Patents by Inventor Rami A. AL-HORANI

Rami A. AL-HORANI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHENYL UNSATURATED KETONES AS HUMAN FACTOR XIIIA INHIBITORS FOR TREATMENT OF THROMBOEMBOLIC DISEASES
    Publication number: 20240010602
    Abstract: The present disclosure is directed to compounds having Formula (I) and their enantiomers, wherein the definitions of R, Y1, Y2, W, X, Z, and n are provided in the disclosure. The disclosure is also directed to pharmaceutical compositions of the disclosed compounds, as well as their use for treatment of thrombosis and related conditions and complications.
    Type: Application
    Filed: July 6, 2023
    Publication date: January 11, 2024
    Inventor: Rami A. AL-HORANI
  • Allosteric modulators of factor XIa as anticoagulant agents
    Patent number: 9758459
    Abstract: Compounds which allosterically modulate and/or inhibit factor XIa activity are provided, as are methods of their use. These compounds include i) sulfated gallolyl glucosides, ii) sulfated quinazolinones, and iii) sulfated inositol analogs. The compounds used as anticoagulant agents.
    Type: Grant
    Filed: November 12, 2013
    Date of Patent: September 12, 2017
    Assignee: Virginia Commonwealth University
    Inventors: Umesh R. Desai, Rajesh Karuturi, Akul Mehta, Rami A. Al-Horani
  • ALLOSTERIC MODULATORS OF FACTOR XIa AS ANTICOAGULANT AGENTS
    Publication number: 20160311842
    Abstract: Compounds which allosterically modulate and/or inhibit factor XIa activity are provided, as are methods of their use. These compounds include i) sulfated gallolyl glucosides, ii) sulfated quinazolinones, and iii) sulfated inositol analogs. The compounds used as anticoagulant agents.
    Type: Application
    Filed: November 12, 2013
    Publication date: October 27, 2016
    Inventors: Umesh R. DESAI, Rajesh KARUTURI, Akul MEHTA, Rami A. AL-HORANI