Abstract: An electrical connector system is provided and includes a connector housing including a base and a plurality of terminal cavities extending through the base. The base includes a retention shoulder within each terminal cavity. The electrical connector system includes terminals received in the corresponding terminal cavities. Each terminal includes a locking lance engaging the corresponding retention terminal to retain the terminal in the corresponding terminal cavity. Each locking lance includes a strengthening rib extending length-wise along the locking lance.

Abstract: A connector assembly having a connector housing with terminal receiving cavities which extend to a mating end of the connector housing. Electrical terminals are provided in the terminal receiving cavities. The terminals have mating portions which extend from the terminal receiving cavities beyond the mating end of the electrical connector. A movable cover is movably mounted on the connector housing. The movable cover extends over the mating portions of the terminals. The movable cover prevents unwanted engagement and damage to the mating portions of the terminals during shipping and assembly.

Abstract: A connector assembly has a first connector and a second connector. The first connector has a first connector housing. A lever is rotatably mounted relative to the first connector housing. The lever has lever arms with projections provided at free ends of the lever arms, The second connector has a second connector housing. A lever receiving recess with at least one latching projection is provided in the second connector housing. The at least one latching projection is configured to cooperate with the projections of the first connector housing. The lever is rotatable between a pre-insertion position and an insertion position. The cooperation of the lever with the lever receiving recess prevents the premature mating of the first connector housing to the second connector housing as the lever is moved between the pre-insertion position and the insertion position.

Abstract: An electrical connector assembly having a housing with terminal receiving cavities. First terminal position assurance receiving slots extend into the terminal receiving cavities. First terminals are positioned in the terminal receiving cavities. A cover is positioned over the housing, the cover has first terminal position assurance members which extend therefrom. The first terminal position assurance members of the cover extend through the first terminal position assurance receiving slots into the first terminal receiving cavities to properly position and retain the first terminals in the first terminal receiving cavities.

Abstract: Methods, computer program products, and systems can include obtaining a first computing environment specific application deployment software code instance associated to a first computing environment, the first computing environment specific application deployment software code instance for deployment of a certain application on the first computing environment; parsing the first computing environment specific application deployment software code instance, wherein the parsing includes determining attributes of the first computing environment specific application deployment software code instance and generating, using the determined attributes of the first computing environment specific application deployment software code instance, a computing environment agnostic semantic tree data structure that expresses a workflow pattern for deployment of the certain application; and composing, with use of the computing environment agnostic semantic tree data structure, a second computing environment specific application d

Abstract: The present invention provides high concentration solution formulations of anti-human interleukin-23 p19 (IL-23p19) antibody hum1388-b, and their use in treating various disorders.

Abstract: The invention is directed to stable and labile crosslinked water swellable polymeric microparticles that can be further gelled by covalent crosslinking in a transamidation reaction, methods for making same, and their various uses in the hygiene and medical arts, gel electrophoresis, packaging, agriculture, the cable industry, information technology, in the food industry, papermaking, use as flocculation aids, and the like. More particularly, the invention relates to a composition comprising expandable polymeric microparticles having labile crosslinkers and stable crosslinkers, said microparticle mixed with a fluid and an unreacted tertiary crosslinker comprising PEI or other polyamine based tertiary crosslinker that is capable of further crosslinking the microparticle on degradation of the labile crosslinker and swelling of the particle, so as to form a stable gel.

Abstract: Methods, computer program products, and systems can include obtaining a first computing environment specific application deployment software code instance associated to a first computing environment, the first computing environment specific application deployment software code instance for deployment of a certain application on the first computing environment; parsing the first computing environment specific application deployment software code instance, wherein the parsing includes determining attributes of the first computing environment specific application deployment software code instance and generating, using the determined attributes of the first computing environment specific application deployment software code instance, a computing environment agnostic semantic tree data structure that expresses a workflow pattern for deployment of the certain application; and composing, with use of the computing environment agnostic semantic tree data structure, a second computing environment specific application d

Abstract: An electrical connector includes a connector housing having a mounting end configured to be mounted to a circuit board and a cable exit end. The connector housing includes contact channels extending between the mounting end and the cable exit end. The connector housing includes a cover closing the contact channels. The electrical connector includes contacts received in the contact channels. Each contact includes a mating end and a cable end. The mating end is mated with the circuit board. The cable end is terminated to a cable. The cable exiting the connector housing at the cable exit end. The cable end is oriented at an angle relative to the mating end. The contact is formed in place in the contact channel.

Abstract: An electrical connector system is provided and includes a connector housing including a base and a plurality of terminal cavities extending through the base. The base includes a retention shoulder within each terminal cavity. The electrical connector system includes terminals received in the corresponding terminal cavities. Each terminal includes a locking lance engaging the corresponding retention terminal to retain the terminal in the corresponding terminal cavity. Each locking lance includes a strengthening rib extending length-wise along the locking lance.

Abstract: A method for determining a presence of arthritis in a patient, including obtaining a first image of a patient's joint, wherein the first image is a visible light image, obtaining a second image of the patient's joint, wherein the second image is a thermal light image, determining an outline of the patient's joint from the first image, determining an outline of a reference area from the first image, wherein the patient's joint is adjacent to the reference area, determining a first representative topological temperature within the outline of the patient's joint of the first image from the second image, determining a second representative topological temperature within the outline of the reference area of the first image from the second image, comparing the first representative topological temperature and the second representative topological temperature; and determining a likelihood of the presence of arthritis within the patient's joint.

Abstract: An electrical connector includes a housing having walls forming a cavity that receives a mating electrical connector. The walls include a base wall, side walls, and end walls. The base wall includes contact channels. The first side wall includes a slider slot open to the cavity. The electrical connector includes contacts held in the contact channels. The electrical connector includes a slider received in the slider slot and movable in a sliding direction within the slider slot. The slider includes a slider post extending into the cavity and movable within the cavity as the slider moves in the sliding direction. The slider post is configured to be received in a guide track of the mating electrical connector to locate the mating electrical connector within the cavity of the housing.

Abstract: The invention relates to stable formulations of antibodies against human programmed death receptor PD-1, or antigen binding fragments thereof. In some embodiments the formulations of the invention comprise between 5-200 mg/mL anti- PD-1 antibody, or antigen binding fragment thereof. The invention further provides methods for treating various cancers with stable formulations of the invention. In some embodiments of the methods of the invention, the formulations are administered to a subject by intravenous or subcutaneous administration.

Abstract: The present invention provides heterocyclic compounds of formula (I), which are therapeutically useful as CBP/EP300 inhibitors. These compounds are useful in the treatment and/or prevention of diseases or disorders mediated by CBP and/or EP300 in an individual. The present invention also provides preparation of the compounds and pharmaceutical compositions comprising at least one of the compounds of formula (I) or a pharmaceutically acceptable salt, or a stereoisomer or a tautomer, an N-oxide or an ester thereof.

Abstract: The disclosure provides an article comprising a substrate having a surface including (i) a matrix of an optically transparent polymeric material having a first surface functionality, and (ii) at least one plasma-treated surface region comprising a portion of the surface, wherein each surface region comprises a second surface functionality, and wherein the first surface functionality and the second surface functionality are different The disclosure also provides a method for forming an article, the method comprising: (a) providing a substrate having a surface including an optically transparent polymeric material, (b) contacting the surface with a first plasma to create at least one plasma-treated surface region comprising a portion of the surface, each plasma-treated surface region having a first surface functionality, and (c) contacting each plasma-treated surface region with a second plasma to create a second surface functionality.

Abstract: The invention relates to stable formulations of antibodies against human programmed death receptor PD-1, or antigen binding fragments thereof. In some embodiments the formulations of the invention comprise between 5-200 mg/mL anti-PD-1 antibody, or antigen binding fragment thereof. The invention further provides methods for treating various cancers with stable formulations of the invention. In some embodiments of the methods of the invention, the formulations are administered to a subject by intravenous or subcutaneous administration.

Abstract: A method for heat treating a powder metallurgy nickel-base alloy article comprises placing the article in a furnace at a start temperature in the furnace that is 80° C. to 200° C. below a gamma prime solvus temperature, and increasing the temperature in the furnace to a solution temperature at a ramp rate in the range of 30° C. per hour to 70° C. per hour. The article is solution treated for a predetermined time, and cooled to ambient temperature.

Abstract: An electrical connector having a connector housing and a lever. The connector housing has a first wall, a second wall and side walls which extend between the first wall and the second wall. Multiple contacts are positioned in contact receiving cavities of the housing. The multiple contacts have wires which extend therefrom. A lever is rotatably mounted relative to the connector housing. The lever has lever arms and a lever handle. The lever arms extend from the side walls of the housing and the lever handle extends between the lever arms. A wire guide is positioned on the lever. The lever is rotatable between a pre-insertion position and an insertion position. When the lever is in the insertion position, the wire guide engages the wires which extend from the housing to direct the wires to a designated position.

Abstract: The invention relates to stable formulations of antibodies against human programmed death receptor PD-1, or antigen binding fragments thereof. In some embodiments the formulations of the invention comprise between 5-200 mg/mL anti-PD-1 antibody, or antigen binding fragment thereof. The invention further provides methods for treating various cancers with stable formulations of the invention. In some embodiments of the methods of the invention, the formulations are administered to a subject by intravenous or subcutaneous administration.

Abstract: An electrical connector having a connector housing and a lever. The connector housing has a first wall, a second wall and side walls which extend between the first wall and the second wall. Multiple contacts are positioned in contact receiving cavities of the housing. The multiple contacts have wires which extend therefrom. A lever is rotatably mounted relative to the connector housing. The lever has lever arms and a lever handle. The lever arms extend from the side walls of the housing and the lever handle extends between the lever arms. A wire guide is positioned on the lever. The lever is rotatable between a pre-insertion position and an insertion position. When the lever is in the insertion position, the wire guide engages the wires which extend from the housing to direct the wires to a designated position.