Patents by Inventor Rampyari Walia

Rampyari Walia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified Luciferases And Uses Thereof
    Publication number: 20170335293
    Abstract: The present invention encompasses modified luciferases, methods for making modified luciferases, and assays utilizing modified luciferases. Modified luciferases of the invention show increased activity over wildtype luciferases and also show increased stability of signal. The present invention also encompasses multiplex assays utilizing multiple luciferases with different emission spectra.
    Type: Application
    Filed: June 29, 2017
    Publication date: November 23, 2017
    Inventor: Rampyari Walia
  • Modified luciferases and uses thereof
    Patent number: 9732328
    Abstract: The present invention encompasses modified luciferases, methods for making modified luciferases, and assays utilizing modified luciferases. Modified luciferases of the invention show increased activity over wildtype luciferases and also show increased stability of signal. The present invention also encompasses multiplex assays utilizing multiple luciferases with different emission spectra.
    Type: Grant
    Filed: January 20, 2016
    Date of Patent: August 15, 2017
    Assignee: Targeting Systems
    Inventor: Rampyari Walia
  • Modified Luciferases And Uses Thereof
    Publication number: 20160264944
    Abstract: The present invention encompasses modified luciferases, methods for making modified luciferases, and assays utilizing modified luciferases. Modified luciferases of the invention show increased activity over wildtype luciferases and also show increased stability of signal. The present invention also encompasses multiplex assays utilizing multiple luciferases with different emission spectra.
    Type: Application
    Filed: January 20, 2016
    Publication date: September 15, 2016
    Inventor: Rampyari Walia
  • Multiplex assays with multiple luciferases reporters and uses thereof
    Patent number: 9353401
    Abstract: The present invention encompasses modified luciferases, methods for making modified luciferases, and assays utilizing modified luciferases. Modified luciferases of the invention show increased activity over wildtype luciferases and also show increased stability of signal. The present invention also encompasses multiplex assays utilizing multiple luciferases reporters with different emission spectra and different substrates for simultaneous luciferase measurements.
    Type: Grant
    Filed: August 27, 2010
    Date of Patent: May 31, 2016
    Assignee: Targeting Systems
    Inventor: Rampyari Walia
  • LUCIFERASES AND USES THEREOF
    Publication number: 20120156705
    Abstract: The present invention encompasses modified luciferases, methods for making modified luciferases, and assays utilizing modified luciferases. Modified luciferases of the invention show increased activity over wildtype luciferases and also show increased stability of signal. The present invention also encompasses multiplex assays utilizing multiple luciferases with different emission spectra.
    Type: Application
    Filed: August 27, 2010
    Publication date: June 21, 2012
    Applicant: Targeting Systems
    Inventor: Rampyari Walia
  • DE-DIFFERENTIATION OF HUMAN CELLS
    Publication number: 20110033931
    Abstract: Methods of de-differentiating somatic cells to an embryonic stem cell state comprising direct delivery of a protein into the somatic cell, wherein the protein effects de-differentiation of the somatic cell to an embryonic stem cell phenotype.
    Type: Application
    Filed: November 26, 2008
    Publication date: February 10, 2011
    Applicant: CHILDREN'S HOSPITAL OF ORANGE COUNTY
    Inventors: Philip Schwartz, Rampyari Walia
  • Enhancement of nucleic acid transfer by coupling virus to nucleic acid via lipids
    Patent number: 5635380
    Abstract: This invention provides a method of enhancing the delivery of a nucleic acid into a cell, wherein a complex is formed comprising the nucleic acid, a cationic liposome, and a replication-deficient adenovirus, and the complex is administered to the cell to thereby enhance delivery of the nucleic acid into the cell. The method can be used to deliver the nucleic acid into a cell in a subject by administering the above complex into the subject.
    Type: Grant
    Filed: January 18, 1994
    Date of Patent: June 3, 1997
    Assignee: Vanderbilt University
    Inventors: Allen J. Naftilan, Rampyari Walia