Patents by Inventor Ramasamy M. Mannan

Ramasamy M. Mannan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microfluidized oil-in-water emulsions and vaccine compositions
    Patent number: 8771727
    Abstract: This invention provides submicron oil-in-water emulsions useful as a vaccine adjuvant for enhancing the immunogenicity of antigens. The present invention also provides vaccine compositions containing an antigen combined with such emulsions intrinsically or extrinsically. Methods of preparing the emulsions and vaccines are also provided by the present invention.
    Type: Grant
    Filed: December 31, 2009
    Date of Patent: July 8, 2014
    Assignee: Zoetis LLC
    Inventors: Paul J. Dominowski, Ramasamy M. Mannan, Richard L. Krebs, Pamela K. Klose
  • Adjuvant compositions
    Patent number: 8580280
    Abstract: This invention relates to adjuvant formulations comprising various combinations of triterpenoids, sterols, immunomodulators, polymers, and Th2 stimulators; methods for making the adjuvant compositions; and the use of the adjuvant formulations in immunogenic and vaccine compositions with different antigens. This invention further relates to the use of the formulations in the treatment of animals.
    Type: Grant
    Filed: June 24, 2009
    Date of Patent: November 12, 2013
    Assignee: Zoetis LLC
    Inventors: Paul J. Dominowski, Ramasamy M. Mannan, Richard L. Krebs, James R. Thompson, Tedd A. Childers, Mary K. Olsen, Robert J. Yancey, Jr., Risini Weeratna, Shucheng Zhang, Cedo M. Bagi
  • Heat treated bacterins, and emulsion vaccines prepared from such heat treated bacterins
    Patent number: 8491915
    Abstract: Heat treated bacterins, a method of producing heat treated bacterins, and emulsion vaccines prepared from such heat treated bacterins are disclosed.
    Type: Grant
    Filed: September 7, 2007
    Date of Patent: July 23, 2013
    Assignee: AH USA 42 LLC
    Inventors: Mark D. Goodyear, Michael J. Huether, Ramasamy M. Mannan, Nancee L. Oien
  • Glycolipid adjuvant compositions
    Patent number: 8460679
    Abstract: This invention relates to compositions and methods of preparing stable adjuvant diluent stock solutions and final adjuvant solutions comprising glycolipids, weak acids, alcohols, nonionic surfactants and buffers.
    Type: Grant
    Filed: January 26, 2007
    Date of Patent: June 11, 2013
    Assignee: Zoetis LLC
    Inventors: Ramasamy M. Mannan, Paul J. Dominowski, Sangita Mediratta
  • NOVEL ADJUVANT COMPOSITIONS
    Publication number: 20090324641
    Abstract: This invention relates to adjuvant formulations comprising various combinations of triterpenoids, sterols, immunomodulators, polymers, and Th2 stimulators; methods for making the adjuvant compositions; and the use of the adjuvant formulations in immunogenic and vaccine compositions with different antigens. This invention further relates to the use of the formulations in the treatment of animals.
    Type: Application
    Filed: June 24, 2009
    Publication date: December 31, 2009
    Applicant: PFIZER INC.
    Inventors: Paul J. Dominowski, Ramasamy M. Mannan, Richard L. Krebs, James R. Thompson, Tedd A. Childers, Mary K. Olsen, Robert J. Yancey, Jr., Risini Weeratna, Shucheng Zhang, Cedo M. Bagi
  • HEAT TREATED BACTERINS, AND EMULSION VACCINES PREPARED FROM SUCH HEAT TREATED BACTERINS
    Publication number: 20080112970
    Abstract: Heat treated bacterins, a method of producing heat treated bacterins, and emulsion vaccines prepared from such heat treated bacterins are disclosed.
    Type: Application
    Filed: September 7, 2007
    Publication date: May 15, 2008
    Applicant: Pfizer Inc.
    Inventors: Mark D. Goodyear, Michael J. Huether, Ramasamy M. Mannan, Nancee L. Oien
  • Microfluidized oil-in-water emulsions and vaccine compositions
    Patent number: 7122191
    Abstract: This invention provides submicron oil-in-water emulsions useful as a vaccine adjuvant for enhancing the immunogenicity of antigens. The present invention also provides vaccine compositions containing an antigen combined with such emulsions intrinsically or extrinsically. Methods of preparing the emulsions and vaccines are also provided by the present invention.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: October 17, 2006
    Assignee: Pfizer Inc.
    Inventors: Paul Joseph Dominowski, Pamela K. Klose, Richard L. Krebs, Ramasamy M. Mannan