Abstract: A tissue fastening device includes a body including a plurality of sidewalls defining a channel, an anvil having a proximal end and a distal end and pivotally coupled to the body and the anvil moves between an open position and a closed position, and a locking mechanism to lock the anvil in the closed position.

Abstract: A system for treating tissue includes a clip assembly including a pair of clip arms, proximal ends of which are slidably received within a channel of a capsule to be moved between a tissue receiving configuration, in which distal ends of the clip arms are separated from one another, and a tissue clipping configuration, in which the distal ends are moved toward one another. The system also includes an applicator including a catheter and a control member extending therethrough. The control member configured to be connected to the clip arms to move the clip assembly between the tissue receiving and tissue clipping configurations. The system also includes a coupler attached to one of a proximal end of the capsule of the clip assembly and a distal end of the catheter, and configured to releasably couple the capsule and the catheter to one another.

Abstract: A system for treating tissue includes a clip assembly having a pair of clip arms. Proximal ends of the clip arms engage a distal portion of a central member slidably received within a channel of a capsule to be moved between an open configuration and a closed configuration. The central member includes the distal portion and a proximal portion connected to one another via a releasable connection which releases when subject to a force exceeding a predetermined threshold level. The system also includes an applicator releasably coupled to the clip assembly. The applicator includes an outer sleeve through which a control member extends. A distal end of the control member engages a cavity of the proximal portion to move the central member relative to the capsule. A lumen of the outer sleeve is sized and shaped to slidably receive the capsule therein.

Abstract: The present disclosure pertains to medical devices. More particularly, the present disclosure pertains to tissue clip devices and related systems and methods. In an embodiment, a tissue clip may include a grasper including jaws at a first end, and a spring portion at a second end, and a longitudinal axis extending along a length of the grasper from the first end to the second end, wherein the spring portion is configured to bias the jaws toward each other. A wedge may be slidably disposed between the jaws such that an apex of the wedge is oriented toward the spring portion. A filament may be coupled to the wedge at a first end of the filament and may extend through a channel of the spring portion of the grasper to a second end of the filament.

Abstract: A system for treating tissue includes a clip assembly including a pair of clip arms, proximal ends of the clip arms slidably received within a channel of a capsule to be moved between a tissue receiving configuration and a tissue clipping configuration, an applicator including a catheter and a control member extending therethrough, a distal end of the control member configured to be connected to the clip arms to move the clip assembly between the tissue receiving and tissue clipping configurations, and a coupler releasably coupled to proximal ends of the clip arms and configured to be coupled to the distal end of the control member, the coupler configured to yield when a proximal force exerted on the coupler via the control member exceeds a first predetermined threshold value to disengage the clip arms to deploy the clip assembly.

Abstract: According to one aspect, a tissue fastening device may include a handle assembly including at least two actuators. The tissue fastening device may also include a first body extending distally from the handle assembly and defining a longitudinal axis. The tissue fastening device may also include a fastening device coupled to a distal end of the first body. The fastening device may include a longitudinal body including a channel, a cartridge configured to include a plurality of fasteners, a longitudinal channel configured to receive a device for cutting tissue, an anvil rotatable relative to the cartridge, and a fastener actuator. The fastener actuator may be coupled to one actuator of the at least two actuators and configured to move proximally relative to the cartridge to deploy the plurality of fasteners from the cartridge.

Abstract: A system for treating tissue includes a clip assembly including a pair of clip arms, proximal ends of the clip arms slidably received within a channel of a capsule to be moved between a tissue receiving configuration and a tissue clipping configuration, and an applicator releasably coupleable to the clip assembly to move the clip assembly between the tissue receiving configuration and the tissue clipping configuration, the applicator including a control member having a plurality of nodes extending therealong, each node having a cross-sectional are larger than a cross-sectional area of a remaining portion of the control member and configured to be coupled to the proximal end of the clip arms, a distal-most one of the nodes severable from a next immediately proximal one of the nodes, when a force exerted thereon exceeds a predetermined threshold value, to release the clip assembly from the applicator.

Abstract: A system for treating tissue includes an applicator having a bushing and a control member and a clip assembly having a capsule with a channel extending therethrough. The channel includes proximal and distal portions. The distal portion extends distally from the proximal portion and flaring outward in a single plane to form opposing flared sections. The assembly also includes clip arms include proximal ends slidably received within the channel to move the arms between tissue receiving and tissue clipping configurations. The assembly further includes a yoke including a distal portion connected to the arms and a proximal portion configured to be connected to the member so that longitudinal movement of the member relative to the capsule moves the arms between the tissue receiving and clipping configurations. The yoke is positioned in the capsule so that the yoke is deformable in the plane in which the capsule flares outward.

Abstract: A system for treating tissue includes an applicator and a clip assembly. The applicator includes a catheter extending longitudinally and a lumen extending therethrough, a control member extending through the lumen of the catheter. The assembly is releasably coupleable to a distal end of the applicator. The assembly includes a pair of clip arms, proximal ends of which are slidably received within a channel of a capsule, a pair of opposing coupling elements extending proximally from the proximal ends of the arms to be fixed over the distal end of the member so that the arms are movable relative to the capsule via a longitudinal motion of the member between a tissue receiving configuration, in which distal ends of the arms are separated from one another, and a tissue clipping configuration, in which distal ends of the arms are moved toward one another.

Abstract: A system for treating tissue includes an applicator having a bushing and a control member and a clip assembly having a capsule with a channel extending therethrough. The channel includes proximal and distal portions. The distal portion extends distally from the proximal portion and flaring outward in a single plane to form opposing flared sections. The assembly also includes clip arms include proximal ends slidably received within the channel to move the arms between tissue receiving and tissue clipping configurations. The assembly further includes a yoke including a distal portion connected to the arms and a proximal portion configured to be connected to the member so that longitudinal movement of the member relative to the capsule moves the arms between the tissue receiving and clipping configurations. The yoke is positioned in the capsule so that the yoke is deformable in the plane in which the capsule flares outward.

Abstract: A medical device includes a shaft including a lumen configured to direct a flow of fluid through the shaft and an electrode. A proximal end of the electrode and a distal end of the shaft form a coupling configured to releasably couple the proximal end of the electrode with the distal end of the shaft. When the proximal end of the electrode is coupled to the distal end of the shaft, fluid delivered through the lumen is emitted from the electrode.

Abstract: According to one aspect, an instrument may include a sheath having a distal end. The instrument also may include a fluid cannula at the distal end of the sheath. The instrument also may include a cutting electrode at the distal end of the sheath. At least one of: (i) an exterior surface of the fluid cannula, and (ii) a cutting electrode surface that faces the exterior surface, is longitudinally slidable along the other of the exterior surface and the cutting electrode surface during movement of at least one of the cutting electrode and the fluid cannula relative to the other of the cutting electrode and the fluid cannula.

Abstract: A medical device includes a shaft including a central lumen configured to direct a flow of fluid through the shaft, and an electrode positioned at a distal portion of the shaft. The electrode includes an electrode lumen in fluid communication with the central lumen, and the electrode lumen is configured to receive the flow of fluid from the central lumen. The electrode also includes one or more channels angled relative to the electrode lumen, and the one or more channels are in fluid communication with the electrode lumen to receive the flow of fluid from the electrode lumen. The one or more channels are configured to divert the flow of fluid from the electrode lumen toward one or more outlets laterally offset from the electrode lumen.

Abstract: A steering assembly includes a movable anchor. Movement of the anchor in a first direction is restricted. A first linkage is coupled to the anchor and a second linkage it rotatably coupled to the first linkage. The second linkage is configured to couple to a contactor. A drive mechanism moves the second linkage relative to the first linkage. At least one of moving the second linkage and moving the anchor maneuvers the contactor to a desired position.

Abstract: The present disclosure pertains to medical devices. More particularly, the present disclosure pertains to tissue retraction devices and related delivery systems and methods.

Abstract: A system for treating tissue includes a clip assembly having a pair of clip arms. Proximal ends of the clip arms engage a distal portion of a central member slidably received within a channel of a capsule to be moved between an open configuration and a closed configuration. The central member includes the distal portion and a proximal portion connected to one another via a releasable connection which releases when subject to a force exceeding a predetermined threshold level. The system also includes an applicator releasably coupled to the clip assembly. The applicator includes an outer sleeve through which a control member extends. A distal end of the control member engages a cavity of the proximal portion to move the central member relative to the capsule. A lumen of the outer sleeve is sized and shaped to slidably receive the capsule therein.

Abstract: A system for treating tissue includes a clip assembly including a pair of clip arms, proximal ends of which are slidably received within a channel of a capsule to be moved between a tissue receiving configuration, in which distal ends of the clip arms are separated from one another, and a tissue clipping configuration, in which the distal ends are moved toward one another. The system also includes an applicator including a catheter and a control member extending therethrough. The control member configured to be connected to the clip arms to move the clip assembly between the tissue receiving and tissue clipping configurations. The system also includes a coupler attached to one of a proximal end of the capsule of the clip assembly and a distal end of the catheter, and configured to releasably couple the capsule and the catheter to one another.

Abstract: A system for treating tissue includes an applicator and a clip assembly. The applicator includes a catheter extending longitudinally and a lumen extending therethrough, a control member extending through the lumen of the catheter. The assembly is releasably coupleable to a distal end of the applicator. The assembly includes a pair of clip arms, proximal ends of which are slidably received within a channel of a capsule, a pair of opposing coupling elements extending proximally from the proximal ends of the arms to be fixed over the distal end of the member so that the arms are movable relative to the capsule via a longitudinal motion of the member between a tissue receiving configuration, in which distal ends of the arms are separated from one another, and a tissue clipping configuration, in which distal ends of the arms are moved toward one another.

Abstract: A system for treating tissue includes an applicator having a bushing and a control member and a clip assembly having a capsule with a channel extending therethrough. The channel includes proximal and distal portions. The distal portion extends distally from the proximal portion and flaring outward in a single plane to form opposing flared sections. The assembly also includes clip arms include proximal ends slidably received within the channel to move the arms between tissue receiving and tissue clipping configurations. The assembly further includes a yoke including a distal portion connected to the arms and a proximal portion configured to be connected to the member so that longitudinal movement of the member relative to the capsule moves the arms between the tissue receiving and clipping configurations. The yoke is positioned in the capsule so that the yoke is deformable in the plane in which the capsule flares outward.

Abstract: A system for treating tissue includes a clip assembly including a pair of clip arms, proximal ends of the clip arms slidably received within a channel of a capsule to be moved between a tissue receiving configuration and a tissue clipping configuration, an applicator including a catheter and a control member extending therethrough, a distal end of the control member configured to be connected to the clip arms to move the clip assembly between the tissue receiving and tissue clipping configurations, and a coupler releasably coupled to proximal ends of the clip arms and configured to be coupled to the distal end of the control member, the coupler configured to yield when a proximal force exerted on the coupler via the control member exceeds a first predetermined threshold value to disengage the clip arms to deploy the clip assembly.