Patents by Inventor Ramesh V. Nair

Ramesh V. Nair has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Promoter and plasmid system for genetic engineering
    Patent number: 8192959
    Abstract: This invention provides a series of low-copy number plasmids comprising restriction endonuclease recognition sites useful for cloning at least three different genes or operons, each flanked by a terminator sequence, the plasmids containing variants of glucose isomerase promoters for varying levels of protein expression. The materials and methods are useful for genetic engineering in microorganisms, especially where multiple genetic insertions are sought.
    Type: Grant
    Filed: April 22, 2003
    Date of Patent: June 5, 2012
    Assignees: Genencor International Inc, E I du Pont de Nemours and Company
    Inventors: Mark S. Payne, Stephen K. Picataggio, Amy K. Hsu, Ramesh V. Nair, Fernando Valle, Philippe Soucaille, Donald E. Trimbur
  • PROMOTER AND PLASMID SYSTEM FOR GENETIC ENGINEERING
    Publication number: 20110046014
    Abstract: This invention provides a series of low-copy number plasmids comprising restriction endonuclease recognition sites useful for cloning at least three different genes or operons, each flanked by a terminator sequence, the plasmids containing variants of glucose isomerase promoters for varying levels of protein expression. The materials and methods are useful for genetic engineering in microorganisms, especially where multiple genetic insertions are sought.
    Type: Application
    Filed: November 5, 2010
    Publication date: February 24, 2011
    Applicant: E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: MARK S. PAYNE, Stephen K. Picataggio, Amy Kuang-Hua Hsu, Ramesh V. Nair, Fernando Valle, Philippe Soucaille, Donald E. Trimbur
  • PROMOTER AND PLASMID SYSTEM FOR GENETIC ENGINEERING
    Publication number: 20090156430
    Abstract: This invention provides a series of low-copy number plasmids comprising restriction endonuclease recognition sites useful for cloning at least three different genes or operons, each flanked by a terminator sequence, the plasmids containing variants of glucose isomerase promoters for varying levels of protein expression. The materials and methods are useful for genetic engineering in microorganisms, especially where multiple genetic insertions are sought.
    Type: Application
    Filed: February 13, 2009
    Publication date: June 18, 2009
    Applicant: E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: Mark S. Payne, Stephen K. Picataggio, Amy Kuang-Hua Hsu, Ramesh V. Nair, Fernando Valle, Philippe Soucaille, Donald E. Trimbur
  • Promoter and plasmid system for genetic engineering
    Patent number: 7132527
    Abstract: This invention provides a series of low-copy number plasmids comprising restriction endonuclease recognition sites useful for cloning at least three different genes or operons, each flanked by a terminator sequence, the plasmids containing variants of glucose isomerase promoters for varying levels of protein expression. The materials and methods are useful for genetic engineering in microorganisms, especially where multiple genetic insertions are sought.
    Type: Grant
    Filed: December 18, 2003
    Date of Patent: November 7, 2006
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Mark S. Payne, Stephen K. Picataggio, Amy Kuang-Hsu, Ramesh V. Nair, Fernando Valle, Philippe Soucaille, Donald E. Trimbur
  • Transformed microorganisms and genes useful in the production of glycerol and 1,3-propanediol
    Patent number: 7005291
    Abstract: Recombinant organisms are provided comprising genes encoding a glycerol-3-phosphate dehydrogenase and/or a glycerol-3-phosphatase activity useful for the production of glycerol from a variety of carbon substrates. The organisms further contain disruptions in the endogenous genes encoding proteins having glycerol kinase and glycerol dehydrogenase activities.
    Type: Grant
    Filed: October 25, 2000
    Date of Patent: February 28, 2006
    Assignees: E. I. du Pont de Nemours and Company, Genencor International
    Inventors: Ramesh V. Nair, Mark S. Payne, Donald E. Trimbur, Fernando Valle
  • Promoter and plasmid system for genetic engineering
    Publication number: 20040235099
    Abstract: This invention provides a series of low-copy number plasmids comprising restriction endonuclease recognition sites useful for cloning at least three different genes or operons, each flanked by a terminator sequence, the plasmids containing variants of glucose isomerase promoters for varying levels of protein expression. The materials and methods are useful for genetic engineering in microorganisms, especially where multiple genetic insertions are sought.
    Type: Application
    Filed: December 18, 2003
    Publication date: November 25, 2004
    Inventors: Mark S. Payne, Stephen K. Picataggio, Amy Kuang-Hua Hsu, Ramesh V. Nair, Fernando Valle, Philippe Soucaille, Donald E. Trimbur
  • Method for the production of 1,3-propanediol by recombinant microorganisms
    Patent number: 6013494
    Abstract: Recombinant organisms are provided comprising genes encoding glycerol-3-phosphate dehydrogenase, glycerol-3-phosphatase, glycerol dehydratase and 1,3-propanediol oxidoreductase activites useful for the production of 1,3-propanediol from a variety of carbon substrates.
    Type: Grant
    Filed: November 12, 1997
    Date of Patent: January 11, 2000
    Assignees: E. I. du Pont de Nemours and Company, Genencor International
    Inventors: Charles E. Nakamura, Anthony A. Gatenby, Amy Kuang-Hua Hsu, Richard D. La Reau, Sharon L. Haynie, Maria Diaz-Torres, Donald E. Trimbur, Gregory M. Whited, Vasantha Nagarajan, Mark S. Payne, Stephen K. Picataggio, Ramesh V. Nair