Patents by Inventor Ramaswamy Chandrashekar

Ramaswamy Chandrashekar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIVA (differentiate infected from vaccinated animals)
    Patent number: 8980274
    Abstract: The invention provides Ehrlichia canis antigens that can be used to detect E. canis infected animals regardless of whether the animals have been vaccinated for E. canis. The invention also provides compositions and methods for determining the presence of E. canis antigens and antibodies.
    Type: Grant
    Filed: January 21, 2011
    Date of Patent: March 17, 2015
    Assignee: IDEXX Laboratories, Inc.
    Inventors: Eugene Regis Krah, III, Melissa Beall, Thomas Patrick O'Connor, Jr., Ramaswamy Chandrashekar
  • (Aph) antigens and antibodies specific for
    Patent number: 8609350
    Abstract: The invention provides methods and compositions for the detection and treatment of Anaplasma phagocytophilum and Anaplasma platys infection.
    Type: Grant
    Filed: April 17, 2012
    Date of Patent: December 17, 2013
    Assignee: IDEXX Laboratories, Inc.
    Inventors: Jiayou Liu, Ramaswamy Chandrashekar
  • Anaplasma phagocytophilum (Aph) Antigens and Antibodies Specific for Anaplasma
    Publication number: 20120207779
    Abstract: The invention provides methods and compositions for the detection and treatment of Anaplasma phagocytophilum and Anaplasma platys infection.
    Type: Application
    Filed: April 17, 2012
    Publication date: August 16, 2012
    Inventors: Jiayou Liu, Ramaswamy Chandrashekar
  • () antigens and antibodies specific for
    Patent number: 8158370
    Abstract: The invention provides methods and compositions for the detection and treatment of Anaplasma phagocytophilum and Anaplasma platys infection.
    Type: Grant
    Filed: November 21, 2008
    Date of Patent: April 17, 2012
    Assignee: IDEXX Laboratories, Inc.
    Inventors: Jiayou Liu, Ramaswamy Chandrashekar
  • Ehrlichia canis DIVA (Differentiate Infected from Vaccinated Animals)
    Publication number: 20110182925
    Abstract: The invention provides Ehrlichia canis antigens that can be used to detect E. canis infected animals regardless of whether the animals have been vaccinated for E. canis. The invention also provides compositions and methods for determining the presence of E. canis antigens and antibodies.
    Type: Application
    Filed: January 21, 2011
    Publication date: July 28, 2011
    Inventors: Eugene Regis Krah III, Melissa Beall, Thomas Patrick O'Connor, JR., Ramaswamy Chandrashekar
  • Parasitic helminth cuticlin proteins and uses thereof
    Patent number: 7985591
    Abstract: The present invention relates to: parasitic helminth cuticlin proteins; parasitic helminth cuticlin nucleic acid molecules, including those that encode such cuticlin proteins; antibodies raised against such cuticlin proteins; and compounds that inhibit parasitic helminth cuticlin activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to protect animals from diseases caused by parasitic helminths.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: July 26, 2011
    Assignee: Heska Corporation
    Inventors: Ramaswamy Chandrashekar, Tony H. Morales
  • Detection of
    Patent number: 7906296
    Abstract: The invention provides compositions and methods for the detection of Anaplasma platys polynucleotides and polypeptides.
    Type: Grant
    Filed: February 10, 2009
    Date of Patent: March 15, 2011
    Assignee: IDEXX Laboratories, Inc.
    Inventors: Melissa Jane Beall, Phyllis Ione Tyrrell, Ramaswamy Chandrashekar, Jiayou Liu
  • DIVA (differentiate infected from vaccinated animals)
    Patent number: 7888054
    Abstract: The invention provides Ehrlichia canis antigens that can be used to detect E. canis infected animals regardless of whether the animals have been vaccinated for E. canis. The invention also provides compositions and methods for determining the presence of E. canis antigens and antibodies.
    Type: Grant
    Filed: October 31, 2008
    Date of Patent: February 15, 2011
    Assignee: IDEXX Laboratories, Inc.
    Inventors: Eugene Regis Krah, III, Melissa Beall, Thomas Patrick O'Connor, Jr., Ramaswamy Chandrashekar
  • Anaplasma Phagocytophilum (Aph) Antigens and Antibodies Specific for Anaplasma
    Publication number: 20110008380
    Abstract: The invention provides methods and compositions for the detection and treatment of Anaplasma phagocytophilum and Anaplasma platys infection.
    Type: Application
    Filed: November 21, 2008
    Publication date: January 13, 2011
    Applicant: IDEXX LABORATORIES, INC.
    Inventors: Jiayou Liu, Ramaswamy Chandrashekar
  • Peptides for detection of antibody to
    Patent number: 7696310
    Abstract: The invention provides compositions and methods for the detection and quantification of A. phagocytophilum (formerly known as Ehrlichia equi) antibodies and antibody fragments.
    Type: Grant
    Filed: September 16, 2008
    Date of Patent: April 13, 2010
    Assignee: IDEXX Laboratories, Inc.
    Inventors: Thomas Patrick O'Connor, Jr., Ramaswamy Chandrashekar
  • Detection of West Nile virus infection and vaccination
    Patent number: 7585621
    Abstract: A method and device for determining whether an animal is infected with West Nile Virus (WNV), or is either not infected or vaccinated with a WNV vaccine. The method includes contacting a biological sample from the subject with a first WNV polypeptide that is not an element of the WNV vaccine, and detecting whether antibodies in the sample bind to the WNV polypeptide. If the antibodies in the sample bind to the WNV polypeptide, it can be determined that the animal is naturally infected with WNV and if the antibodies do not bind to the polypeptide, it can be determined that the animal is either vaccinated or not infected.
    Type: Grant
    Filed: September 9, 2004
    Date of Patent: September 8, 2009
    Assignee: IDEXX Laboratories, Inc.
    Inventors: Melissa Beall, Ramaswamy Chandrashekar
  • DETECTION OF ANAPLASMA PLATYS
    Publication number: 20090155825
    Abstract: The invention provides compositions and methods for the detection of Anaplasma platys polynucleotides and polypeptides.
    Type: Application
    Filed: February 10, 2009
    Publication date: June 18, 2009
    Inventors: MELISSA JANE BEALL, PHYLLIS IONE TYRRELL, RAMASWAMY CHANDRASHEKAR, JIAYOU LIU
  • Ehrlichia canis DIVA (Differentiate Infected from Vaccinated Animals)
    Publication number: 20090110691
    Abstract: The invention provides Ehrlichia canis antigens that can be used to detect E. canis infected animals regardless of whether the animals have been vaccinated for E. canis. The invention also provides compositions and methods for determining the presence of E. canis antigens and antibodies.
    Type: Application
    Filed: October 31, 2008
    Publication date: April 30, 2009
    Inventors: Eugene Regis Krah, III, Melissa Beall, Thomas Patrick O'Connor, JR., Ramaswamy Chandrashekar
  • Detection of
    Patent number: 7507789
    Abstract: The invention provides compositions and methods for the detection of Anaplasma platys polynucleotides and polypeptides.
    Type: Grant
    Filed: April 9, 2007
    Date of Patent: March 24, 2009
    Assignee: IDEXX Laboratories, Inc.
    Inventors: Melissa Jane Beall, Phyllis Ione Tyrrell, Ramaswamy Chandrashekar, Jiayou Liu
  • Peptides for Detection of Antibody to Anaplasma phagocytophilum
    Publication number: 20090042222
    Abstract: The invention provides compositions and methods for the detection and quantification of A. phagocytophilum (formerly known as Ehrlichia equi) antibodies and antibody fragments.
    Type: Application
    Filed: September 16, 2008
    Publication date: February 12, 2009
    Inventors: Thomas Patrick O'Connor, JR., Ramaswamy Chandrashekar
  • PARASITIC HELMINTH CUTICLIN PROTEINS AND USES THEREOF
    Publication number: 20080280368
    Abstract: The present invention relates to: parasitic helminth cuticlin proteins; parasitic helminth cuticlin nucleic acid molecules, including those that encode such cuticlin proteins; antibodies raised against such cuticlin proteins; and compounds that inhibit parasitic helminth cuticlin activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to protect animals from diseases caused by parasitic helminths.
    Type: Application
    Filed: June 20, 2008
    Publication date: November 13, 2008
    Inventors: Ramaswamy Chandrashekar, Tony H. Morales
  • Peptides for detection of antibody to
    Patent number: 7439321
    Abstract: The invention provides compositions and methods for the detection and quantification of A. phagocytophilum (formerly known as Ehrlichia equi) antibodies and antibody fragments.
    Type: Grant
    Filed: January 11, 2005
    Date of Patent: October 21, 2008
    Assignee: IDEXX Laboratories, Inc.
    Inventors: Thomas O'Connor, Ramaswamy Chandrashekar
  • Detection of Anaplasma platys
    Publication number: 20080248497
    Abstract: The invention provides compositions and methods for the detection of Anaplasma platys polynucleotides and polypeptides.
    Type: Application
    Filed: April 9, 2007
    Publication date: October 9, 2008
    Inventors: Melissa Jane Beall, Phyllis Ione Tyrrell, Ramaswamy Chandrashekar, Jiayou Liu
  • Parasitic helminth cuticlin proteins and uses thereof
    Patent number: 7396536
    Abstract: The present invention relates to: parasitic helminth cuticlin proteins; parasitic helminth cuticlin nucleic acid molecules, including those that encode such cuticlin proteins; antibodies raised against such cuticlin proteins; and compounds that inhibit parasitic helminth cuticlin activity. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to protect animals from diseases caused by parasitic helminths.
    Type: Grant
    Filed: June 9, 2004
    Date of Patent: July 8, 2008
    Assignee: Heska Corporation
    Inventors: Ramaswamy Chandrashekar, Tony H. Morales
  • Detection of West Nile Virus
    Patent number: 7074555
    Abstract: A method and device for detecting a West Nile Virus (WNV) infection including contacting a biological sample from a subject with an anti-IgM antibody and a recombinant WNV E polypeptide and detecting whether the polypeptide substantially binds to an antibody in the sample. The invention also includes a method and device for determining whether an animal is infected with West Nile Virus (WNV), or is either not infected or is vaccinated with a WNV vaccine.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: July 11, 2006
    Assignee: IDEXX Laboratories, Inc.
    Inventors: Katherine Jean Esty, Ramaswamy Chandrashekar