Abstract: An I/O module configured to automatically detect a cold junction compensation (CJC) sensor includes a base and a removable terminal block (RTB). The RTB includes multiple terminals. An I/O circuit mounted within the base includes multiple contact pairs, where a first contact is mounted in the RTB and electrically connected to one of the terminals and a second contact is mounted in the base and electrically connected to the I/O circuit. A CJC sensor is mounted within the base proximate one of the second contacts and is operative to generate a feedback signal corresponding to a temperature present at the second contact. A controller in the I/O circuit generates a control signal to selectively connect the CJC sensor to an electrical ground connection. A switch connected between the CJC sensor and the electrical ground connection receives the control signal to selectively connect the CJC sensor to the electrical ground connection.

Abstract: A method of automating a workflow may include obtaining a completeness graph including conditions applied to attributes of an entity, determining that a missing attribute subset of the attributes lacks a corresponding value, determining that a condition corresponding to a missing attribute of the missing attribute subset is satisfied, and obtaining a value for the missing attribute. The value may be a result of performing a task in the workflow. The method may further include modifying a state of the entity by assigning the value to the missing attribute to obtain a modified state of the entity.

Abstract: Embodiments provide devices, systems and methods for preventing deep vein (DV) thrombosis (DVT). One embodiment provides a DVT prevention device including a cuff that fits over a patient's knee, an applanator coupled to an inside cuff surface, an expandable member (EM) coupled to the applanator, a pressure source fluidically coupled to the EM and a controller for controlling EM inflation. When the EM is inflated, it applies a force to the applanator which is transmitted to the knee back surface causing a popliteal vein (PV) under the cuff to be compressed so as to increase backpressure behind the compressed PV and subsequently increase the velocity of blood flow in the leg DVs when the EM is deflated. The EM can be inflated in a cycle including pulsed inflation, inflation hold and relaxation. The cycles can be repeated and adjusted to achieve a desired increase of blood flow/velocity in leg DVs.

Abstract: An I/O module includes an I/O base comprising a printed circuit board including I/O circuitry. A removable terminal block is removably connected to and selectively separable from the I/O base. The removable terminal block includes a plurality of field wiring terminals. The I/O module further includes a plurality of contact pairs each including: (i) a first constituent contact connected to the removable terminal block and electrically connected to one of said terminals; (ii) a second constituent contact connected to the I/O base and electrically connected to the I/O circuitry. A first CJC sensor is connected to the I/O base and is operatively connected to the I/O circuitry. The first CJC sensor is thermally associated with and adapted to sense a temperature of at least a first one of said second constituent contacts.

Abstract: Embodiments provide devices, systems and methods for preventing deep vein (DV) thrombosis (DVT). One embodiment provides a DVT prevention device including a cuff that fits over a patient's knee, an applanator coupled to an inside cuff surface, an expandable member (EM) coupled to the applanator, a pressure source fluidically coupled to the EM and a controller for controlling EM inflation. When the EM is inflated, it applies a force to the applanator which is transmitted to the knee back surface causing a popliteal vein (PV) under the cuff to be compressed so as to increase backpressure behind the compressed PV and subsequently increase the velocity of blood flow in the leg DVs when the EM is deflated. The EM can be inflated in a cycle including pulsed inflation, inflation hold and relaxation. The cycles can be repeated and adjusted to achieve a desired increase of blood flow/velocity in leg DVs.

Abstract: Systems and methods for identifying and extracting specific product usage patterns of potential customers and utilizing a machine learning evaluation model to predict the potential customers that are most likely to convert their subscriptions.

Abstract: A safety I/O module includes a plurality of output channels and a plurality of channel output terminals. The safety module further includes a multi-channel high side switch comprising an integrated circuit including a voltage input terminal and a plurality of main switches. A plurality of discrete safety switches are also provided. Each of the output channels includes a redundant pair of switches including one of the main switches of the multi-channel high side switch and one of the safety switches arranged in series. The main switch and the safety switch are configured to: (i) operably connect the voltage input terminal of the multi-channel high side switch to a respective one of the channel output terminals when both the main switch and the safety switch are in a conductive state; and (ii) disconnect the voltage input terminal of the multi-channel high side switch from the respective one of the channel output terminals when at least one of the main switch and the safety switch are in a non-conductive state.

Abstract: In one embodiment, a computer-implemented method for generating personalized photobooks for multiple entities with varying degrees of personalization at different levels of granularity is disclosed. The method includes generating a base template based on a content corpus. The base template may be transformed into a first dynamic template. Using at least the first dynamic template, the first personalized photobook may be generated for a first entity at a first level of granularity. The first dynamic template may be transformed into a second dynamic template. Using at least the first personalized photobook generated for the first entity at the first level of granularity and the second dynamic template, a second personalized photobook may be generated for a second entity at a second level of granularity. The second personalized photobook at the second level may be relatively more personalized than the first personalized photobook at the first level.

Abstract: The present invention describes an integrated apparatus that enables identification of invasive tumor cells directly from a specimen. The methods using the apparatus can be used to prognose or predict the survivability of the cancer in a subject and the risk of recurrence of the cancer in the subject after treatment. The methods disclosed herein can be used to determine which chemotherapeutic or other therapies most strongly inhibit the tumor cells invasiveness as a form of personalized therapy.

Abstract: Disclosed are UAP inhibitors to inhibit glucose flux in the hexosamine biosynthetic pathway and methods of treating a disease using the inhibitors.

Abstract: A method may include obtaining a knowledge graph including entities, and determining, for the knowledge graph, a first state including a first selectable entity subset of the entities that are selectable by a user. The first selectable entity subset may include an entity. The method may further include receiving, from the user and via a graphical user interface (GUI), a selection of the entity from the first selectable entity subset, and responsive to the selection, adding the entity to a report schema. The method further includes restricting, by the GUI, a space of selectable entities addable to the knowledge graph to the first selectable entity subset. The report schema may be used to populate a report. The method may further include, responsive to the selection, transitioning the knowledge graph to a second state including a second selectable entity subset of the entities that are selectable by the user.

Abstract: The present invention describes an integrated apparatus that enables identification of invasive tumor cells directly from a specimen. The methods using the apparatus can be used to prognose or predict the survivability of the cancer in a subject and the risk of recurrence of the cancer in the subject after treatment. The methods disclosed herein can be used to determine which chemotherapeutic or other therapies most strongly inhibit the tumor cells invasiveness as a form of personalized therapy.

Abstract: A method may include obtaining a knowledge graph including entities, and determining, for the knowledge graph, a first state including a first selectable entity subset of the entities that are selectable by a user. The first selectable entity subset may include an entity. The method may further include receiving, from the user and via a graphical user interface (GUI), a selection of the entity from the first selectable entity subset, and responsive to the selection, adding the entity to a report schema. The method further includes restricting, by the GUI, a space of selectable entities addable to the knowledge graph to the first selectable entity subset. The report schema may be used to populate a report. The method may further include, responsive to the selection, transitioning the knowledge graph to a second state including a second selectable entity subset of the entities that are selectable by the user.

Abstract: Embodiments provide devices, systems and methods for preventing deep vein (DV) thrombosis (DVT). One embodiment provides a DVT prevention device including a cuff that fits over a patient's knee, an applanator coupled to an inside cuff surface, an expandable member (EM) coupled to the applanator, a pressure source fluidically coupled to the EM and a controller for controlling EM inflation. When the EM is inflated, it applies a force to the applanator which is transmitted to the knee back surface causing a popliteal vein (PV) under the cuff to be compressed so as to increase backpressure behind the compressed PV and subsequently increase the velocity of blood flow in the leg DV's when the EM is deflated. The EM can be inflated in a cycle including pulsed inflation, inflation hold and relaxation. The cycles can be repeated and adjusted to achieve a desired increase of blood flow/velocity in leg DV's.

Abstract: A method may include obtaining a knowledge graph including entities, and determining, for the knowledge graph, a first state including a first selectable entity subset of the entities that are selectable by a user. The first selectable entity subset may include an entity. The method may further include receiving, from the user and via a graphical user interface (GUI), a selection of the entity from the first selectable entity subset, and responsive to the selection, adding the entity to a report schema. The report schema may be used to populate a report. The method may further include, responsive to the selection, transitioning the knowledge graph to a second state including a second selectable entity subset of the entities that are selectable by the user.

Abstract: A method of automating a workflow may include obtaining a completeness graph including conditions applied to attributes of an entity, determining that a missing attribute subset of the attributes lacks a corresponding value, determining that a condition corresponding to a missing attribute of the missing attribute subset is satisfied, and obtaining a value for the missing attribute. The value may be a result of performing a task in the workflow. The method may further include modifying a state of the entity by assigning the value to the missing attribute to obtain a modified state of the entity.

Abstract: The present invention provides compositions comprising Verteporfin and other anticancer compounds linked to a hydrophilic peptide through a degradable linker molecule to allow the anticancer compounds to penetrate tissues via in situ administration. The compounds of the present invention are useful for sensitizing tumor cells to radiotherapy, preventing recurrence of tumors after surgical resection and for treating remaining unremoved cancer cells at the site of the tumor.

Abstract: A system for identifying amygdala hyperactivity in a human patient includes a network-connected mobile apparatus associated with the user. The network-connected mobile apparatus may be used to accept mood, energy and behavior input from the user and to accept third party patient observation data via the network. The network-connected device may be further used to accept provider-labeled patient observation data via the network and to provide behavioral suggestions to the user based on a set of profile rules. The profile rules may be generated from the behavior input from the user, the third-party patient observation data, and provider-labeled patient observation data as processed by a machine-learning system.

Abstract: An input module may include a first resistor and a second resistor coupled in series with the first resistor. The input module may also include a switch that may electrically isolate the second resistor based on a voltage output by an additional input module electrically coupled to the input module via a terminal base.

Abstract: Embodiments provide devices, systems and methods for preventing deep vein (DV) thrombosis (DVT). One embodiment provides a DVT prevention device including a cuff that fits over a patient's knee, an applanator coupled to an inside cuff surface, an expandable member (EM) coupled to the applanator, a pressure source fluidically coupled to the EM and a controller for controlling EM inflation. When the EM is inflated, it applies a force to the applanator which is transmitted to the knee back surface causing a popliteal vein (PV) under the cuff to be compressed so as to increase backpressure behind the compressed PV and subsequently increase the velocity of blood flow in the leg DV's when the EM is deflated. The EM can be inflated in a cycle including pulsed inflation, inflation hold and relaxation. The cycles can be repeated and adjusted to achieve a desired increase of blood flow/velocity in leg DV's.