Patents by Inventor Ramkumar K. Mandalam

Ramkumar K. Mandalam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human lineage committed cell composition with enhanced proliferative potential, biological effector function, or both; methods for obtaining same; and their uses
    Patent number: 6835566
    Abstract: A method for obtaining lineage committed human cells imbued with enhanced proliferative potential, biological function, or both, comprising culturing lineage committed human cells under physiologically acceptable liquid culture conditions, where the liquid culture medium is replaced at a rate and for a time sufficient to obtain the human lineage committed cells imbued with enhanced proliferative potential, biological function, or both; and isolating the cultured cells.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: December 28, 2004
    Assignee: Aastrom Biosciences, Inc.
    Inventors: Alan K. Smith, Douglas M. Smith, Ramkumar K. Mandalam
  • Human linkeage committed cell composition with enhanced proliferative potential, biological effector function, or both; methods for obtaining same; and their uses
    Publication number: 20040185557
    Abstract: A method for obtaining lineage committed human cells imbued with enhanced proliferative potential, biological function, or both, comprising culturing lineage committed human cells under physiologically acceptable liquid culture conditions, where the liquid culture medium is replaced at a rate and for a time sufficient to obtain the human lineage committed cells imbued with enhanced proliferative potential, biological function, or both; and isolating the cultured cells.
    Type: Application
    Filed: April 2, 2004
    Publication date: September 23, 2004
    Applicant: AASTROM BIOSCIENCES, INC.
    Inventors: Alan K. Smith, Douglas M. Smith, Ramkumar K. Mandalam
  • Human lineage committed cell composition with enhanced proliferative potential, biological effector function, or both; methods for obtaining same; and their uses
    Publication number: 20040062755
    Abstract: A method for obtaining lineage committed human cells imbued with enhanced proliferative potential, biological function, or both, comprising culturing lineage committed human cells under physiologically acceptable liquid culture conditions, where the liquid culture medium is replaced at a rate and for a time sufficient to obtain the human lineage committed cells imbued with enhanced proliferative potential, biological function, or both; and isolating the cultured cells.
    Type: Application
    Filed: September 24, 2003
    Publication date: April 1, 2004
    Applicant: AASTROM BIOSCIENCES, INC.
    Inventors: Alan K. Smith, Douglas M. Smith, Ramkumar K. Mandalam
  • HUMAN LINEAGE COMMITTED CELL COMPOSITION WITH ENHANCED PROLIFERATIVE POTENTIAL, BIOLOGICAL EFFECTOR FUNCTION, OR BOTH; METHODS FOR OBTAINING SAME; AND THEIR USES
    Publication number: 20020034819
    Abstract: A method for obtaining lineage committed human cells imbued with enhanced proliferative potential, biological function, or both, comprising culturing lineage committed human cells under physiologically acceptable liquid culture conditions, where the liquid culture medium is replaced at a rate and for a time sufficient to obtain the human lineage committed cells imbued with enhanced proliferative potential, biological function, or both; and isolating the cultured cells.
    Type: Application
    Filed: February 23, 1998
    Publication date: March 21, 2002
    Inventors: ALAN K. SMITH, DOUGLAS M. SMITH, RAMKUMAR K. MANDALAM
  • Human lineage committed cell composition with enhanced proliferative potential, biological effector function, or both; methods for obtaining same; and their uses
    Publication number: 20020031498
    Abstract: A method for obtaining lineage committed human cells imbued with enhanced proliferative potential, biological function, or both, comprising culturing lineage committed human cells under physiologically acceptable liquid culture conditions, where the liquid culture medium is replaced at a rate and for a time sufficient to obtain the human lineage committed cells imbued with enhanced proliferative potential, biological function, or both; and isolating the cultured cells.
    Type: Application
    Filed: June 29, 2001
    Publication date: March 14, 2002
    Applicant: AASTROM BIOSCIENCES, INC.
    Inventors: Alan K. Smith, Douglas M. Smith, Ramkumar K. Mandalam