Patents by Inventor RameshBabu Boga
RameshBabu Boga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180317484Abstract: A composition for inhibiting the growth of mycotoxins without affecting the growth of fungi is provided. The mycotoxin is an Aflatoxin and the fungus is an Aspergillus. The anti-aflatoxin composition comprises benzimidazole derivatives of Formula, where the A is hydrogen or C1-C6 alkyl or C6-C14 aryl; B is C1-C10 alkyl or C6-C14 aryl or oxygen, sulfur, nitrogen containing heteroaryl; C and D are hydrogen or C1-C6 alkyl or C1-C6 alkoxyl or C6-C14 aryl; E is hydrogen or nitro or cyano or carboxyl or acetamidoxime or amidoxime or C1-C6 alkyl or C1-C6 alkoxyl or C6-C14 aryl or oxygen, sulfur, and nitrogen containing heteroaryl; F is hydrogen or C1-C6 alkyl or C1-C6 alkoxyl or C6-C14 aryl or oxygen, sulfur, and nitrogen containing heteroaryl, and mixture thereof with corresponding salts.Type: ApplicationFiled: April 20, 2018Publication date: November 8, 2018Inventors: Alka Mehta, RameshBabu Boga, Dhanamjayulu P
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Patent number: 9279140Abstract: There is provided a personal care product having a body side liner, a baffle and an indicator strip with two ends. The indicator has an amine sensitive dye near at least one end. The indicator extends from the target area just below the liner to just above the baffle such that the dye deposit is visible to an unaided eye. The dye changes color in the presence of amines which are characteristic of infection, thus alerting the user to the possibility of infection. Such an indicator placed in a feminine hygiene pad, for example, may be useful in the diagnosis of vaginitis.Type: GrantFiled: August 26, 2013Date of Patent: March 8, 2016Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Rameshbabu Boga, John Gavin MacDonald
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Patent number: 8901366Abstract: In accordance with one embodiment of the present disclosure, a method for quantitatively or semi-quantitatively determining the volume of a test sample of urine is provided. The method includes contacting the test sample with a fluidic medium of a lateral flow device having a volume indicator disposed thereon and determining the volume of urine in the test sample based on the distance traveled by the volume indicator along the fluidic medium, the distance traveled by the volume indicator corresponding to the volume of urine in the test sample.Type: GrantFiled: December 14, 2007Date of Patent: December 2, 2014Assignee: Kimberly Clark Worldwide, Inc.Inventors: Xuedong Song, RameshBabu Boga, Ning Wei
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Patent number: 8702618Abstract: The invention provides a breath testing device which includes a visual indicating agent which changes color in the presence of an odor associated with bad breath, such as sulfur and ammonia odors. An example of the visual indicating agent is 4,4?-bis(dimethylamino)-benzhydrol (Michler's hydrol or BDMB) and related dyes having a similar chemical structure. The indicating agent is applied to a substrate which is then inserted into a tube or straw, or which covers one end of a straw. When a user with bad breath blows into the tube or straw, the indicating agent will change color. The breath testing devices provide a quick and affordable means for a user to test their breath, and they may be packaged in discreet, pocket-sized dispensers which can be carried in a pocket or purse.Type: GrantFiled: July 16, 2012Date of Patent: April 22, 2014Assignee: Kimberly-Clark Worldwide, Inc.Inventors: John Gavin MacDonald, Kevin P. McGrath, RameshBabu Boga
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Patent number: 8703179Abstract: A mucosal formulation for administration to mucosal membranes, such as in the mouth, nasal passage, stomach, vagina, etc., is disclosed. The mucosal formulation contains a lipid-pharmaceutical agent complex formed from phospholipids possessing a hydrophobic moiety that orients into a hydrophobic phase and a polar head moiety that orients towards the aqueous phase (i.e., “amphipathic” lipids). When placed in an aqueous medium (e.g., vaginal fluid), the phospholipids form liposomes or other small lipid vesicles (e.g., micelles) that may then be used to deliver pharmaceutical agents into a living organism.Type: GrantFiled: May 11, 2006Date of Patent: April 22, 2014Assignee: Kimberly-Clark Worldwide, Inc.Inventors: RameshBabu Boga, Robert B. Johnson
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Publication number: 20140087417Abstract: There is provided a personal care product having a body side liner, a baffle and an indicator strip with two ends. The indicator has an amine sensitive dye near at least one end. The indicator extends from the target area just below the liner to just above the baffle such that the dye deposit is visible to an unaided eye. The dye changes color in the presence of amines which are characteristic of infection, thus alerting the user to the possibility of infection. Such an indicator placed in a feminine hygiene pad, for example, may be useful in the diagnosis of vaginitis.Type: ApplicationFiled: August 26, 2013Publication date: March 27, 2014Applicant: Kimberly-Clark Worldwide, Inc.Inventors: Rameshbabu Boga, John Gavin MacDonald
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Publication number: 20130261486Abstract: The invention provides a breath testing device which includes a visual indicating agent which changes color in the presence of an odor associated with bad breath, such as sulfur and ammonia odors. An example of the visual indicating agent is 4,4?-bis(dimethylamino)-benzhydrol (Michler's hydrol or BDMB) and related dyes having a similar chemical structure. The indicating agent is applied to a substrate which is then inserted into a tube or straw, or which covers one end of a straw. When a user with bad breath blows into the tube or straw, the indicating agent will change color. The breath testing devices provide a quick and affordable means for a user to test their breath, and they may be packaged in discreet, pocket-sized dispensers which can be carried in a pocket or purse.Type: ApplicationFiled: July 16, 2012Publication date: October 3, 2013Applicant: KIMBERLY-CLARK WORLDWIDE, INC.Inventors: John Gavin MacDonald, Kevin Peter McGrath, RameshBabu Boga
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Patent number: 8518374Abstract: There is provided a personal care product having a body side liner, a baffle and an indicator strip with two ends. The indicator has an amine sensitive dye near at least one end. The indicator extends from the target area just below the liner to just above the baffle such that the dye deposit is visible to an unaided eye. The dye changes color in the presence of amines which are characteristic of infection, thus alerting the user to the possibility of infection. Such an indicator placed in a feminine hygiene pad, for example, may be useful in the diagnosis of vaginits.Type: GrantFiled: February 6, 2009Date of Patent: August 27, 2013Assignee: Kimberly-Clark Worldwide, Inc.Inventors: RameshBabu Boga, John Gavin MacDonald
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Patent number: 8221328Abstract: The invention provides a breath testing device which includes a visual indicating agent which changes color in the presence of an odor associated with bad breath, such as sulfur and ammonia odors. An example of the visual indicating agent is 4,4?-bis(dimethylamino)-benzhydrol (Michler's hydrol or BDMB) and related dyes having a similar chemical structure. The indicating agent is applied to a substrate which is then inserted into a tube or straw, or which covers one end of a straw. When a user with bad breath blows into the tube or straw, the indicating agent will change color. The breath testing devices provide a quick and affordable means for a user to test their breath, and they may be packaged in discreet, pocket-sized dispensers which can be carried in a pocket or purse.Type: GrantFiled: June 6, 2008Date of Patent: July 17, 2012Assignee: Kimberly-Clark Worldwide, Inc.Inventors: John Gavin MacDonald, Kevin P. McGrath, RameshBabu Boga
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Patent number: 8043821Abstract: The invention provides methods for identifying antibody preparations that can form a pair of antibodies that optimally detect a target antigen, for example, in a sandwich immunoassay. These methods provide high affinity and epitope-specific antibodies.Type: GrantFiled: April 6, 2009Date of Patent: October 25, 2011Assignee: Kimberly-Clark Worldwide, Inc.Inventor: RameshBabu Boga
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Patent number: 8012761Abstract: A method for rapidly detecting the presence of formaldehyde in a urine sample (e.g., urine or a urinary material associated therewith, such as headspace gas located associated with urine) is provided. The method includes contacting the urine sample with a substrate on which is disposed a colorant that is capable of undergoing a detectable color change in the presence of formaldehyde. Without intending to be limited by theory, it is believed that oxidation of the colorant by formaldehyde induces either a shift of the absorption maxima towards the red end of the spectrum (“bathochromic shift”) or towards the blue end of the spectrum (“hypsochromic shift”). The absorption shift provides a color difference that is detectable, either visually or through instrumentation, to indicate the presence of formaldehyde within the urine sample. For example, prior to contact with a urine sample, the colorant may be colorless or it may possess a certain color.Type: GrantFiled: December 14, 2006Date of Patent: September 6, 2011Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Rameshbabu Boga, Stephanie M. Martin, Molly K. Smith, Kevin Peter McGrath
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Patent number: 7977103Abstract: A method for detecting the onset of ovulation in a female mammal is provided. The method includes contacting mouth air of the female mammal with an arylmethane test chromogen in an amount effective to undergo a rapid and detectable color change in the presence of one or more volatile sulfur compounds. The color of the test chromogen is compared to a control color that corresponds to a pre-ovulatory sulfur content. The difference in color between the test chromogen and the control color is correlated to the onset of ovulation.Type: GrantFiled: April 20, 2006Date of Patent: July 12, 2011Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Stephanie Michelle Martin, RameshBabu Boga, John Gavin MacDonald
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Patent number: 7964340Abstract: A technique for detecting the presence or quantity of an enzyme (or enzyme inhibitor) and/or an amine within a test sample is provided. For example, in one embodiment, a diagnostic test kit is employed that utilizes reactive complexes that each includes a substrate joined (e.g., covalently bonded, physically adsorbed, etc.) to a reporter and a separation species. Upon contacting the reactive complexes, enzymes may cleave the substrate and release the reporter. Moreover, the test kit may also employ a chemichromic dye, i.e., a dye that exhibits a detectable color change upon chemical reaction with one or more functional groups, such as amino groups. The signal generated (directly or indirectly) by the reporter and chemichromic dye may then be used to indicate the presence or quantity of an enzyme (or enzyme inhibitor) and amine, respectively, within the test sample.Type: GrantFiled: April 21, 2009Date of Patent: June 21, 2011Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Xuedong Song, RameshBabu Boga, Chibueze Obi Chidebelu-Eze
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Patent number: 7943395Abstract: A flow-through assay device for detecting the presence or quantity of an analyte residing in a test sample is provided. The device utilizes multiple detection zones, one of which is premised on “competitive” binding of the analyte and the other is premised on “sandwich” binding of the analyte. The present inventors believe that the combination of these zones may enable the detection of an analyte over extended concentration ranges.Type: GrantFiled: November 21, 2003Date of Patent: May 17, 2011Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Ning Wei, Rameshbabu Boga
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Patent number: 7837663Abstract: The present invention relates to a visual indicating device and an article for controlling odors, in particular foot, garbage, basement, cooking, pet, tobacco, feces and urine odors. The article comprises a visual indicating agent that is color sensitive to the odor, and optionally, an odor absorbing agent. The visual indicating agent changes color when the article has been exposed to a sufficient amount of odor to saturate the article. The indicating agent may be applied in differing concentrations to two or more zones so as to indicate to a user of the article how much of the odor absorbing capacity has been used, or conversely, how much of the odor absorbing capacity remains. Suitable visual indicating agents that change color in response to odors are also described. The article for controlling odors may be a disposable odor absorbing sheet, air freshening product, diaper, undergarment pad, face mask, air filtration device, sanitary napkin, tampon, panty shield or incontinence pad.Type: GrantFiled: October 16, 2003Date of Patent: November 23, 2010Assignee: Kimberly-Clark Worldwide, Inc.Inventors: John Gavin MacDonald, RameshBabu Boga, Jaeho Kim, Bao Trong Do, Irene Kuznetsov
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Patent number: 7814582Abstract: A system for detecting an actual or impending overflow condition from a washroom fixture includes an overflow sensor configured with the fixture at a location to detect an abnormal rise in water level within the fixture before water overflows the fixture. A water sensor may also be disposed to detect an abnormal amount of water on the washroom floor. A data communications unit is in communication with the sensors. A washroom monitoring station is provided in wireless communication with the data communications unit and in communication with the sensors through the data communications unit. The washroom monitoring station is configured for indicating the presence of water when detected by the overflow or water sensors.Type: GrantFiled: June 29, 2005Date of Patent: October 19, 2010Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Kiran K. Reddy, Joseph Mitchell, Cheryl L. York, Amanda Butler, Debra N. Welchel, Rameshbabu Boga, James J. Detamore, Ronald R. Padak, Jason Lye
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Patent number: 7645583Abstract: Disclosed are screening processes for identification of compounds that may inhibit complex formation between C-reactive protein and fibronectin. Compounds identified by the disclosed methods may be utilized to inhibit the target analytes that are known to occur during skin aging as well as during the course of several diseases. Accordingly, inhibitory compounds identified by the disclosed methods may be utilized to prevent and treat damaged tissue, inflammatory conditions, cardiovascular conditions, renal conditions, periodontal conditions and obesity, among other conditions. For example, the compounds identified by the disclosed methods may be utilized to treat tissue that has suffered trauma, e.g., burns or wounds, as well as tissue that is inflamed due to any of several causes.Type: GrantFiled: December 14, 2005Date of Patent: January 12, 2010Assignee: Kimberly-Clark Worldwide, Inc.Inventors: RameshBabu Boga, Sohail Malik, Stephen Quirk
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Patent number: 7592020Abstract: There is provided a personal care product having a body side liner, a baffle and an indicator strip with two ends. The indicator has an amine sensitive dye near at least one end. The indicator extends from the target area just below the liner to just above the baffle such that the dye deposit is visible to an unaided eye. The dye changes color in the presence of amines which are characteristic of infection, thus alerting the user to the possibility of infection. Such an indicator placed in a feminine hygiene pad, for example, may be useful in the diagnosis of vaginitis.Type: GrantFiled: October 8, 2004Date of Patent: September 22, 2009Assignee: Kimberly-Clark Worldwide, Inc.Inventors: RameshBabu Boga, John Gavin MacDonald
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Publication number: 20090226938Abstract: A technique for detecting the presence or quantity of an enzyme (or enzyme inhibitor) and/or an amine within a test sample is provided. For example, in one embodiment, a diagnostic test kit is employed that utilizes reactive complexes that each includes a substrate joined (e.g., covalently bonded, physically adsorbed, etc.) to a reporter and a separation species. Upon contacting the reactive complexes, enzymes may cleave the substrate and release the reporter. Moreover, the test kit may also employ a chemichromic dye, i.e., a dye that exhibits a detectable color change upon chemical reaction with one or more functional groups, such as amino groups. The signal generated (directly or indirectly) by the reporter and chemichromic dye may then be used to indicate the presence or quantity of an enzyme (or enzyme inhibitor) and amine, respectively, within the test sample.Type: ApplicationFiled: April 21, 2009Publication date: September 10, 2009Applicant: KIMBERLY-CLARK WORLDWIDE, INC.Inventors: Xuedong Song, RameshBabu Boga, Chibueze Obi Chidebelu-Eze
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Patent number: 7582485Abstract: The invention provides a breath testing device which visually indicates the presence of ammonia in a patient's breath, in particular ammonia from helicobacter pylori urease infection. The breath testing device comprises a visual indicating agent which changes color in response to ammonia odors, such as 4,4?-bis(dimethylamino)-benzhydrol (Michler's hydrol or BDMB), pararosaniline base and alpha-naphtholbenzein. The indicating agent is applied to a substrate which is then inserted into a tube or straw, which can be attached to the inlet of a breath collection balloon. When the patient blows into the tube or straw, the indicating agent will change color if it detects levels of ammonia which are consistent with helicobacter pylori urease infection.Type: GrantFiled: October 16, 2003Date of Patent: September 1, 2009Assignee: Kimberly-Clark Worldride, Inc.Inventors: RameshBabu Boga, John Gavin MacDonald