Patents by Inventor Ramy Lidor

Ramy Lidor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRYSTALLINE FORM OF ASPACYTARABINE
    Publication number: 20230331762
    Abstract: The present invention relates to a novel crystalline polymorph of (¾)-2-amino-4-(0-42R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyptetrahydrofuran-2-yl)-2-oxo-1,2- dihydropyrimidin-4-yl)amino)-4-oxobutanoic acid (also known as BST-236, Astarabine® or aspacytarabine), processes of preparation thereof, and uses thereof for the treatment of neoplastic diseases.
    Type: Application
    Filed: September 20, 2021
    Publication date: October 19, 2023
    Applicant: Biosight Ltd.
    Inventors: Ramy LIDOR-HADAS, Margarita SHUMILOV, Shoshanna TESSLER
  • Process for preparing pridopidine
    Patent number: 10047049
    Abstract: This invention provides a pridopidine base in a solid form, a method of preparing the solid pridopidine base, and a composition comprising the pridopidine base including a pharmaceutical composition.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: August 14, 2018
    Assignee: TEVA PHARMACEUTICALS INTERNATIONAL GMBH
    Inventors: Offir Barel, Ramy Lidor-Hadas, Ronen Gottesfeld, Orel Yosef Mizrahi, Anders Olof Ingemar Bergh, Ba-Vu Nguyen
  • PROCESS FOR PREPARING PRIDOPIDINE
    Publication number: 20170022158
    Abstract: This invention provides a pridopidine base in a solid form, a method of preparing the solid pridopidine base, and a composition comprising the pridopidine base including a pharmaceutical composition.
    Type: Application
    Filed: July 22, 2016
    Publication date: January 26, 2017
    Applicant: Teva Pharmaceuticals International GmbH
    Inventors: Offir Barel, Ramy Lidor-Hadas, Ronen Gottesfeld, Orel Yosef Mizrahi, Anders Olof Ingemar Bergh, Ba-Vu Nguyen
  • R(+)-N-formyl-propargyl-aminoindan
    Patent number: 9346746
    Abstract: The subject invention provides R(+)-N-formyl-propargyl-aminoindan and a composition containing N-propargyl-1(R)-aminoindan or a pharmaceutically acceptable salt thereof, and a compound of R(+)-N-formyl-propargyl-aminoindan.
    Type: Grant
    Filed: October 9, 2012
    Date of Patent: May 24, 2016
    Assignee: TEVA PHARMACEUTICAL INDUSTRIES, LTD.
    Inventors: Muhammad Safadi, Anton Frenkel, Michal Keisar, Danit Licht, Eliezer Bahar, Ramy Lidor-Hadas, Marina Zholkovsky, Rachel Cohen
  • R(+)-N-methyl-propargyl-aminoindan
    Patent number: 9339469
    Abstract: The subject invention provides R(+)-N-methyl-propargyl-aminoindan or a pharmaceutically acceptable salt thereof and a composition containing R(+)-N-propargyl-1(R)-aminoindan or a pharmaceutically acceptable salt thereof, and a compound of R(+)-N-methyl-propargyl-aminoindan or a salt thereof.
    Type: Grant
    Filed: October 9, 2012
    Date of Patent: May 17, 2016
    Assignee: TEVA PHARMACEUTICAL INDUSTRIES, LTD.
    Inventors: Muhammad Safadi, Anton Frenkel, Michal Keisar, Danit Licht, Eliezer Bahar, Ramy Lidor-Hadas, Marina Zholkovsky, Rachel Cohen
  • 3-KETO-N-PROPARGYL-1-AMINOINDAN
    Publication number: 20150045445
    Abstract: The subject invention provides a pharmaceutical composition containing N-propargyl-1(R)-aminoindan or a pharmaceutically acceptable salt thereof, and a compound of 3-keto-N-propargyl-1-aminoindan or a salt thereof.
    Type: Application
    Filed: October 23, 2014
    Publication date: February 12, 2015
    Applicant: TEVA PHARMACEUTICAL INDUSTRIES, LTD.
    Inventors: Anton Frenkel, Ramy Lidor-Hadas, Eliezer Bahar
  • 3-KETO-N-PROPARGYL-1-AMINOINDAN
    Publication number: 20110152381
    Abstract: The subject invention provides a pharmaceutical composition containing N-propargyl-1(R)-aminoindan or a pharmaceutically acceptable salt thereof, and a compound of 3-keto-N-propargyl-1-aminoindan or a salt thereof.
    Type: Application
    Filed: December 21, 2010
    Publication date: June 23, 2011
    Inventors: Anton Frenkel, Ramy Lidor-Hadas, Eliezer Bahar
  • Rasagiline formulations and processes for their preparation
    Patent number: 7619117
    Abstract: The subject invention provides a pharmaceutical composition comprising N-propargyl-1(R)-aminoindan mesylate; a pharmaceutically acceptable carrier; and greater than 0.7 ppm but less than 30 ppm in total of a compound having the structure: and any salts of the compound.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: November 17, 2009
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Ramy Lidor-Hadas, Eliezer Bahar
  • Rasagiline formulations and processes for their preparation
    Patent number: 7598420
    Abstract: The subject invention provides a pharmaceutical composition comprising N-propargyl-1(R)-aminoindan mesylate; a pharmaceutically acceptable carrier; and greater than 0.7 ppm but less than 30 ppm in total of a compound having the structure: and any salts of the compound.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: October 6, 2009
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Jeffrey Sterling, David Lerner, Harel Rosen, Leonid Bronov, Dalia Medini-Green, Berta Iosefzon, Tirtsah Berger-Peskin, Ramy Lidor-Hadas, Eliezer Bahar
  • Rasagiline formulations and processes for their preparation
    Patent number: 7572834
    Abstract: The subject invention provides a pharmaceutical composition comprising N-propargyl-1(R)-aminoindan mesylate; a pharmaceutically acceptable carrier; and greater than 0.7 ppm but less than 30 ppm in total of a compound having the structure: and any salts of the compound.
    Type: Grant
    Filed: December 5, 2006
    Date of Patent: August 11, 2009
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Jeffrey Sterling, David Lerner, Harel Rosen, Leonid Bronov, Dalia Medini-Green, Berta Iosefzon, Tirtsah Berger-Peskin, Ramy Lidor-Hadas, Eliezer Bahar
  • Methods for isolating propargylated aminoindans
    Patent number: 7491847
    Abstract: A process for isolating from a reaction mixture a salt of a mono-propargylated aminoindan, a process for isolating from a reaction mixture a crystalline diastereomeric salt of a mono-propargylated aminoindan, and a process for isolating from a reaction mixture a salt of enantiomerically pure N-propargyl-1-aminoindan or a salt of enantiomerically pure 6-(N-methyl, N-ethyl-carbamoyloxy)-N?-propargyl-1-aminoindan. The corresponding products are also disclosed.
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: February 17, 2009
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Anton Frenkel, Ramy Lidor-Hadas, Eduard Gurevich, Gsan Attili
  • Crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
    Patent number: 7488750
    Abstract: The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
    Type: Grant
    Filed: October 24, 2005
    Date of Patent: February 10, 2009
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Judith Aronhime, Ramy Lidor-Hadas, Valerie Niddam, Revital Lifshitz, Shlomit Wizel
  • Crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
    Patent number: 7468444
    Abstract: The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
    Type: Grant
    Filed: October 24, 2005
    Date of Patent: December 23, 2008
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Judith Aronhime, Ramy Lidor-Hadas, Valerie Niddam, Revital Lifshitz, Shlomit Wizel
  • Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel process for preparing other forms
    Publication number: 20080214650
    Abstract: The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
    Type: Application
    Filed: October 23, 2007
    Publication date: September 4, 2008
    Inventors: Judith Aronhime, Ramy Lidor-Hadas, Valerie Niddam, Revital Lifshitz, Shlomit Wizel
  • Crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
    Patent number: 7342120
    Abstract: The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
    Type: Grant
    Filed: October 24, 2005
    Date of Patent: March 11, 2008
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Judith Aronhime, Ramy Lidor-Hadas, Valerie Niddam, Revital Lifshitz, Shlomit Wizel
  • Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
    Publication number: 20070265456
    Abstract: The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin. Also provided is atorvastatin hemi-calcium Form VIII that is stable against the formation of atorvastatin hemi-calcium is atorvastatin calcium epoxy dihydroxy (AED).
    Type: Application
    Filed: May 9, 2006
    Publication date: November 15, 2007
    Inventors: Judith Aronhime, Ramy Lidor-Hadas, Valerie Niddam-Hildesheim, Shlomit Wizel, Revital Lifshitz-Liron, Michael Pinchasov
  • Methods for isolating propargylated aminoindans
    Publication number: 20070112217
    Abstract: Disclosed is a process for isolating from a reaction mixture a salt of a mono-propargylated aminoindan having the structure wherein R1 is H, hydroxyl, alkoxy or wherein Y is O or S; R2 and R3 is each, independently, C1-8 alkyl, C6-12 aryl, C6-12 aralkyl, each optionally halo substituted, or hydrogen; where the reaction mixture further comprises a solvent, a primary aminoindan having the structure wherein R1 is defined as above, and a tertiary aminoindan having the structure the process comprising d) adding an acid to the reaction mixture; e) crystallizing the mono-propargylated aminoindan under conditions suitable for the formation of a crystalline salt of the mono-propargylated aminoindan; and f) recovering the crystalline salt of the mono-propargylated aminoindan, wherein the process is performed without addition of an organic solvent. Also disclosed are the crystalline diastereomeric salts produced by the process and pharmaceutical compositions containing the salts.
    Type: Application
    Filed: November 15, 2006
    Publication date: May 17, 2007
    Inventors: Anton Frenkel, Ramy Lidor-Hadas, Eduard Gurevich, Gsan Attili
  • Crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
    Patent number: 7144916
    Abstract: The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
    Type: Grant
    Filed: November 19, 2004
    Date of Patent: December 5, 2006
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Judith Aronhime, Ramy Lidor-Hadas, Valerie Niddam, Revital Lifshitz, Shlomit Wizel
  • Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
    Publication number: 20060106231
    Abstract: The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
    Type: Application
    Filed: October 24, 2005
    Publication date: May 18, 2006
    Inventors: Judith Aronhime, Ramy Lidor-Hadas, Valerie Niddam-Hildesheim, Revital Lifshitz-Liron, Shlomit Wizel
  • Novel crystal forms of atorvastatin hemi-calcium and processes for their preparation as well as novel processes for preparing other forms
    Publication number: 20060106232
    Abstract: The present invention provides novel forms of atorvastatin designated Forms VI, VIII, IX, X, XI and XII and novel processes for their preparation as well as processes for preparing atorvastatin Forms I, II, IV, V and amorphous atorvastatin.
    Type: Application
    Filed: October 24, 2005
    Publication date: May 18, 2006
    Inventors: Judith Aronhime, Ramy Lidor-Hadas, Valerie Niddam-Hildesheim, Revital Lifshitz-Liron, Shlomit Wizel