Patents by Inventor Ramachandran Chandrasekharan

Ramachandran Chandrasekharan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanoemulsion formulations
    Publication number: 20020155084
    Abstract: The present invention relates to nanoemulsion formulations and methods for delivering biological agents to cells, and in particular nanoemulsion formulations for parenteral and non-parenteral delivery of biological agents to a subject. The nanoemulsion formulations of the present invention may be employed to permit the permeation of biological agents into the skin of subject or to increase the rate of permeation. Biological agents may be delivered by the nanoemulsion formulations of the present invention for diagnostic or therapeutic purposes.
    Type: Application
    Filed: May 30, 2001
    Publication date: October 24, 2002
    Applicant: The Regents of the University of the Michigan
    Inventors: Blake J. Roessler, James R. Baker, Norman D. Weiner, Ramachandran Chandrasekharan, Huai Liang Wu
  • Stimulation of hair follicles
    Patent number: 5834014
    Abstract: A novel method and delivery system for therapeutic weak acid or base materials has been developed. The method and delivery system utilize a therapeutic material which is modified to make it more hydrophilic and encapsulated in a lipid vesicle, preferably a non-phospholipid lipid vesicle. The method and delivery system is particularly well suited to topical delivery of minoxidil.
    Type: Grant
    Filed: October 6, 1995
    Date of Patent: November 10, 1998
    Assignees: The Regents of the University of Michigan, Micro-Pak, Inc.
    Inventors: Norman Weiner, Donald F.H. Wallach, Kamel Egbaria, Ramachandran Chandrasekharan
  • Bioactive composition
    Patent number: 5455286
    Abstract: An improved bioactive agent delivery composition and method of application are described. The composition comprises a bioactive agent, a hydrophilic polymer in an incompletely hydrated state and a substantially water-miscible solvent system. The agent and polymer are essentially dissolved in the solvent system to form a sprayable composition having a viscosity of less than 350 cP. Upon dilution with water, the viscosity of the composition increases to in excess of 1000 cP to produce a retentive coating at the site of application which provides enhanced bioavailability of the agent.
    Type: Grant
    Filed: August 2, 1994
    Date of Patent: October 3, 1995
    Inventors: Gordon L. Amidon, Ramachandran Chandrasekharan, Arthur H. Goldberg
  • Bioactive composition
    Patent number: 5221698
    Abstract: An improved bioactive agent delivery composition and method of application are described. The composition comprises a bioactive agent, a hydrophilic polymer in an incompletely hydrated state and a substantially water-miscible solvent system. The agent and polymer are essentially dissolved in the solvent system to form a sprayable composition having a viscosity of less than 350 cP. Upon dilution with water, the viscosity of the composition increases to in excess of 1,000 cP to produce a retentive coating at the site of application which provides enhanced bioavailability of the agent.
    Type: Grant
    Filed: June 27, 1991
    Date of Patent: June 22, 1993
    Assignee: The Regents of the University of Michigan
    Inventors: Gordon L. Amidon, Ramachandran Chandrasekharan, Arthur H. Goldberg