Abstract: An accommodating intraocular lens (IOL) can be implanted either alone or as part of a two-part lens assembly. The IOL comprises an optic, a flexible membrane and a peripheral edge coupling the optic and the flexible membrane. The peripheral edge comprises an external circumferential surface having a height and a force transmitting area defined along a portion of the height of the external circumferential surface. A closed volume spaces apart the optic and the flexible membrane. The optic is axially displaced and the flexible membrane changes in curvature about a central axis when a radial compressive force is applied to the force transmitting area. A volume defined by the closed volume remains fixed when the optic is axially displaced and the flexible membrane changes in curvature and/or when the radial compressive force is applied to the force transmitting area.

Abstract: An explosive detection system for detecting explosive trace in a sample includes a detection unit, and a processing unit. The detection unit that receives a desorbed sample includes a first heater, a second heater, a first resistance temperature detector (RTD), a second RTD, and an amplifier. The first heater is exposed to the desorbed sample. The first heater and the second heater are supplied with specific voltage for three or more experiments. The first RTD and the second RTD measure changes in resistance due to heating of the first heater and the second heater to calculate voltages across the first RTD and the second RTD. The amplifier amplifies the voltages to calculate a differential voltage for each of the three or more experiments, and converts the differential voltage into a digital signal. The processing unit is configured to process the digital signal to detect explosive trace in the desorbed sample.

Abstract: A two-part accommodating intraocular lens (IOL) device for implantation in a capsular bag of a patient's eye. The IOL device includes a primary lens assembly and a power changing lens. The primary lens assembly includes a fixed lens and a peripherally disposed centration member. The centration member has a circumferential distal edge and a first coupling surface adjacent the circumferential distal edge. The power changing lens has an enclosed, fluid- or gel-filled lens cavity and haptic system disposed peripherally of the lens cavity. The haptic system has a peripheral engaging edge configured to contact the capsular bag and a second coupling surface. The first and second coupling surfaces are in sliding contact with one another to permit movement of the power changing lens relative to the primary lens assembly and also to maintain a spaced relationship between the fixed lens and the lens cavity during radial compression of the power changing lens.

Abstract: An intraocular device that includes a base member is provided. The device can be an accommodation intraocular lens device with the base member and a power changing lens. The base member comprises an annular haptic that surrounds a central cavity having an open end. The power changing lens is configured to fit within the central cavity. The haptic comprises one or more projections, e.g., tabs that hold another device in position. In the case of the accommodating intraocular lens device, the other device is the power changing lens. The base member and the power changing lens are maintained separate until assembly in the eye of the patient. During assembly, the base member is advanced into the capsular bag of a patient through a capsulorhexis and oriented such that the open end of the central cavity faces the cornea. Subsequently, the power changing lens is advanced into the central cavity through the capsulorhexis.

Abstract: An accommodating intraocular lens (IOL) can be implanted either alone or as part of a two-part lens assembly. The IOL comprises an optic, a flexible membrane and a peripheral edge coupling the optic and the flexible membrane. The peripheral edge comprises an external circumferential surface having a height and a force transmitting area defined along a portion of the height of the external circumferential surface. A closed volume spaces apart the optic and the flexible membrane. The optic is axially displaced and the flexible membrane changes in curvature about a central axis when a radial compressive force is applied to the force transmitting area. A volume defined by the closed volume remains fixed when the optic is axially displaced and the flexible membrane changes in curvature and/or when the radial compressive force is applied to the force transmitting area.

Abstract: Tunnel field effect devices and methods of fabricating tunnel field effect devices are described. In one embodiment, the semiconductor device includes a first drain region of a first conductivity type disposed in a first region of a substrate, a first source region of a second conductivity type disposed in the substrate, the second conductivity type being opposite the first conductivity type, a first channel region electrically coupled between the first source region and the first drain region, the first source region underlying a least a portion of the first channel region, and a first gate stack overlying the first channel region.

Abstract: A two-part accommodating intraocular lens (IOL) device for implantation in a capsular bag of a patient's eye. The IOL device includes a primary lens assembly and a power changing lens. The primary lens assembly includes a fixed lens and a peripherally disposed centration member. The centration member has a circumferential distal edge and a first coupling surface adjacent the circumferential distal edge. The power changing lens has an enclosed, fluid- or gel-filled lens cavity and haptic system disposed peripherally of the lens cavity. The haptic system has a peripheral engaging edge configured to contact the capsular bag and a second coupling surface. The first and second coupling surfaces are in sliding contact with one another to permit movement of the power changing lens relative to the primary lens assembly and also to maintain a spaced relationship between the fixed lens and the lens cavity during radial compression of the power changing lens.

Abstract: An accommodating intraocular lens (IOL) device adapted for implantation in the lens capsule of a subject's eye. The IOL device includes an anterior refractive optical element and a membrane coupled to the refractive optical element. The anterior refractive optical element and the membrane define an enclosed cavity configured to contain a fluid. At least a portion of the membrane is configured to contact a posterior area of the lens capsule adjoining the vitreous body of the subject's eye. The fluid contained in the enclosed cavity exerts a deforming or displacing force on the anterior refractive optical element in response to an anterior force exerted on the membrane by the vitreous body. The IOL device may further include a haptic system to position the anterior refractive optical element and also to engage the zonules and ciliary muscles to provide additional means for accommodation.

Abstract: A two-part accommodating intraocular lens (IOL) device for implantation in a capsular bag of a patient's eye. The IOL device includes a primary lens assembly and a power changing lens. The primary lens assembly includes a fixed lens and a peripherally disposed centration member. The centration member has a circumferential distal edge and a first coupling surface adjacent the circumferential distal edge. The power changing lens has an enclosed, fluid- or gel-filled lens cavity and haptic system disposed peripherally of the lens cavity. The haptic system has a peripheral engaging edge configured to contact the capsular bag and a second coupling surface. The first and second coupling surfaces are in sliding contact with one another to permit movement of the power changing lens relative to the primary lens assembly and also to maintain a spaced relationship between the fixed lens and the lens cavity during radial compression of the power changing lens.

Abstract: An accommodating intraocular lens (IOL) can be implanted either alone or as part of a two-part lens assembly. The IOL comprises an optic, a flexible membrane and a peripheral edge coupling the optic and the flexible membrane. The peripheral edge comprises an external circumferential surface having a height and a force transmitting area defined along a portion of the height of the external circumferential surface. A closed volume spaces apart the optic and the flexible membrane. The optic is axially displaced and the flexible membrane changes in curvature about a central axis when a radial compressive force is applied to the force transmitting area. A volume defined by the closed volume remains fixed when the optic is axially displaced and the flexible membrane changes in curvature and/or when the radial compressive force is applied to the force transmitting area.

Abstract: An accommodating intraocular lens (IOL) comprises an anterior lens, a posterior surface and an articulating member joining the anterior lens and the posterior surface to define an enclosed cavity. The articulating member comprises anterior and posterior arms coupling the anterior lens and the posterior surface, respectively. The articulating member further comprising a peripheral portion. A posterior flex region is disposed about the posterior arm and at a distance from the peripheral portion. The posterior flex region permits the flexible posterior surface to articulate relative to the posterior arm, to decrease the radius of curvature of the posterior surface as the peripheral portions on opposing sides of the IOL move toward one another in a first state and to increase the radius of curvature of the posterior surface as the peripheral portions on opposite sides of the IOL move away from one another in a second state.

Abstract: An accommodating intraocular lens device is provided. The accommodating intraocular lens device comprises a base assembly and a power lens. The base assembly comprises a first open end, a second end coupled to a base lens, and a haptic surrounding a central cavity. The haptic may comprise an outer periphery, an inner surface and a height between a first edge and a second edge. The power lens is configured to fit within the central cavity. The power lens may comprise a first side, a second side, a peripheral edge coupling the first and second sides, and a closed cavity configured to house a fluid. The first side of the power lens may be positioned at a predetermined distance from the first edge of the haptic.

Abstract: A method for adjusting the refractive power of a fluid-filled intraocular lens implanted into a patient's eye. The method comprises selecting a pattern to cause a flattening of the intraocular lens or an increase in curvature of the intraocular lens, and ablating the pattern, onto either an optical element of the intraocular lens or a flexible element of the intraocular lens, to alter either one or both of a refractive power and an amplitude of accommodation of the intraocular lens. The ablating occurs while the intraocular lens remains implanted in the patient's eye. The ablating maintains the integrity of a fluid-filled interior cavity defined between the optical element and the flexible element, but causes the flattening of the intraocular lens or the increase in curvature of the intraocular lens.

Abstract: An accommodating intraocular lens (IOL) can be implanted either alone or as part of a two-part lens assembly. The IOL comprises an optic, a flexible membrane and a peripheral edge coupling the optic and the flexible membrane. The peripheral edge comprises an external circumferential surface having a height and a force transmitting area defined along a portion of the height of the external circumferential surface. A closed volume spaces apart the optic and the flexible membrane. The optic is axially displaced and the flexible membrane changes in curvature about a central axis when a radial compressive force is applied to the force transmitting area. A volume defined by the closed volume remains fixed when the optic is axially displaced and the flexible membrane changes in curvature and/or when the radial compressive force is applied to the force transmitting area.

Abstract: An explosive detection system for detecting explosive trace in a sample includes a detection unit, and a processing unit. The detection unit that receives a desorbed sample includes a first heater, a second heater, a first resistance temperature detector (RTD), a second RTD, and an amplifier. The first heater is exposed to the desorbed sample. The first heater and the second heater are supplied with specific voltage for three or more experiments. The first RTD and the second RTD measure changes in resistance due to heating of the first heater and the second heater to calculate voltages across the first RTD and the second RTD. The amplifier amplifies the voltages to calculate a differential voltage for each of the three or more experiments, and converts the differential voltage into a digital signal. The processing unit is configured to process the digital signal to detect explosive trace in the desorbed sample.

Abstract: A polymer based photo-detector has photoresponsivity in Ultraviolet, Visible, Near and Mid Infrared regions. The photo-detector comprises a single layer of polyvinyl alcohol (PVA) as a photoactive layer; with no additional buffer layer for accepting Ultraviolet, Visible and Infrared radiation as well as no buffer layer to block charge carrier injection. The PVA layer's photoresponsivity is extended from Ultraviolet to Near Infrared by changing its nano-morphology on a low thermal device structure. The primarily photo-generated charge carriers diffuse through the amorphous part of the polymer layer and split into charge carriers on the electrodes or by the charge traps in the layer. The charge carrier generation is in the picosecond range; thus the exciton and Polaron drift diffusion cause electrical conduction of the polymer layer under Ultraviolet illumination.

Abstract: In an embodiment of the invention, a semiconductor device includes a first region having a first doping type, a channel region having the first doping type disposed in the first region, and a retrograde well having a second doping type. The second doping type is opposite to the first doping type. The retrograde well has a shallower layer with a first peak doping and a deeper layer with a second peak doping higher than the first peak doping. The device further includes a drain region having the second doping type over the retrograde well. An extended drain region is disposed in the retrograde well, and couples the channel region with the drain region. An isolation region is disposed between a gate overlap region of the extended drain region and the drain region. A length of the drain region is greater than a depth of the isolation region.

Abstract: Tunnel field effect devices and methods of fabricating tunnel field effect devices are described. In one embodiment, the semiconductor device includes a first drain region of a first conductivity type disposed in a first region of a substrate, a first source region of a second conductivity type disposed in the substrate, the second conductivity type being opposite the first conductivity type, a first channel region electrically coupled between the first source region and the first drain region, the first source region underlying a least a portion of the first channel region, and a first gate stack overlying the first channel region.

Abstract: Tunnel field effect devices and methods of fabricating tunnel field effect devices are described. In one embodiment, the semiconductor device includes a first drain region of a first conductivity type disposed in a first region of a substrate, a first source region of a second conductivity type disposed in the substrate, the second conductivity type being opposite the first conductivity type, a first channel region electrically coupled between the first source region and the first drain region, the first source region underlying a least a portion of the first channel region, and a first gate stack overlying the first channel region.

Abstract: An intraocular lens (IOL) device comprising a first lens, a second lens and a circumferential haptic. The first lens comprises a pair of opposing and deformable surfaces and a cavity defined therebetween. The first lens has a first lens diameter. The second lens has a second lens diameter. The circumferential haptic has an outer peripheral edge and couples the first lens and the second lens. A main IOL cavity is defined by the circumferential haptic, the first lens and the second lens. The IOL device is resiliently biased to an unaccommodated state, characterized by the IOL device having a first diameter d1 in the absence of radial compressive forces exerted on the outer peripheral edge. The IOL device actuates to an accommodated state being characterized by a second diameter d2 in response to radial compressive forces exerted on the outer peripheral edge, wherein d1>d2.