Abstract: A system and method for reducing blockchain transaction delay are disclosed. The system consists of a trusted coin wallet framework that implements a trusted execution environment to initiate currency transactions between two clients. The trusted coin wallet framework includes an API proxy and a trusted shadow wallet. The method used by the trusted coin wallet framework involves interaction between the trusted shadow wallet and a peer trusted wallet owned by the other client, via the API proxy, from within the trusted execution environment. During these operations, the blockchain infrastructure is independently validating the transaction.

Abstract: The present disclosure generally relates, in certain embodiments, to light-based treatments. In some case, a subject having or at risk for a condition such as insomnia can be treated, e.g., with light, such as green light. Other conditions include sleep disorders such as sleep apnea and other indications. In some cases, the light that is administered to the subject may be green light, or the light may have a characteristic wavelength only in a wavelength range between 510 nm and 550 nm with a bandwidth no larger than 20 nm full-width-half-maximum. Other embodiments described herein are generally directed to systems for treating such conditions, kits for treating such conditions, or the like.

Abstract: The present invention relates to methods for selecting a headache patient responsive to treatment with an anti-CGRP antibody and to methods for reducing headache frequency in the selected patient comprising administering an anti-CGRP antibody.

Abstract: The present invention relates to methods for selecting a headache patient responsive to treatment with an anti-CGRP antibody and to methods for reducing headache frequency in the selected patient comprising administering an anti-CGRP antibody.

Abstract: Provided is an invention based on methods to treat or prevent headaches with injectable compositions comprising botulinum toxin that may be administered using an injection paradigm that provides botulinum toxin at one or more locations of neuronal activity associated with EEG detectable brain cortical electrical activity to a subject suffering from such malady. Co-therapuetics therewith are also disclosed.

Abstract: Methods for treating seizures and for inhibiting progression of a focal seizure to a generalized seizure by administering extracranially a Clostridial derivative are described.

Abstract: Apparatus and methods for producing narrow-band radiation in the green region of the visible spectrum are described. The narrow-band radiation may be used to aid subjects experiencing photophobia. In some cases, subjects may experience a reduction in pain (e.g., migraine photophobia) when using the narrow-band radiation.

Abstract: A system and method for reducing blockchain transaction delay are disclosed. The system consists of a trusted coin wallet framework that implements a trusted execution environment to initiate currency transactions between two clients. The trusted coin wallet framework includes an API proxy and a trusted shadow wallet. The method used by the trusted coin wallet framework involves interaction between the trusted shadow wallet and a peer trusted wallet owned by the other client, via the API proxy, from within the trusted execution environment. During these operations, the blockchain infrastructure is independently validating the transaction.

Abstract: A system and method for reducing blockchain transaction delay are disclosed. The system consists of a trusted coin wallet framework that implements a trusted execution environment to initiate currency transactions between two clients. The trusted coin wallet framework includes an API proxy and a trusted shadow wallet. The method used by the trusted coin wallet framework involves interaction between the trusted shadow wallet and a peer trusted wallet owned by the other client, via the API proxy, from within the trusted execution environment. During these operations, the blockchain infrastructure is independently validating the transaction.

Abstract: Methods for the treatment and prevention of diseases and disorders associated with cortical spreading depression by administering a CGRP antagonist, a Clostridial derivative or combination thereof are described.

Abstract: The present invention is related to compositions and methods for treating or reducing the likelihood of a migraine, reducing the severity of migraine, reducing the frequency of migraines, reducing the duration of migraine, and ameliorating the symptoms of a migraine. The methods and compositions of the present invention may also be used to treat or prevent condition characterized by increased cardiovascular risk or endothelial dysfunction and musculoskeletal symptoms.

Abstract: Methods for treating seizures and for inhibiting progression of a focal seizure to a generalized seizure by administering extracranially a Clostridial derivative are described.

Abstract: The present invention relates to methods for selecting a headache patient responsive to treatment with an anti-CGRP antibody and to methods for reducing headache frequency in the selected patient comprising administering an anti-CGRP antibody.

Abstract: Apparatus and methods for producing narrow-band radiation in the green region of the visible spectrum are described. The narrow-band radiation may be used to aid subjects experiencing photophobia. In some cases, subjects may experience a reduction in pain (e.g., migraine photophobia) when using the narrow-band radiation.

Abstract: The present invention relates to methods for selecting a headache patient responsive to treatment with an anti-CGRP antibody and to methods for reducing headache frequency in the selected patient comprising administering an anti-CGRP antibody.

Abstract: Apparatus and methods for producing narrow-band radiation in the green region of the visible spectrum are described. The narrow-band radiation may be used to aid subjects experiencing photophobia. In some cases, subjects may experience a reduction in pain (e.g., migraine photophobia) when using the narrow-band radiation.

Abstract: A system and method for reducing blockchain transaction delay are disclosed. The system consists of a trusted coin wallet framework that implements a trusted execution environment to initiate currency transactions between two clients. The trusted coin wallet framework includes an API proxy and a trusted shadow wallet. The method used by the trusted coin wallet framework involves interaction between the trusted shadow wallet and a peer trusted wallet owned by the other client, via the API proxy, from within the trusted execution environment. During these operations, the blockchain infrastructure is independently validating the transaction.

Abstract: The present invention relates to methods for selecting a headache patient responsive to treatment with an anti-CGRP antibody and to methods for reducing headache frequency in the selected patient comprising administering an anti-CGRP antibody.

Abstract: Disclosed herein are methods of preventing incidence of a migrainous or non-migrainous post-ictal headache, and/or at least one secondary symptom associated with a migrainous post-ictal headache in a subject comprising administering to the subject a monoclonal antibody that modulates the CGRP pathway. Compositions for use in the disclosed methods are also provided.

Abstract: Apparatus and methods for producing narrow-band radiation in the green region of the visible spectrum are described. The narrow-band radiation may be used to aid subjects experiencing photophobia. In some cases, subjects may experience a reduction in pain (e.g., migraine photophobia) when using the narrow-band radiation.