Patents by Inventor Ramachandran Thekkedath
Ramachandran Thekkedath has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240042181Abstract: The present invention discloses a device for the collection and scavenging of biological samples, and drug delivery for upper and lower respiratory tracts and hollow organs. The device comprises a distal balloon assembly (101) comprising distal carrier disc (101a) and a distal balloon (102), a proximal balloon catheter assembly (103) comprising proximal carrier disc (103a) and a proximal balloon (104), an inflation tube (108), a double lumen catheter (105) with an outer tube (105a) and an inner tube (105b), an agitator (106) working by methods such as ultrasonication, vibration, rotation, to-and-fro movements, pulsations etc, a flexible rod (107) to mount the agitator (106). Thus, the invention provides the device or a catheter with balloons to isolate pathogens or viruses from nasal cavity, nasopharynx, or relevant segment of hollow organs, with or without the use of water or similar liquids.Type: ApplicationFiled: January 11, 2022Publication date: February 8, 2024Inventor: Ramachandran THEKKEDATH
-
Patent number: 11565094Abstract: Disclosed herein are devices for use in transplanting cells. The devices can include a housing defining a cavity; and a support structure separating the cavity into a cell chamber and a reservoir chamber, wherein the support structure comprises a membrane for fluid communication between the cell chamber and reservoir chamber. The cell chamber can define a first opening comprising a microstructure containing an array of micro-channels, each having a diameter to facilitate growth of vascular tissues; and an array of micro-reservoirs, each having a diameter to facilitate housing of cell aggregates individually. The membrane can define a surface area that is at least 50% of a total surface area of the support structure. Methods of treating a subject for a disease condition, such as diabetes, are also disclosed.Type: GrantFiled: October 17, 2018Date of Patent: January 31, 2023Assignee: THE METHODIST HOSPITAL SYSTEMInventors: Marco Farina, Andrea Ballerini, Daniel W. Fraga, Usha Ramachandran Thekkedath, Omaima M. Sabek, Ahmed Osama Gaber, Alessandro Grattoni
-
Publication number: 20210187260Abstract: Disclosed herein are devices for use in transplanting cells. The devices can include a housing defining a cavity; and a support structure separating the cavity into a cell chamber and a reservoir chamber, wherein the support structure comprises a membrane for fluid communication between the cell chamber and reservoir chamber. The cell chamber can define a first opening comprising a microstructure containing an array of micro-channels, each having a diameter to facilitate growth of vascular tissues; and an array of micro-reservoirs, each having a diameter to facilitate housing of cell aggregates individually. The membrane can define a surface area that is at least 50% of a total surface area of the support structure. Methods of treating a subject for a disease condition, such as diabetes, are also disclosed.Type: ApplicationFiled: October 17, 2018Publication date: June 24, 2021Inventors: Marco FARINA, Andrea BALLERINI, Daniel W. FRAGA, Usha Ramachandran THEKKEDATH, Omaima M. SABEK, Ahmed Osama GABER, Alessandro GRATTONI
-
Patent number: 7906338Abstract: A fluid property measurement system for measuring free stream particulates includes a fluid movement device positioned within a fluid container which is configured to cause fluid flow within the fluid container along a fluid flow path when a fluid is present. A constricted region along the fluid flow path generates a region of concentrated streamlined flow within the constricted region and mixing of the fluid outside of the constricted region. A property measuring device is positioned with respect to the constricted region to measure fluid properties in the region of streamlined flow.Type: GrantFiled: June 18, 2008Date of Patent: March 15, 2011Assignee: Thrombodyne, Inc.Inventors: Sivaprasad Sukavaneshvar, Johnny Rhodes, Ramachandran Thekkedath
-
Publication number: 20090162885Abstract: A fluid property measurement system for measuring free stream particulates comprises a fluid movement device positioned within a fluid container which is configured to cause fluid flow within the fluid container along a fluid flow path when a fluid is present. A constricted region along the fluid flow path generates a region of concentrated streamlined flow within the constricted region and mixing of the fluid outside of the constricted region. A property measuring device is positioned with respect to the constricted region to measure fluid properties in the region of streamlined flow.Type: ApplicationFiled: June 18, 2008Publication date: June 25, 2009Inventors: Sivaprasad Sukavaneshvar, Johnny Rhodes, Ramachandran Thekkedath
-
Patent number: 7393690Abstract: A method for measuring properties of a fluid including placing a quantity of fluid in a container; inducing flow in the fluid wherein the flow is substantially streamlined in at least a measuring region of the container by constricting flow, and wherein the fluid is recirculated through the measuring region. A mixing region can be created separate from the measuring region sufficient to substantially mix the fluid. Free stream particulates in the fluid can be measured in the streamlined region. The invention is of particular interest in the assessment of blood platelet function. The method provides specific localized regions of thorough mixing that enable reproducible platelet aggregation, and also provides specific localized regions of streamlined flow that enable certain modalities of assessing aggregation. Both of these regions of flow are induced such that damage to platelet aggregates and other blood components as well as undesirable agglomeration on device surfaces is minimized.Type: GrantFiled: August 15, 2006Date of Patent: July 1, 2008Assignee: Thrombodyne, Inc.Inventors: Sivaprasad Sukavaneshvar, Johnny Rhodes, Ramachandran Thekkedath
-
Patent number: 7262059Abstract: A method for measuring properties of a fluid including placing a quantity of fluid in a container; inducing flow in the fluid wherein the flow is substantially streamlined in at least a measuring region of the container, and wherein the fluid is recirculated through the measuring region; creating a mixing region separate from the measuring region sufficient to substantially mix the fluid; and measuring a property of the fluid in the streamlined region. The invention is of particular interest in the assessment of blood platelet function. The method provides specific localized regions of thorough mixing that enable reproducible platelet aggregation, and also provides specific localized regions of streamlined flow that enable certain modalities of assessing aggregation. Both of these regions of flow are induced such that damage to platelet aggregates and other blood components is minimized.Type: GrantFiled: May 6, 2003Date of Patent: August 28, 2007Assignee: Thrombodyne, Inc.Inventors: Yu Zheng, Sivaprasad Sukavaneshvar, Ramachandran Thekkedath
-
Publication number: 20070041874Abstract: A method for measuring properties of a fluid including placing a quantity of fluid in a container; inducing flow in the fluid wherein the flow is substantially streamlined in at least a measuring region of the container by constricting flow, and wherein the fluid is recirculated through the measuring region. A mixing region can be created separate from the measuring region sufficient to substantially mix the fluid. Free stream particulates in the fluid can be measured in the streamlined region. The invention is of particular interest in the assessment of blood platelet function. The method provides specific localized regions of thorough mixing that enable reproducible platelet aggregation, and also provides specific localized regions of streamlined flow that enable certain modalities of assessing aggregation. Both of these regions of flow are induced such that damage to platelet aggregates and other blood components as well as undesirable agglomeration on device surfaces is minimized.Type: ApplicationFiled: August 15, 2006Publication date: February 22, 2007Inventors: Sivaprasad Sukavaneshvar, Johnny Rhodes, Ramachandran Thekkedath
-
Publication number: 20040224419Abstract: A method for measuring properties of a fluid including placing a quantity of fluid in a container; inducing flow in the fluid wherein the flow is substantially streamlined in at least a measuring region of the container, and wherein the fluid is recirculated through the measuring region; creating a mixing region separate from the measuring region sufficient to substantially mix the fluid; and measuring a property of the fluid in the streamlined region. The invention is of particular interest in the assessment of blood platelet function. The method provides specific localized regions of thorough mixing that enable reproducible platelet aggregation, and also provides specific localized regions of streamlined flow that enable certain modalities of assessing aggregation. Both of these regions of flow are induced such that damage to platelet aggregates and other blood components is minimized.Type: ApplicationFiled: May 6, 2003Publication date: November 11, 2004Applicant: Thrombodyne, Inc.Inventors: Yu Zheng, Sivaprasad Sukavaneshvar, Ramachandran Thekkedath