifier request. A resource locator that comprises the identifier may be created. The resource locator may be transmitted to the remote computer system for use in accessing the business entity.
    Type: Application
    Filed: April 26, 2012
    Publication date: August 22, 2013
    Applicant: Oracle International Corporation
    Inventors: Sreekanth Chintala, Rama Vijjapurapu, Todd Price, Nathan Angstadt, Hari Charan Ramachandra Rao
  • MODEL FOR CAPTURING AUDIT TRAIL DATA WITH REDUCED PROBABILITY OF LOSS OF CRITICAL DATA
    Publication number: 20130198138
    Abstract: An aspect of the present invention provides for capturing of audit trail data related to processing of requests. In an embodiment, the received requests are classified into a first category and a second category. For each request in the first category, the corresponding audit trail data is stored directly into non-volatile storage upon processing of the request. On the other hand, for each request in the second category, the audit trail data is first stored into a volatile memory upon processing of the request, and then later copied from the volatile memory to non-volatile storage. Thus, the audit trail data corresponding to both categories of requests is eventually available stored on non-volatile storage.
    Type: Application
    Filed: January 30, 2012
    Publication date: August 1, 2013
    Applicant: Oracle International Corporation
    Inventors: Govinda Raj SAMBAMURTHY, Hari Charan Ramachandra Rao, Viswanath Pasupuleti
  • Method of synthesis of Bosentan, its polymorphic forms and its salts
    Patent number: 8481730
    Abstract: The present invention relates to alkaline earth metal salts of bosentan, anyhdrous bosentan, polymorphic forms thereof, amorphous bosentan and processes for preparing them. The present invention further relates to a process for the preparation of bosentan and its pharmaceutically acceptable salts.
    Type: Grant
    Filed: January 2, 2009
    Date of Patent: July 9, 2013
    Assignee: CIPLA Limited
    Inventors: Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan, Manjinder Singh Phull, Ashwini Amol Sawant
  • System, method, and computer program product for processing different content each stored in one of a plurality of queues
    Patent number: 8477796
    Abstract: A system, method, and computer program product are provided for processing different content each stored in one of a plurality of queues. In use, a plurality of different content is identified for processing. Additionally, each of the different content is stored in one of a plurality of queues based on a classification thereof. Furthermore, the plurality of different content stored in the plurality of queues is processed.
    Type: Grant
    Filed: February 12, 2008
    Date of Patent: July 2, 2013
    Assignee: McAfee, Inc.
    Inventors: Ravi Honnavalli Ramachandra Rao, Arun Rajaraman, Harish Balasubramanian
  • Process for the Preparation of Nateglinide
    Publication number: 20130165686
    Abstract: The present invention relates to a process for the preparation of substantially pure nateglinide of formula (I), substantially free from the cis-isomer and L-enantiomer and preparation of enantiomerically pure nateglinide form B, directly from the hydrolysis of a (?)-N-(trans-4-isopropylcyclohexyl-1-carbonyl)-D-phenylalanine alkyl ester in a ketonic solvent or water or mixture thereof.
    Type: Application
    Filed: June 14, 2011
    Publication date: June 27, 2013
    Applicant: CIPLA LIMITED
    Inventors: Rajendra Narayanrao Kankan, Dharmaraj Ramachandra Rao, Dilip Ramdas Birari
  • PIEZOELECTRIC DEVICES AND METHODS FOR THEIR PREPARATION AND USE
    Publication number: 20130153924
    Abstract: Methods for fabricating a piezoelectric device are provided. The methods can include providing a substrate and forming a nanocrystalline diamond layer on a first surface of the substrate. The methods can also include depositing a piezoelectric layer on a first surface of the nanocrystalline diamond layer.
    Type: Application
    Filed: December 20, 2011
    Publication date: June 20, 2013
    Applicant: INDIAN INSTITUTE OF TECHNOLOGY MADRAS
    Inventors: Maneesh Chandran, M.S. Ramachandra Rao