Patents by Inventor Ramasamy Sakthivel

Ramasamy Sakthivel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CELLULAR BONE GRAFTS, AND METHODS OF MANUFACTURE AND USE
    Publication number: 20230074239
    Abstract: The disclosure provides bone graft materials, methods for their use and manufacture. Exemplary bone graft materials comprise combining a radiopaque component with a cancellous bone component to produce a bone graft material, wherein the cancellous bone component comprises native osteoreparative cells. Methods for treating a subject with the bone graft material are also provided.
    Type: Application
    Filed: August 15, 2022
    Publication date: March 9, 2023
    Applicant: AlloSource
    Inventors: Reginald STILWELL, Ramasamy SAKTHIVEL, William MASLANIK
  • Cellular bone grafts, and methods of manufacture and use
    Patent number: 11452796
    Abstract: The disclosure provides bone graft materials, methods for their use and manufacture. Exemplary bone graft materials comprise combining a radiopaque component with a cancellous bone component to produce a bone graft material, wherein the cancellous bone component comprises native osteoreparative cells. Methods for treating a subject with the bone graft material are also provided.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: September 27, 2022
    Assignee: AlloSource
    Inventors: Reginald Stilwell, Ramasamy Sakthivel, William Maslanik
  • CELLULAR BONE GRAFTS, AND METHODS OF MANUFACTURE AND USE
    Publication number: 20210146007
    Abstract: The disclosure provides bone graft materials, methods for their use and manufacture. Exemplary bone graft materials comprise combining a radiopaque component with a cancellous bone component to produce a bone graft material, wherein the cancellous bone component comprises native osteoreparative cells. Methods for treating a subject with the bone graft material are also provided.
    Type: Application
    Filed: June 29, 2018
    Publication date: May 20, 2021
    Applicant: AlloSource
    Inventors: Ramasamy SAKTHIVEL, Reginald STILWELL, William MASLANIK
  • Erythrocytes differentiated in vitro from nanofiber expanded CD133+ cells
    Patent number: 8669106
    Abstract: The invention provides, among other things, methods and systems for expanding CD133+ cells. The invention further provides methods and systems for increasing the blood flow to an ischemic tissue in a subject in need thereof, such as to ischemic myocardium. The invention further provides methods and systems for directing differentiation of expanded CD133+ cells. The invention further provides methods and systems for treating a subject with differentiated cells in a subject in need thereof.
    Type: Grant
    Filed: January 9, 2009
    Date of Patent: March 11, 2014
    Assignees: Arteriocyte Inc., Universite Pierre ET Marie Curie (Paris VI)
    Inventors: Ramasamy Sakthivel, Donald J. Brown, Hai-Quan Mao, Luc Douay, Vincent J. Pompili, Kevin McIntosh, Hiranmoy Das, Yukang Zhao
  • Biological therapeutic compositions and methods thereof
    Publication number: 20100183561
    Abstract: Novel uses of Platelet Rich Plasma (PRP) for infection prevention, bone repair and transmyocardial vascularization is disclosed. The present disclosure is directed to methods for preparing concentrated mesenchymal or haematopoietic stem cells, and autologous platelet-rich plasma (PRP) from the blood utilizing the Magallen® System. The stem cells and/or PRP may be combined with secondary biological agents such as antibiotics, fibrinogen and thrombin, and appropriately used in variety of medical conditions, such as, cardiovascular, thoracic, transplantation, head and neck, oral, gastrointestinal, orthopedic, neurosurgical, and plastic surgery.
    Type: Application
    Filed: July 7, 2009
    Publication date: July 22, 2010
    Applicant: ARTERIOCYTE MEDICAL SYSTEMS
    Inventors: Ramasamy Sakthivel, Donald J. Brown, Yukang Zhao, Adam Sorkin, Vincent Pompili, Kevin Mcintosh
  • METHODS AND SYSTEMS FOR EXPANDING AC133+ CELLS AND DIRECTING DIFFERENTIATION
    Publication number: 20090285892
    Abstract: The invention provides, among other things, methods and systems for expanding CD133+ cells. The invention further provides methods and systems for increasing the blood flow to an ischemic tissue in a subject in need thereof, such as to ischemic myocardium. The invention further provides methods and systems for directing differentiation of expanded CD133+ cells. The invention further provides methods and systems for treating a subject with differentiated cells in a subject in need thereof.
    Type: Application
    Filed: January 9, 2009
    Publication date: November 19, 2009
    Inventors: Ramasamy Sakthivel, Donald J. Brown, Hai-Quan Mao, Luc Douay, Vincent J. Pompili, Kevin Mclntosh, Hiranmoy Das, Yukang Zhao
  • Cell-based therapies for treating liver disease
    Publication number: 20080241246
    Abstract: The invention provides, in part, methods for treating liver disease in a subject in need thereof. The invention further provides methods for improving liver function in a subject in need thereof, such as a subject with an ischemic liver or a cirrhotic liver. In some aspects, the methods of treatment comprise the administration of AC133+ alone or in combination with other cell populations.
    Type: Application
    Filed: November 15, 2007
    Publication date: October 2, 2008
    Applicant: Arteriocyte Inc.
    Inventors: Ramasamy Sakthivel, Donald J. Brown, Vincent Pompili, Yukang Zhao