Abstract: A multiple description (MD) joint source-channel (JSC) encoder in accordance with the invention encodes n components of an audio signal for transmission over m channels of a communication medium, where n and m may take on any desired values. In an illustrative embodiment, the encoder combines a multiple description transform coder with elements of a perceptual audio coder (PAC). The encoder is configured to select one or more transform parameters for a multiple description transform, based on a characteristic of the audio signal to be encoded. For example, the transform parameters may be selected such that the resulting transformed coefficients have a variance distribution of a type expected by a subsequent entropy coding operation. The components of the audio signal may be quantized coefficients separated into a number of factor bands, and the transform parameter for a given factor band may be set to a value determined based on a transform parameter from at least one other factor band, e.g.