Abstract: A method for detecting a nucleic acid in a plurality of samples, including a) providing analyte nucleic acids from samples in separate containers, the containers are in a subset array; b) amplifying acids by reaction using primers hybridized to the acids, forward and reverse primers of the primer pair both include an adaptor sequence, a sample identifier sequence and a binding sequence; c) combining the acids of step b) of containers of subsets to a container array; d) amplifying acids by a primer extension reaction using a pair of further primers hybridized to the acids of containers of step c), the further primers include a further forward and a further reverse primer, both including an identifier sequence and a hybridization sequence; e) determining the sequences of the acids of step d); f) assigning a determined sequence of a nucleic acid of interest of step e) to a sample

Abstract: A method of detecting Polycomb Repressive Complex (PRC) activity in a cell providing a cell with a DNA having a protein binding site and at least one reporter gene expression site is operatively connected to the protein binding site, and with a DNA containing a recombinant gene of a binding protein, the binding protein being capable of binding to the protein binding site, wherein the binding protein is fused to a member of the PRC, the method including the step of expressing the recombinant gene, letting the fused binding protein bind to the protein binding site and detecting at least one reporter gene expression.