Patents by Inventor Ramaswamy Kalyanasundaram

Ramaswamy Kalyanasundaram has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VACCINE AND METHODS FOR PREVENTING FILARIASIS AND DIROFILARIASIS
    Publication number: 20240115674
    Abstract: The present invention is a multivalent immunogenic composition for immunizing an animal against filariasis. In some aspects, the antigens of the multivalent immunogenic composition are protein-based, DNA-based, or a combination thereof. This invention also provides a method and kit for detecting a filarial nematode and determining vaccine efficacy.
    Type: Application
    Filed: February 2, 2022
    Publication date: April 11, 2024
    Inventors: Ramaswamy KALYANASUNDARAM, Darrick CARTER, Sean GRAY
  • VACCINE AND METHODS FOR DETECTING AND PREVENTING FILARIASIS
    Publication number: 20220332772
    Abstract: The present invention is a multivalent immunogenic composition for immunizing an animal against filariasis. In some embodiments, the antigens of the multivalent immunogenic composition are protein-based, DNA-based, or a combination thereof. This invention also provides a method and kit for detecting a filarial nematode and determining vaccine efficacy.
    Type: Application
    Filed: May 23, 2022
    Publication date: October 20, 2022
    Inventor: Ramaswamy KALYANASUNDARAM
  • Vaccine and methods for detecting and preventing filariasis
    Patent number: 11370814
    Abstract: The present invention is a multivalent immunogenic composition for immunizing an animal against filariasis. In some embodiments, the antigens of the multivalent immunogenic composition are protein-based, DNA-based, or a combination thereof. This invention also provides a method and kit for detecting a filarial nematode and determining vaccine efficacy.
    Type: Grant
    Filed: February 13, 2020
    Date of Patent: June 28, 2022
    Assignee: The Board of Trustees of the University of Illinois
    Inventor: Ramaswamy Kalyanasundaram
  • VACCINE AND METHODS FOR DETECTING AND PREVENTING FILARIASIS
    Publication number: 20200172585
    Abstract: The present invention is a multivalent immunogenic composition for immunizing an animal against filariasis. In some embodiments, the antigens of the multivalent immunogenic composition are protein-based, DNA-based, or a combination thereof. This invention also provides a method and kit for detecting a filarial nematode and determining vaccine efficacy.
    Type: Application
    Filed: February 13, 2020
    Publication date: June 4, 2020
    Inventor: Ramaswamy KALYANASUNDARAM
  • VACCINE AND METHODS FOR DETECTING AND PREVENTING FILARIASIS
    Publication number: 20190040108
    Abstract: The present invention is a multivalent vaccine for immunizing an animal against filariasis. In some embodiments, the antigens of the multivalent vaccine are protein-based, DNA-based, or a combination thereof. This invention also provides a method and kit for detecting a filarial nematode and determining vaccine efficacy.
    Type: Application
    Filed: August 29, 2018
    Publication date: February 7, 2019
    Inventor: Ramaswamy Kalyanasundaram
  • Vaccine and methods for detecting and preventing filariasis
    Patent number: 10072054
    Abstract: The present invention is a multivalent vaccine for immunizing an animal against filariasis. In some embodiments, the antigens of the multivalent vaccine are protein-based, DNA-based, or a combination thereof. This invention also provides a method and kit for detecting a filarial nematode and determining vaccine efficacy.
    Type: Grant
    Filed: July 14, 2015
    Date of Patent: September 11, 2018
    Assignee: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventor: Ramaswamy Kalyanasundaram
  • VACCINE AND METHODS FOR DETECTING AND PREVENTING FILARIASIS
    Publication number: 20150307566
    Abstract: The present invention is a multivalent vaccine for immunizing an animal against filariasis. In some embodiments, the antigens of the multivalent vaccine are protein-based, DNA-based, or a combination thereof. This invention also provides a method and kit for detecting a filarial nematode and determining vaccine efficacy.
    Type: Application
    Filed: July 14, 2015
    Publication date: October 29, 2015
    Applicant: The Board of Trustees of the University of Illinois
    Inventor: Ramaswamy Kalyanasundaram
  • Multivalent Vaccine for Filariasis
    Publication number: 20130236490
    Abstract: The present invention is a multivalent vaccine for immunizing an animal against filariasis. In some embodiments, the antigens of the multivalent vaccine are protein-based, DNA-based, or a combination thereof.
    Type: Application
    Filed: November 7, 2011
    Publication date: September 12, 2013
    Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventor: Ramaswamy Kalyanasundaram
  • Parasite-derived anti-inflammatory immunomodulatory protein
    Publication number: 20050037970
    Abstract: A protein with anti-inflammatory, and immunomodulatory functions was identified and isolated from the excretory/secretions of a human parasite, Schistosoma mansoni. This protein, designated herein as Sm 16.8, is released by schistosomes upon entry into human skin. Under in vitro conditions Sm 16.8 is shown to stimulate the production of anti-inflammatory cytokine Interleukin-1 receptor antagonist (IL-1ra) in human keratinocytes and transcriptionally down regulate the production of pro-inflamnmatory cytokines IL-1 and IL-1.
    Type: Application
    Filed: September 20, 2004
    Publication date: February 17, 2005
    Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Bernard Salafsky, Ramaswamy Kalyanasundaram, Takeshi Shibuya
  • Parasite-derived anti-inflammatory immunomodulatory protein
    Publication number: 20020176862
    Abstract: A protein with anti-inflammatory, and immunomodulatory functions was identified and isolated from the excretory/secretions of a human parasite, Schistosoma mansoni. This protein, designated herein as Sm 16.8, is released by schistosomes upon entry into human skin. Under in vitro conditions Sm 16.8 is shown to stimulate the production of anti-inflammatory cytokine Interleukin-1 receptor antagonist (IL-1ra) in human keratinocytes and transcriptionally down regulate the production of pro-inflammatory cytokines IL-1 and IL-1.
    Type: Application
    Filed: April 2, 2002
    Publication date: November 28, 2002
    Applicant: The Board of Trustees of the University of Illinois
    Inventors: Bernard Salafsky, Ramaswamy Kalyanasundaram, Takeshi Shibuya
  • Anti-parasitic action of N,N-diethyl-m-toluamide (deet) and formulations that prolong its activity in the skin
    Patent number: 6447801
    Abstract: Novel formulations of DEET are provided which comprise liposomes and other carriers. Methods and materials for preventing Schistomiasis and other parasitic and microbial diseases are also provided. Also provided are improved materials and methods for repelling biting insects.
    Type: Grant
    Filed: April 1, 1999
    Date of Patent: September 10, 2002
    Inventors: Bernard Salafsky, Ramaswamy Kalyanasundaram, Takeshi Shibuya
  • Parasite-derived anti-inflammatory immunomodulatory protein
    Patent number: 6372219
    Abstract: A protein with anti-inflammatory, and immunomodulatory functions was identified and isolated from the excretory/secretions of a human parasite Schistosoma mansoni. This protein, designated herein as Sm 16.8, is released by schistosomes upon entry into human skin. Under in vitro conditions Sm 16.8 is shown to stimulate the production of anti-inflammatory cytokine Interleukin-1 receptor antagonist (IL-1ra) in human keratinocytes and transciptionally down regulate the production of proinflammatory cytokines IL-1 &agr; and IL-1 &bgr;.
    Type: Grant
    Filed: October 19, 1999
    Date of Patent: April 16, 2002
    Inventors: Bernard Salafsky, Ramaswamy Kalyanasundaram, Takeshi Shibuya