Patents by Inventor Ramegowda Thimmegowda Naraganahalli

Ramegowda Thimmegowda Naraganahalli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition for prevention or treatment of cancer comprising N-methylenenaphtho[2,1-]furan-2-carbohydrazide derivatives as an active ingredient
    Patent number: 9433607
    Abstract: The present invention relates to ethyl(2-methyl-3{(E)-[(naphtho[2,1-b]furan-2-ylcarbonyl)hydrazono]methyl}-1H-indole-1-yl)acetate, the novel mitosis inhibitor. The said ethyl(2-methyl-3{(E)-[(naphtho[2,1-b]furan-2-ylcarbonyl)hydrazono]methyl}-1H-indole-1-yl)acetate not only induces apoptosis by inhibiting tubulin polymerization in the course of mitosis but also displays an excellent anticancer effect in the multi-drug resistant cancer cells, so that it can be effectively used for the treatment of cell proliferative disease including various cancers.
    Type: Grant
    Filed: March 6, 2015
    Date of Patent: September 6, 2016
    Assignee: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Bo Yeon Kim, Krisada Sakchaisri, Sun Ok Kim, Ramegowda Thimmegowda Naraganahalli, Nak Kyun Soung, Jong Seog Ahn, Joonsung Hwang, In Ja Ryoo, Jae-Hyuk Jang
  • COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER COMPRISING N-METHYLENENAPHTHO[2,1-b]FURAN-2-CARBOHYDRAZIDE DERIVATIVES AS AN ACTIVE INGREDIENT
    Publication number: 20150182502
    Abstract: The present invention relates to ethyl(2-methyl-3{(E)-[(naphtho[2,1-b]furan-2-ylcarbonyl)hydrazono]methyl}-1H-indole-1-yl)acetate, the novel mitosis inhibitor. The said ethyl(2-methyl-3{(E)-[(naphtho[2,1-b]furan-2-ylcarbonyl)hydrazono]methyl}-1H-indole-1-yl)acetate not only induces apoptosis by inhibiting tubulin polymerization in the course of mitosis but also displays an excellent anticancer effect in the multi-drug resistant cancer cells, so that it can be effectively used for the treatment of cell proliferative disease including various cancers.
    Type: Application
    Filed: March 6, 2015
    Publication date: July 2, 2015
    Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Bo Yeon Kim, Krisada Sakchaisri, Sun Ok Kim, Ramegowda Thimmegowda Naraganahalli, Nak Kyun Soung, Jong Seog Ahn, Joonsung Hwang, In Ja Ryoo, Jae-Hyuk Jang