Patents by Inventor Ramakrisna Mukkamala

Ramakrisna Mukkamala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and methods for model-based estimation of cardiac ejection fraction, cardiac contractility, and ventricular end-diastolic volume
    Patent number: 8235910
    Abstract: The methods and systems for estimating cardiac ejection fraction, cardiac contractility, and ventricular end-diastolic volume on a beat-by-beat basis include observing arterial blood pressure waveforms to determine ventricular compliances for a pressure-volume loop in the ventricle. Uncalibrated or calibrated cardiac ejection fraction may be calculated from estimates of stroke volume and the ventricular compliances. Cardiac contractility may be calculated from estimates of a ventricular compliance. Uncalibrated or calibrated ventricular end-diastolic volume may also be calculated from estimates of stroke volume and the ventricular compliances. A set of calibration parameters for calibrating cardiac ejection fraction or ventricular end-diastolic volume may be estimated in a least-squares manner.
    Type: Grant
    Filed: May 16, 2008
    Date of Patent: August 7, 2012
    Inventors: Tushar A. Parlikar, George C. Verghese, Thomas Heldt, Ramakrisna Mukkamala
  • SYSTEMS AND METHODS FOR MODEL-BASED ESTIMATION OF CARDIAC EJECTION FRACTION, CARDIAC CONTRACTILITY, AND VENTRICULAR END-DIASTOLIC VOLUME
    Publication number: 20080294057
    Abstract: The methods and systems for estimating cardiac ejection fraction, cardiac contractility, and ventricular end-diastolic volume on a beat-by-beat basis include observing arterial blood pressure waveforms to determine ventricular compliances for a pressure-volume loop in the ventricle. Uncalibrated or calibrated cardiac ejection fraction may be calculated from estimates of stroke volume and the ventricular compliances. Cardiac contractility may be calculated from estimates of a ventricular compliance. Uncalibrated or calibrated ventricular end-diastolic volume may also be calculated from estimates of stroke volume and the ventricular compliances. A set of calibration parameters for calibrating cardiac ejection fraction or ventricular end-diastolic volume may be estimated in a least-squares manner.
    Type: Application
    Filed: May 16, 2008
    Publication date: November 27, 2008
    Inventors: Tushar A. Parlikar, George C. Verghese, Thomas Heldt, Ramakrisna Mukkamala