Patents by Inventor Ramesh M. Ray

Ramesh M. Ray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prevention of apoptosis in non-cancerous cells
    Patent number: 6936637
    Abstract: Treatment of normal, non-cancerous, animal cells with an agent that depletes polyamines within the cells results in an inhibition of apoptosis when the cells are exposed to an inducer of apoptosis. This inhibition of apoptosis is not observed, or is observed to a lesser extent, in similarly treated cancerous cells. The method of the invention is useful in obtaining preferential killing of cancer cells, as opposed to normal cells, due to anti-cancer therapy.
    Type: Grant
    Filed: October 1, 2002
    Date of Patent: August 30, 2005
    Assignee: University of Tennessee Research Foundation
    Inventors: Leonard R. Johnson, Ramesh M. Ray, Mary Jane Viar
  • Prevention of apoptosis in non-cancerous cells
    Publication number: 20030027866
    Abstract: Treatment of normal, non-cancerous, animal cells with an agent that depletes polyamines within the cells results in an inhibition of apoptosis when the cells are exposed to an inducer of apoptosis. This inhibition of apoptosis is not observed, or is observed to a lesser extent, in similarly treated cancerous cells. The method of the invention is useful in obtaining preferential killing of cancer cells, as opposed to normal cells, due to anti-cancer therapy.
    Type: Application
    Filed: October 1, 2002
    Publication date: February 6, 2003
    Inventors: Leonard R. Johnson, Ramesh M. Ray, Mary Jane Viar
  • Prevention of apoptosis in non-cancerous cells
    Patent number: 6498192
    Abstract: Treatment of normal, non-cancerous, animal cells with an agent that depletes polyamines within the cells results in an inhibition of apoptosis when the cells are exposed to an inducer of apoptosis. This inhibition of apoptosis is not observed, or is observed to a lesser extent, in similarly treated cancerous cells. The method of the invention is useful in obtaining preferential killing of cancer cells, as opposed to normal cells, due to anti-cancer therapy.
    Type: Grant
    Filed: August 28, 2000
    Date of Patent: December 24, 2002
    Assignee: The University of Tennessee Research Corporation
    Inventors: Leonard R. Johnson, Ramesh M. Ray, Mary Jane Viar