Patents by Inventor Ramakrishnan Vishwanath

Ramakrishnan Vishwanath has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230303970
    Abstract: The invention encompasses methods for reducing the proportion of sperm cells with abnormal morphology, and unviable sperm cells, in a sperm cell population.
    Type: Application
    Filed: April 13, 2023
    Publication date: September 28, 2023
    Applicant: Inguran, LLC
    Inventors: Juan Moreno, Kenneth Michael Evans, Ramakrishnan Vishwanath, Clara Gonzalez-Marin
  • Patent number: 11629330
    Abstract: The invention encompasses methods for reducing the proportion of sperm cells with abnormal morphology, and unviable sperm cells, in a sperm cell population.
    Type: Grant
    Filed: March 18, 2020
    Date of Patent: April 18, 2023
    Assignee: Inguran, LLC
    Inventors: Juan Moreno, Kenneth Michael Evans, Ramakrishnan Vishwanath, Clara Gonzalez-Marin
  • Publication number: 20230097054
    Abstract: The present invention relates to compositions comprising low sugar media, the methods of using these compositions to reduce trauma and stress on processed animal sperm, the resulting sperm and embryo products, and the methods of use of these products to increase the quality, quantity and viability of progeny and improved rates of births in animals.
    Type: Application
    Filed: April 15, 2022
    Publication date: March 30, 2023
    Applicant: Inguran, LLC
    Inventors: Thomas B. Gilligan, Ramakrishnan Vishwanath, Kilby Willenburg
  • Patent number: 11448653
    Abstract: Cell sorting methods that improve sorting efficiency and productivity by elevating sorting pressures and incorporate certain steps to help the cells better survive such elevated pressures. In the case of sperm, sorting the steps of standardizing sperm samples, staining sperm samples in a single step, calibrating a flow cytometer to place sperm in the leading edge of droplets, and changing a catch fluid distance may be incorporated individually, or in combination to help sperm better survive the sex sorting process.
    Type: Grant
    Filed: March 2, 2020
    Date of Patent: September 20, 2022
    Assignee: Inguran, LLC
    Inventors: Kenneth Michael Evans, Thomas Boyd Gilligan, Richard W. Lenz, Ramakrishnan Vishwanath, Clara Gonzalez-Marin
  • Publication number: 20220186182
    Abstract: Embodiments of the present invention relate generally to processes, systems, and compositions useful in manipulating a ratio of viable X chromosome bearing sperm to viable Y chromosome bearing sperm in at least one sperm population and useful for preserving the resulting manipulated sperm population. In some embodiments a cryoprotectant may be incorporated into various medias used in manipulating the sperm sample, such as in a staining media, a sheath fluid, and a collection media.
    Type: Application
    Filed: February 7, 2022
    Publication date: June 16, 2022
    Applicant: Inguran, LLC
    Inventors: Thomas B. Gilligan, Clara Gonzalez-Marin, Ramakrishnan Vishwanath
  • Patent number: 11326146
    Abstract: The present invention relates to compositions comprising low sugar media, the methods of using these compositions to reduce trauma and stress on processed animal sperm, the resulting sperm and embryo products, and the methods of use of these products to increase the quality, quantity and viability of progeny and improved rates of births in animals.
    Type: Grant
    Filed: November 20, 2015
    Date of Patent: May 10, 2022
    Assignee: Inguran, LLC
    Inventors: Thomas B. Gilligan, Ramakrishnan Vishwanath, Kilby Willenburg
  • Patent number: 11279913
    Abstract: Embodiments of the present invention relate generally to processes, systems, and compositions useful in manipulating a ratio of viable X chromosome bearing sperm to viable Y chromosome bearing sperm in at least one sperm population and useful for preserving the resulting manipulated sperm population. In some embodiments a cryoprotectant may be incorporated into various medias used in manipulating the sperm sample, such as in a staining media, a sheath fluid, and a collection media.
    Type: Grant
    Filed: January 19, 2018
    Date of Patent: March 22, 2022
    Assignee: Inguran, LLC
    Inventors: Thomas B. Gilligan, Clara Gonzalez-Marin, Ramakrishnan Vishwanath
  • Patent number: 10932451
    Abstract: Exemplary embodiments are directed to sensor apparatuses for attachment to an animal that include a housing and a sensor assembly. The housing can be attachable to the animal and includes an internal cavity formed therein. The sensor assembly can be disposed within the internal cavity of the housing. The sensor assembly includes a force sensor and an accelerometer arranged to detect force data and accelerometer data representative of a physiological state of the animal. Exemplary embodiments are also directed to method and sensor systems for detecting a physiological state of an animal.
    Type: Grant
    Filed: December 23, 2019
    Date of Patent: March 2, 2021
    Assignee: ST Reproductive Technologies, LLC
    Inventors: Johnathan Charles Sharpe, Philip Rowe, Ramakrishnan Vishwanath, Paul Julian Martinsen
  • Publication number: 20200299640
    Abstract: The invention encompasses methods for reducing the proportion of sperm cells with abnormal morphology, and unviable sperm cells, in a sperm cell population.
    Type: Application
    Filed: March 18, 2020
    Publication date: September 24, 2020
    Applicant: Inguran, LLC
    Inventors: Juan Moreno, Kenneth Michael Evans, Ramakrishnan Vishwanath, Clara Gonzalez-Marin
  • Publication number: 20200200762
    Abstract: Cell sorting methods that improve sorting efficiency and productivity by elevating sorting pressures and incorporate certain steps to help the cells better survive such elevated pressures. In the case of sperm, sorting the steps of standardizing sperm samples, staining sperm samples in a single step, calibrating a flow cytometer to place sperm in the leading edge of droplets, and changing a catch fluid distance may be incorporated individually, or in combination to help sperm better survive the sex sorting process.
    Type: Application
    Filed: March 2, 2020
    Publication date: June 25, 2020
    Applicant: Inguran, LLC
    Inventors: Kenneth Michael Evans, Thomas Boyd Gilligan, Richard W. Lenz, Ramakrishnan Vishwanath, Clara Gonzalez-Marin
  • Publication number: 20200128795
    Abstract: Exemplary embodiments are directed to sensor apparatuses for attachment to an animal that include a housing and a sensor assembly. The housing can be attachable to the animal and includes an internal cavity formed therein. The sensor assembly can be disposed within the internal cavity of the housing. The sensor assembly includes a force sensor and an accelerometer arranged to detect force data and accelerometer data representative of a physiological state of the animal. Exemplary embodiments are also directed to method and sensor systems for detecting a physiological state of an animal.
    Type: Application
    Filed: December 23, 2019
    Publication date: April 30, 2020
    Applicant: ST Reproductive Technologies, LLC
    Inventors: Johnathan Charles Sharpe, Philip Rowe, Ramakrishnan Vishwanath, Paul Julian Martinsen
  • Patent number: 10620213
    Abstract: Cell sorting methods that improve sorting efficiency and productivity by elevating sorting pressures and incorporate certain steps to help the cells better survive such elevated pressures. In the case of sperm, sorting the steps of standardizing sperm samples, staining sperm samples in a single step, calibrating a flow cytometer to place sperm in the leading edge of droplets, and changing a catch fluid distance may be incorporated individually, or in combination to help sperm better survive the sex sorting process.
    Type: Grant
    Filed: October 3, 2013
    Date of Patent: April 14, 2020
    Assignee: Inguran, LLC
    Inventors: Kenneth Michael Evans, Thomas Boyd Gilligan, Richard W. Lenz, Ramakrishnan Vishwanath, Clara Gonzalez-Marin
  • Patent number: 10563170
    Abstract: The present invention generally relates to compositions and methods for the handling of processed sperm populations including samples that are freshly collected, those transported as fresh samples, as well as samples that are frozen and thawed, those sorted into one or more subpopulations, and those that are otherwise processed or handled that impose trauma on the sperm cell. Such trauma can reduce the motility, fertility, viability and overall integrity of the sperm and reduce the sperm's ability to fertilize an egg, grow into a health embryo and produce a healthy offspring.
    Type: Grant
    Filed: April 17, 2018
    Date of Patent: February 18, 2020
    Assignee: Inguran, LLC
    Inventors: Richard Lenz, Juan Moreno, Ramakrishnan Vishwanath
  • Patent number: 10555504
    Abstract: Exemplary embodiments are directed to sensor apparatuses for attachment to an animal that include a housing and a sensor assembly. The housing can be attachable to the animal and includes an internal cavity formed therein. The sensor assembly can be disposed within the internal cavity of the housing. The sensor assembly includes a force sensor and an accelerometer arranged to detect force data and accelerometer data representative of a physiological state of the animal. Exemplary embodiments are also directed to method and sensor systems for detecting a physiological state of an animal.
    Type: Grant
    Filed: July 10, 2019
    Date of Patent: February 11, 2020
    Assignee: ST Reproductive Technologies, LLC
    Inventors: Johnathan Charles Sharpe, Philip Rowe, Ramakrishnan Vishwanath, Paul Julian Martinsen
  • Publication number: 20190327939
    Abstract: Exemplary embodiments are directed to sensor apparatuses for attachment to an animal that include a housing and a sensor assembly. The housing can be attachable to the animal and includes an internal cavity formed therein. The sensor assembly can be disposed within the internal cavity of the housing. The sensor assembly includes a force sensor and an accelerometer arranged to detect force data and accelerometer data representative of a physiological state of the animal. Exemplary embodiments are also directed to method and sensor systems for detecting a physiological state of an animal.
    Type: Application
    Filed: July 10, 2019
    Publication date: October 31, 2019
    Applicant: ST Reproductive Technologies, LLC
    Inventors: Johnathan Charles Sharpe, Philip Rowe, Ramakrishnan Vishwanath, Paul Julian Martinsen
  • Patent number: 10400213
    Abstract: This disclosure relates to cell sorting methods, and particularly cell sorting methods that improve the efficiency or productivity of sorting in a particle sorting instrument utilizing a measured parameter of sorting efficiency. In one embodiment, minimum productivity and minimum purity may be established and maintained while attempting to maximize the sorting efficiency. While in another embodiment, a minimum sorting efficiency and a minimum purity may be established and maintained while attempting to maximize the productivity of a sort.
    Type: Grant
    Filed: March 4, 2013
    Date of Patent: September 3, 2019
    Assignee: Inguran, LLC
    Inventors: Kenneth Michael Evans, Thomas Boyd Gilligan, Johnathan Charles Sharpe, Juan Moreno, Ramakrishnan Vishwanath
  • Patent number: 10349632
    Abstract: Exemplary embodiments are directed to sensor apparatuses for attachment to an animal that include a housing and a sensor assembly. The housing can be attachable to the animal and includes an internal cavity formed therein. The sensor assembly can be disposed within the internal cavity of the housing. The sensor assembly includes a force sensor and an accelerometer arranged to detect force data and accelerometer data representative of a physiological state of the animal. Exemplary embodiments are also directed to method and sensor systems for detecting a physiological state of an animal.
    Type: Grant
    Filed: August 7, 2017
    Date of Patent: July 16, 2019
    Assignee: ST Reproductive Technologies, LLC
    Inventors: Johnathan Charles Sharpe, Philip Rowe, Ramakrishnan Vishwanath, Paul Julian Martinsen
  • Patent number: 10226041
    Abstract: The present invention generally relates to compositions and methods for the handling of processed sperm populations including samples that are freshly collected, those transported as fresh samples, as well as samples that are frozen and thawed, those sorted into one or more subpopulations, and those that are otherwise processed or handled that impose trauma on the sperm cell. Such trauma can reduce the motility, fertility, viability and overall integrity of the sperm and reduce the sperm's ability to fertilize an egg, grow into a health embryo and produce a healthy offspring.
    Type: Grant
    Filed: August 17, 2017
    Date of Patent: March 12, 2019
    Assignee: Inguran, LLC
    Inventors: Richard Lenz, Juan Moreno, Ramakrishnan Vishwanath
  • Patent number: 10080348
    Abstract: Exemplary embodiments are directed to sensor apparatuses for attachment to an animal that include a housing and a sensor assembly. The housing can be attachable to the animal and includes an internal cavity formed therein. The sensor assembly can be disposed within the internal cavity of the housing. The sensor assembly includes a force sensor and an accelerometer arranged to detect force data and accelerometer data representative of a physiological state of the animal. Exemplary embodiments are also directed to method and sensor systems for detecting a physiological state of an animal.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: September 25, 2018
    Assignee: ST Reproductive Technologies, LLC
    Inventors: Johnathan Charles Sharpe, Philip Rowe, Ramakrishnan Vishwanath, Paul Julian Martinsen
  • Publication number: 20180237747
    Abstract: The present invention generally relates to compositions and methods for the handling of processed sperm populations including samples that are freshly collected, those transported as fresh samples, as well as samples that are frozen and thawed, those sorted into one or more subpopulations, and those that are otherwise processed or handled that impose trauma on the sperm cell. Such trauma can reduce the motility, fertility, viability and overall integrity of the sperm and reduce the sperm's ability to fertilize an egg, grow into a health embryo and produce a healthy offspring.
    Type: Application
    Filed: April 17, 2018
    Publication date: August 23, 2018
    Applicant: Inguran, LLC
    Inventors: Richard Lenz, Juan Moreno, Ramakrishnan Vishwanath