Patents by Inventor Ramamoorthy Kottamalai

Ramamoorthy Kottamalai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclic amide derivatives as inhibitors of 11-?-hydroxysteroid dehydrogenase and uses thereof
    Patent number: 9453014
    Abstract: The present invention relates amide compounds of formula (I): wherein R1, R1a, Ar, A, B, W1, W2, D, a, b, and c are defined herein, and pharmaceutical acceptable salts thereof. These compounds have the ability to inhibit 11-?-hydroxysteroid dehydrogenase type 1 (11?-HSD-1) and which are therefore useful in the treatment of certain disorders that can be prevented or treated by inhibition of this enzyme. In addition the invention relates to the compounds, methods for their preparation, pharmaceutical compositions containing the compounds and the uses of these compounds in the treatment of certain disorders. It is expected that the compounds of the invention will find application in the treatment of conditions such as non-insulin dependent type 2 diabetes mellitus (NIDDM), insulin resistance, obesity, impaired fasting glucose, impaired glucose tolerance, lipid disorders such as dyslipidemia, hypertension and as well as other diseases and conditions.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: September 27, 2016
    Assignee: Connexios Life Sciences Pvt. Ltd.
    Inventors: Jagannath Madanahalli Ranganath Rao, Uppala Venkatesham, Jenson George, George Fernand, Sivanageswara Rao Doppalapudi, G R Madhavan, Nagarajan Arumugam, Mohammed Ansari, K Murugavel, Jidugu Pradeep, Sulthan Allavuddeen, K Vijayaramalingam, Hampelingaiah Shiva Prasad, Augustine Michael Raj, S Gnanavel, Ramamoorthy Kottamalai, Naresh M P S Babu, Bommegowda Yadaganahalli Kenchegowda
  • Agonists of GPR40
    Patent number: 9278915
    Abstract: The present invention relates to compounds that have the ability to modulate the activity of GPR40 and are therefore useful in the treatment of GPR40 related disorders. In addition the invention relates to the compounds, methods for their preparation, pharmaceutical compositions containing the compounds and the uses of these compounds in the treatment of certain disorders related to GPR40 activity.
    Type: Grant
    Filed: July 20, 2011
    Date of Patent: March 8, 2016
    Assignee: CONNEXIOS LIFE SCIENCES PVT LTD
    Inventors: Jagannath Madanahalli Ranganath Rao, Nagarajan Arumugam, Mohd Mudabbir Ansari, Chandrasekhar Gudla, Shanmugam Pachiyappan, Manivannan Ramalingam, Jenson George, George Fernanda Arul, Kenchegowda Bommegowda, Y, Sathesh Kumar Angupillai, Ramamoorthy Kottamalai, Pradeep Jidugu, Shivanageshwara Rao, D
  • CYCLIC AMIDE DERIVATIVES AS INHIBITORS OF 11 - BETA - HYDROXYSTEROID DEHYDROGENASE AND USES THEREOF
    Publication number: 20150158860
    Abstract: The present invention relates to certain amide derivatives that have the ability to inhibit 11-?-hydroxysteroid dehydrogenase type 1 (11?-HSD-1) and which are therefore useful in the treatment of certain disorders that can be prevented or treated by inhibition of this enzyme. In addition the invention relates to the compounds, methods for their preparation, pharmaceutical compositions containing the compounds and the uses of these compounds in the treatment of certain disorders. It is expected that the compounds of the invention will find application in the treatment of conditions such as non-insulin dependent type 2 diabetes mellitus (NIDDM), insulin resistance, obesity, impaired fasting glucose, impaired glucose tolerance, lipid disorders such as dyslipidemia, hypertension and as well as other diseases and conditions.
    Type: Application
    Filed: December 21, 2012
    Publication date: June 11, 2015
    Inventors: Jagannath Madanahalli Ranganath Rao, Uppala Venkatesham, Jenson George, George Fernand, Sivanageswara Rao Doppalapudi, G R Madhavan, Nagarajan Arumugam, Mohammed Ansari, K. Murugavel, Jidugu Pradeep, Sulthan Allavuddeen, K. Vijayaramalingam, Hampelingaiah Shiva Prasad, Augustine Michael Raj, S. Gnanavel, Ramamoorthy Kottamalai, Naresh M P S Babu, Bommegowda Yadaganahalli Kenchegowda
  • AGONISTS OF GPR40
    Publication number: 20130237571
    Abstract: The present invention relates to compounds that have the ability to modulate the activity of GPR40 and are therefore useful in the treatment of GPR40 related disorders. In addition the invention relates to the compounds, methods for their preparation, pharmaceutical compositions containing the compounds and the uses of these compounds in the treatment of certain disorders related to GPR40 activity.
    Type: Application
    Filed: July 20, 2011
    Publication date: September 12, 2013
    Applicant: Conexios Life Sciences PVT. LTD.
    Inventors: Jagannath Madanahalli Ranganath Rao, Nagarajan Arumugam, Mohd Mudabbir Ansari, Chandrasekhas Gudla, Shanmugam Pachiyappan, Manivannan Ramalingam, Jenson George, George Fernanda Arul, Kenchegowda Bommegowda, Y, Sathesh Kumar Angupillai, Ramamoorthy Kottamalai, Pradeep Jidugu, Shivanageshwara Rao, D