Patents by Inventor Ramona J. Petrovan

Ramona J. Petrovan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified factor VIIa
    Patent number: 7173000
    Abstract: A modified factor VIIa is provided. The modified factor has increased amidolytic activity in the absence of T.F. and a higher affinity for T.F. when compared to the native factor VIIa but does not have substantially altered proteolytic activity when bound to T.F. Nucleic acid molecules that encode the factor, expression vectors that contain the nucleic acid molecules, cells that contain the nucleic acid molecules, and cells transformed with the expression vector are also provided. In a preferred embodiment, the modified factor is a human factor VIIa.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: February 6, 2007
    Assignee: The Scripps Research Institute
    Inventors: Wolfram Ruf, Ramona J. Petrovan
  • Modified factor viia
    Publication number: 20040033566
    Abstract: A modified factor VIIa is provided. The modified factor has increased amidolytic activity in the absence of T.F. and a higher affinity for T.F. when compared to the native factor VIIa but does not have substantially altered proteolytic activity when bound to T.F. Nucleic acid molecules that encode the factor, expression vectors that contain the nucleic acid molecules, cells that contain the nucleic acid molecules, and cells transformed with the expression vector are also provided. In a preferred embodiment, the modified factor is a human factor VIIa.
    Type: Application
    Filed: May 5, 2003
    Publication date: February 19, 2004
    Inventors: Wolfram Ruf, Ramona J Petrovan