Abstract: Topical ophthalmic solution compositions of gatifloxacin are disclosed. The compositions do not contain disodium edetate or any other metal chelating agent.

Abstract: Topical solution compositions of brimonidine tartrate are disclosed. The solution compositions lack an oxidative preservative.

Abstract: A method for recovering oil in a reservoir by generating chemical microexplosions in the reservoir. The invention treats the hydrocarbon-bearing reservoir by decomposing in situ at least one imidazolidone derivative, thereby generating heat, shock, and CO2. A preferred method comprises the steps of depositing an imidazolidone derivative into the formation and depositing an acid into the formation to cause the imidazolidone derivative to decompose and generate heat and gas.

Abstract: Disclosed are preservative systems useful in aqueous pharmaceutical compositions containing an active agent and a cyclodextrin. The preservative systems comprise boric acid and one or more compounds selected from the group consisting of C.sub.16 benzalkonium halide compounds, polymeric quatemary ammonium compounds, and quatemary ammonium alkylene glycol phospholipid derivatives of the following structure ##STR1## where a+b=3; R.sup.1 is C.sub.8 -C.sub.22 alkyl or alkene; X is NH, O, or CH.sub.2 ; R.sup.2 is C.sub.2 -C.sub.6 alkyl; each R.sup.3 is independently C.sub.1 -C.sub.12 alkyl or alkene; and Y is nothing or C.sub.1 -C.sub.6 alkyl or alkene; and pharmaceutically acceptable salts thereof.

Abstract: A lubricating oil composition having improved antiwear, antioxidancy and fuel economy properties which comprises a hydroisomerized wax basestock and an alkoxylated amine salt of a dihydrocarbyldithiophosphoric acid of the formula ##STR1## where R.sup.1 and R.sup.2 are each independently hydrocarbyl groups having from 3 to 30 carbon atoms, R.sup.3 is a hydrocarbyl group of 2 to 22 carbon atoms, x and y are each independently integers from 1 to 15 with the proviso that the sum of x+y is from 2 to 20.

Abstract: This invention relates to the use of ketanserinol as an ophthalmic therapeutic agent to reduce intraocular pressure and its method of use for treating glaucoma by systemic administration of ketanserinol, it salts, esters or prodrugs to a patient or more particularly, topically administering ketanserinol and salts thereof to the eye of a patient.

Abstract: A multistep process is disclosed for the manufacture of synthetic lubricants from the C.sub.8 to C.sub.24 linear olefin components of below liquid fuel value petroleum distillate fractions derived via the high temperature thermal cracking of petroleum residua. Such feeds contain major amounts of 1-n-olefins, n-paraffins and greater than 0.1% concentration of sulfur mostly in the form aromatic, thiophene type sulfur compounds.In the first step of the present process such feeds are enriched in the straight chain aliphatic hydrocarbon components by one or more separation processes, preferably via urea adduction or by crystallization. In the second step, the olefin components are oligomerized to sulfur containing C.sub.30 to C.sub.60 polyolefins, preferably in the presence of BF.sub.3 complex catalysts. In the third step, the polyolefins are hydrogenated to novel isoparaffin lubricants in the presence of sulfur resistant catalysts, preferably transition metal sulfides.

Abstract: This invention relates to a process for the extraction of bitumen from tar sands which comprises contacting the tar sand in an extraction zone with a paraffinic hydrocarbon solvent having from 5 to 9 carbon atoms at a ratio of from 2 to 10 parts solvent per part of bitumen present in the tar sand, maintaining the asphaltene fraction of said tar sands in suspension, separating a major portion of said solvent which contains a major amount of the bitumen dissolved therein along with the suspended asphaltene fraction from the extracted sand, passing the extracted sand along with a minor portion of said solvent and a minor amount of bitumen into a water contacting zone and therein contacting said extracted sand with sufficient water at a temperature of at least 100.degree. F.

Abstract: Methanol is prepared from a feed gas containing carbon oxides and hydrogen by passing the feed gas through a catalyst bed in contact with an inert hydrocarbon liquid of the paraffinic or cycloparaffinic type under reaction conditions such that the equivalent methanol concentration in the liquid medium (corrected to 250.degree. C and 1000 psig) does not exceed 1.0 wt. %. The use of paraffinics and cycloparaffinics has significant advantages in reactor productivity over the use of other inert hydrocarbon liquids such as aromatics.