Abstract: The disclosure provides nonsteroidal anti-inflammatory compositions and methods of use thereof. Specifically, the disclosure provides cell-free or substantially cell-free regenerative nonsteroidal anti-inflammatory compositions derived from placenta and/or from MSC cells isolated therefrom, methods for producing said compositions, and uses thereof to treat chronic and acute inflammatory conditions and diseases.

Abstract: The disclosure provides nonsteroidal anti-inflammatory compositions and methods of use thereof. Specifically, the disclosure provides cell-free or substantially cell-free regenerative nonsteroidal anti-inflammatory compositions derived from placenta and/or from MSC cells isolated therefrom, methods for producing said compositions, and uses thereof to treat chronic and acute inflammatory conditions and diseases.

Abstract: The invention provides methods for the validation of donor immune-regulatory cells. The validation method includes a combination of assays to determine the capability of immune-regulatory cells to immune-regulate adaptive and innate immune system components.

Abstract: The invention provides a method of producing and using extracellular vesicles (ECVs) derived from activated stromal cells for the treatment of certain disease and conditions. Specifically, ECVs derived from preactivated mesenchymal cells are effective in reducing cancer cell growth and metastasis as well as inducing tolerogenesis in immature dendritic cells. Additionally, ECVs derived from umbilical cord blood may be useful for immunosuppression and reduction of inflammation.

Abstract: Disclosed is a system and method for aiding the sterility of a laboratory by suspending items using magnetic force to a laboratory object, such as a cap or a lid, wherein such cap may be suspended on a rack or stand comprising an arm extending horizontally. The system allows for suspension of items rather than placing them on surfaces, which may lead to contamination. The system may further prevent mixing of lids by increasing organizational capability by magnetic suspension of the caps or lids. The disclosed system supports a wide variety of scenarios for laboratory settings and related products and services.

Abstract: Disclosed is a system and method for aiding the sterility of a laboratory by suspending items using magnetic force to a laboratory object, such as a cap or a lid, wherein such cap may be suspended on a rack or stand comprising an arm extending horizontally. The system allows for suspension of items rather than placing them on surfaces, which may lead to contamination. The system may further prevent mixing of lids by increasing organizational capability by magnetic suspension of the caps or lids. The disclosed system supports a wide variety of scenarios for laboratory settings and related products and services.

Abstract: Disclosed is an improved composition characterized in containing a combination of melatonin and 5-HTP in a nasal administration for the rapid treatment of insomnia, anxiety, and related disorders in mammals, including humans. The present invention relates also to a pharmaceutical composition comprising 5-HTP and melatonin which utilizes the known effects of two substances to provide sleep improvement, relaxation, and reduced anxiety via rapid delivery of the combination, via nasal administration, for short-term alleviation of sleep disorder and anxiety-related symptoms. The combined effects of 5-HTP and melatonin in the present invention provide a short-term increase in blood plasma levels of melatonin while simultaneously increasing the production of serotonin for purposes of achieving natural melatonin biosynthesis in combination with the increased melatonin content in blood plasma.