Patents by Inventor Ramesh Dandala

Ramesh Dandala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PREPARATION OF HIGH PURE ERIBULIN AND ITS MESYLATE SALT
    Publication number: 20220089607
    Abstract: The present invention relates to a process for the preparation of high pure Eribulin and Eribulin Mesylate. The present invention involves preparation of high pure Eribulin and its mesylate salt involving chiral acid addition salts of Eribulin.
    Type: Application
    Filed: November 27, 2019
    Publication date: March 24, 2022
    Inventors: Prabhakar DIVYA, Srinivasu KASA, Durga Prasad KONAKANCHI, Ramesh DANDALA, Pulla Reddy MUDDASANI, Venkaiah Chowdary NANNAPANENI
  • Process for the preparation of velpatasvir
    Patent number: 10487067
    Abstract: The present disclosure provides a process for the preparation of velpatasvir intermediates. The intermediates may be further converted to velpatasvir or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: November 26, 2019
    Assignee: MYLAN LABORATORIES LIMITED
    Inventors: Lakshmana Rao Vadali, Sureshbabu Jayachandra, Rajasekhar Ponduri, Bhaskar Rao Padala, Eswara Reddy Yerva, Govardhana Phani Sharma Vemavarapu, Ravikanth Jaldu, Ramesh Dandala
  • Premix of crystalline raltegravir potassium salt and a process for the preparation thereof
    Patent number: 10391178
    Abstract: The present disclosure provides a process for the preparation a premix of raltegravir potassium form 3 with excipients. This premix may be used in the manufacture of pharmaceutical formulations containing raltegravir.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: August 27, 2019
    Assignee: Mylan Laboratories Limited
    Inventors: Ramesh Dandala, Sivarama Prasad Vellanki, Raja Babu Balusu, Subbarayudu Putta
  • Process for the enantiomeric resolution of apremilast intermediates
    Patent number: 10370329
    Abstract: A process for the resolution of racemic 2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulphonyl)-eth-2-ylamine using novel chiral salts is disclosed. An L-phenylalanine p-toluene-sulfonamide salt of (S)-2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulphonyl)-eth-2-ylamine and a di-p-toluoyl-L-tartaric acid salt of (S)-2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulphonyl)-eth-2-ylamine are also provided.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: August 6, 2019
    Inventors: Ramesh Dandala, Sureshbabu Jayachandra, Vipin Kumar Kaushik, Nageshwara Rao Achanta, Sivaprasad Dorasala
  • Process for the Preparation of Velpatasvir
    Publication number: 20180282294
    Abstract: The present disclosure provides a process for the preparation of velpatasvir intermediates. The intermediates may be further converted to velpatasvir or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: October 5, 2016
    Publication date: October 4, 2018
    Applicant: Mylan Laboratories Limited
    Inventors: Lakshmana Rao Vadali, Sureshbabu Jayachandra, Rajasekhar Ponduri, Bhaskar Rao Padala, Eswara Reddy Yerva, Govardhana Phani Sharma Vemavarapu, Ravikanth Jaldu, Ramesh Dandala
  • APREMIX OF CRYSTALLINE RALTEGRAVIR POTASSIUM SALT AND A PROCESS FOR THE PREPARATION THEREOF
    Publication number: 20180169245
    Abstract: The present disclosure provides a process for the preparation a premix of raltegravir potassium form 3 with excipients. This premix may be used in the manufacture of pharmaceutical formulations containing raltegravir.
    Type: Application
    Filed: March 20, 2015
    Publication date: June 21, 2018
    Inventors: Ramesh DANDALA, Sivarama Prasad VELLANKI, Raja Babu BALUSU, Subbarayudu PUTTA
  • Preparation of cobicistat intermediates
    Patent number: 9975864
    Abstract: The present disclosure provides crystalline piperidine sulfamoyl intermediates of formula 8 and 9. The present disclosure also relates to an improved process for the preparation of cobicistat using compounds of formulae 8 and 9.
    Type: Grant
    Filed: December 2, 2014
    Date of Patent: May 22, 2018
    Assignee: Mylan Laboratories Limited
    Inventors: Lakshmana Rao Vadali, Rameshbabu Konda, Ramesh Dandala
  • PROCESS FOR THE ENANTIOMERIC RESOLUTION OF APREMILAST INTERMEDIATES
    Publication number: 20180134660
    Abstract: A process for the resolution of racemic 2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulphonyl)-eth-2-ylamine using novel chiral salts is disclosed. An L-phenylalanine p-toluene-sulfonamide salt of (S)-2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulphonyl)-eth-2-ylamine and a di-p-toluoyl-L-tartaric acid salt of (S)-2-(3-ethoxy-4-methoxyphenyl)-1-(methylsulphonyl)-eth-2-ylamine are also provided.
    Type: Application
    Filed: April 22, 2016
    Publication date: May 17, 2018
    Applicant: Mylan Laboratories Limited
    Inventors: Ramesh Dandala, Sureshbabu Jayachandra, Vipin Kumar Kaushik, Nageshwara Rao Achanta, Sivaprasad Dorasala
  • Preparation of Cobicistat Intermediates
    Publication number: 20160297780
    Abstract: The present disclosure provides crystalline piperidine sulfamoyl intermediates of formula 8 and 9. The present disclosure also relates to an improved process for the preparation of cobicistat using compounds of formulae 8 and 9.
    Type: Application
    Filed: December 2, 2014
    Publication date: October 13, 2016
    Inventors: Lakshmana Rao VADALI, Rameshbabu KONDA, Ramesh DANDALA
  • Process for the preparation of aliskiren
    Patent number: 9090537
    Abstract: The present invention relates to an improved process for the preparation of pure compound of Formula-II, which is an intermediate in the preparation of Aliskiren and further conversion of compound of Formula-II into Aliskiren or its pharmaceutically acceptable salts.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: July 28, 2015
    Assignee: Mylan Laboratories Limited
    Inventors: Shankar Rama, Seshadri Rao Manukonda, Srinivasa Rao Dasari, Ramesh Dandala, Lakshmana Rao Vadali
  • Process for the manufacture of rosuvastatin calcium using crystalline rosuvastatin ethyl ester
    Patent number: 8846915
    Abstract: The present invention relates to an improved process to prepare Rosuvastatin calcium of Formula (I), with good quality. Further, the present invention also relates to a crystalline polymorphic form of Rosuvastatin ethyl ester.
    Type: Grant
    Filed: August 17, 2009
    Date of Patent: September 30, 2014
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Sambhu Prasad Sarma Mallela, Sukumar Nandi, Ganagadnar Bhima Shankar Nangi, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • PROCESS FOR THE PREPARATION OF 2-ARYLTHIAZOLE DERIVATIVES
    Publication number: 20130303780
    Abstract: The present invention relates an improved process for the preparation of 2-arylthiazole derivatives which are intermediates of Febuxostat and further conversion to Febuxostat or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: November 3, 2011
    Publication date: November 14, 2013
    Inventors: Siva Rama Prasad Vellanki, Arabinda Sahu, Satyanarayana Raavi, Ravi Nuchu, Ramesh Dandala
  • Process for preparing an optically active proton pump inhibitor
    Patent number: 8492551
    Abstract: An improved process for the preparation of (S)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole of Formula I, (I) with high enantiomeric excess from racemic mixture.
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: July 23, 2013
    Assignee: Aurobindo Pharma. Ltd.
    Inventors: Shankar Reddy Budidet, Brajesh Kumar Sinha, Somappa Somannavar Yallappa, Senthil Kumar Natarajan, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Process for preparing rosuvastatin calcium
    Patent number: 8318933
    Abstract: The present invention relates to an improved process for preparing Rosuvastatin calcium of Formula I.
    Type: Grant
    Filed: October 29, 2007
    Date of Patent: November 27, 2012
    Assignee: Aurobindo Pharma Ltd
    Inventors: Sambhu Prasad Sarma Mallela, Narayan K. A. S. S. Garimella, Sukumar Nandi, Sunil Kumar Buridipad, Gangadhar Bhima Shankar Nangi, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Process for the preparation of substantially pure (2S,3S,5S)-5-amino-2-N,N-dibenzylamino-3-hydroxy-1,6-diphenylhexane
    Patent number: 8236991
    Abstract: The present invention relates to the purification of (2S,3S,5S)-5-amino-2-N,N-dibenzylamino-3-hydroxy-1,6-diphenylhexane (III) by making its crystalline acid addition salt, which can be used as such to produce Lopinavir/Ritonavir with high purity and yield.
    Type: Grant
    Filed: June 5, 2008
    Date of Patent: August 7, 2012
    Assignee: Aurobindo Pharma Ltd.
    Inventors: V Raghava Reddy Ambati, Srinivas Garaga, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Process for preparing rosuvastatin calcium
    Patent number: 8212034
    Abstract: The present invention relates to an improved process for preparing (2E)-3-[4-(4-fluorophenyl)-6-iso-propyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-propenal of Formula I which is an intermediate useful in the preparation of bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoicacid]calcium salt of Formula II.
    Type: Grant
    Filed: December 11, 2007
    Date of Patent: July 3, 2012
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Ramesh Dandala, Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhar Bhima Shankar Nangi, Sunil Kumar Buridipadu, Sivakumaran Meenakshisunderam
  • Process for preparation of rosuvastatin calcium field of the invention
    Patent number: 8212035
    Abstract: The present invention relates to an improved process for preparing (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid calcium of Formula (I).
    Type: Grant
    Filed: February 4, 2008
    Date of Patent: July 3, 2012
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Ramesh Dandala, Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhar Bhima Shankar Nandi, Sunil Kumar Buridipadu, Sivakumaran Meenakshisunderam
  • Process for preparing nevirapine
    Patent number: 8212025
    Abstract: An improved process for preparing 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2?,3?-e][1,4]diazepin-6-one of Formula (I).
    Type: Grant
    Filed: May 14, 2008
    Date of Patent: July 3, 2012
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Jagan Mohan Reddy Sanapureddy, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • PROCESS FOR THE MANUFACTURE OF ROSUVASTATIN CALCIUM USING CRYSTALLINE ROSUVASTATIN ETHYL ESTER
    Publication number: 20120149905
    Abstract: The present invention relates to an improved process to prepare Rosuvastatin calcium of Formula (I), with good quality. Further, the present invention also relates to a crystalline polymorphic form of Rosuvastatin ethyl ester.
    Type: Application
    Filed: August 17, 2009
    Publication date: June 14, 2012
    Inventors: Sambhu Prasad Sarma Mallela, Sukumar Nandi, Gangadhara Bhima Shankar Nangi, Ramesh Dandala, Sivakumaran Meenakshisunderam
  • Process for the preparation of Irbesartan
    Patent number: 8106216
    Abstract: The present invention relates to an improved process for the preparation of 2-n-butyl-3-[[2?-(1H-tetrazol-5-yl)[1,1?-biphenyl]-4-yl]-1,3-diazaspiro[4.4]non-1-en-4-one (Irbesartan).
    Type: Grant
    Filed: April 23, 2007
    Date of Patent: January 31, 2012
    Assignee: Aurobindo Pharma Ltd.
    Inventors: Venkata vara prasada rao Korrapati, Venkata subramanyeswara rao Inti, Rani Ananta, Ramesh Dandala, Sivakumaran Meenakshisunderam