Abstract: Embodiments of the present invention provide for assessing the state of an 82Rb elution system. In certain embodiments, a system begins an assessment that comprises an elution, and a metric may be measured. This metric may be a concentration of 82Rb, 82Sr, or 85Sr in a fluid that is eluted from the generator, the volume of the fluid that is eluted from the generator, or the pressure of the fluid flowing through at least one portion of the system. If the assessment is completed, an output may be generated on a user interface that recommends a course of action, or no course of action, based on a result of the assessment. Should the assessment not complete successfully because it is interrupted, a 82Sr/82Rb generator of the system may be halted so as to prevent a user from performing an end-run around these quality control mechanisms of the 82Rb elution system.

Abstract: Embodiments of the present invention provide for assessing the state of an 82Rb elution system. In certain embodiments, a system begins an assessment that comprises an elution, and a metric may be measured. This metric may be a concentration of 82Rb, 82Sr, or 85Sr in a fluid that is eluted from the generator, the volume of the fluid that is eluted from the generator, or the pressure of the fluid flowing through at least one portion of the system. If the assessment is completed, an output may be generated on a user interface that recommends a course of action, or no course of action, based on a result of the assessment. Should the assessment not complete successfully because it is interrupted, a 82Sr/82Rb generator of the system may be halted so as to prevent a user from performing an end-run around these quality control mechanisms of the 82Rb elution system.

Abstract: Provided are 82Sr/82Rb elution systems that accept patient weight as a input function in order to determine an optimal quantity of radioactive rubidium-82 for delivery to a patient pursuant to an imaging scan. Also disclosed are systems that deliver a saline flush to remove residual 82Rb from the system downstream of the generator, and preferably deliver the removed residual 82Rb to the patient. Other disclosed systems measure the total volume of saline that flows through a 82Sr/82Rb generator, a total volume of saline that flows through the generator and through a bypass line, or a total volume of saline received by a waste reservoir, in order to monitor system components so that optimal system functioning is assured.

Abstract: Embodiments of the present invention provide for assessing the state of an 82Rb elution system. In certain embodiments, a system begins an assessment that comprises an elution, and a metric may be measured. This metric may be a concentration of 82Rb, 82Sr, or 85Sr in a fluid that is eluted from the generator, the volume of the fluid that is eluted from the generator, or the pressure of the fluid flowing through at least one portion of the system. If the assessment is completed, an output may be generated on a user interface that recommends a course of action, or no course of action, based on a result of the assessment. Should the assessment not complete successfully because it is interrupted, a 82Sr/82Rb generator of the system may be halted so as to prevent a user from performing an end-run around these quality control mechanisms of the 82Rb elution system.

Abstract: The present invention describes methods and techniques to improve scintigraphic images obtained by using nuclear medicine techniques for diagnostic analysis. The present invention describes a method and technique to up-sample and down-sample nuclear medicine images that models photon counts and noise characteristics of an image at its target resolution.

Abstract: Embodiments of the present invention provide for assessing the state of an 82Rb elution system. In certain embodiments, a system begins an assessment that comprises an elution, and a metric may be measured. This metric may be a concentration of 82Rb, 82Sr, or 85Sr in a fluid that is eluted from the generator, the volume of the fluid that is eluted from the generator, or the pressure of the fluid flowing through at least one portion of the system. If the assessment is completed, an output may be generated on a user interface that recommends a course of action, or no course of action, based on a result of the assessment. Should the assessment not complete successfully because it is interrupted, a 82Sr/82Rb generator of the system may be halted so as to prevent a user from performing an end-run around these quality control mechanisms of the 82Rb elution system.

Abstract: Embodiments of the present invention provide for assessing the state of an 82Rb elution system. In certain embodiments, a system begins an assessment that comprises an elution, and a metric may be measured. This metric may be a concentration of 82Rb, 82Sr, or 85Sr in a fluid that is eluted from the generator, the volume of the fluid that is eluted from the generator, or the pressure of the fluid flowing through at least one portion of the system. If the assessment is completed, an output may be generated on a user interface that recommends a course of action, or no course of action, based on a result of the assessment. Should the assessment not complete successfully because it is interrupted, a 82Sr/82Rb generator of the system may be halted so as to prevent a user from performing an end-run around these quality control mechanisms of the 82Rb elution system.

Abstract: Provided are 82Sr/82Rb elution systems that accept patient weight as a input function in order to determine an optimal quantity of radioactive rubidium-82 for delivery to a patient pursuant to an imaging scan. Also disclosed are systems that deliver a saline flush to remove residual 82Rb from the system downstream of the generator, and preferably deliver the removed residual 82Rb to the patient. Other disclosed systems measure the total volume of saline that flows through a 82Sr/82Rb generator, a total volume of saline that flows through the generator and through a bypass line, or a total volume of saline received by a waste reservoir, in order to monitor system components so that optimal system functioning is assured.

Abstract: Embodiments of the present invention provide for assessing the state of an 82Rb elution system. In certain embodiments, a system begins an assessment that comprises an elution, and a metric may be measured. This metric may be a concentration of 82Rb, 82Sr, or 85Sr in a fluid that is eluted from the generator, the volume of the fluid that is eluted from the generator, or the pressure of the fluid flowing through at least one portion of the system. If the assessment is completed, an output may be generated on a user interface that recommends a course of action, or no course of action, based on a result of the assessment. Should the assessment not complete successfully because it is interrupted, a 82Sr/82Rb generator of the system may be halted so as to prevent a user from performing an end-run around these quality control mechanisms of the 82Rb elution system.

Abstract: Embodiments of the present invention provide for assessing the state of an 82Rb elution system. In certain embodiments, a system begins an assessment that comprises an elution, and a metric may be measured. This metric may be a concentration of 82Rb, 82Sr, or 85Sr in a fluid that is eluted from the generator, the volume of the fluid that is eluted from the generator, or the pressure of the fluid flowing through at least one portion of the system. If the assessment is completed, an output may be generated on a user interface that recommends a course of action, or no course of action, based on a result of the assessment. Should the assessment not complete successfully because it is interrupted, a 82Sr/82Rb generator of the system may be halted so as to prevent a user from performing an end-run around these quality control mechanisms of the 82Rb elution system.

Abstract: Provided are 82Sr/82Rb elution systems that accept patient weight as a input function in order to determine an optimal quantity of radioactive rubidium-82 for delivery to a patient pursuant to an imaging scan. Also disclosed are systems that deliver a saline flush to remove residual 82Rb from the system downstream of the generator, and preferably deliver the removed residual 82Rb to the patient. Other disclosed systems measure the total volume of saline that flows through a 82Sr/82Rb generator, a total volume of saline that flows through the generator and through a bypass line, or a total volume of saline received by a waste reservoir, in order to monitor system components so that optimal system functioning is assured.

Abstract: Embodiments of the present invention provide for assessing the state of an 82Rb elution system. In certain embodiments, a system begins an assessment that comprises an elution, and a metric may be measured. This metric may be a concentration of 82Rb, 82Sr, or 85Sr in a fluid that is eluted from the generator, the volume of the fluid that is eluted from the generator, or the pressure of the fluid flowing through at least one portion of the system. If the assessment is completed, an output may be generated on a user interface that recommends a course of action, or no course of action, based on a result of the assessment. Should the assessment not complete successfully because it is interrupted, a 82Sr/82Rb generator of the system may be halted so as to prevent a user from performing an end-run around these quality control mechanisms of the 82Rb elution system.

Abstract: A method of controlling an 82Sr/82Rb elution system having a generator valve for proportioning a flow of saline solution between an 82Sr/82Rb generator and a bypass line coupled to an outlet of the generator such that saline solution traversing the bypass line will merge with eluted saline solution emerging from the generator to provide an active saline solution. During each elution run, a plurality of successive concentration parameter values are obtained at predetermined intervals. Each concentration parameter value is indicative of a respective instantaneous activity concentration of the active saline solution. Respective error values between each concentration parameter value and a target activity concentration value of the elution run are computed. Error data based on a plurality of the computed error values is accumulated. Between successive elution runs, at least one performance parameter of the elution system is adjusted based on the accumulated error data.

Abstract: A method of controlling an 82Sr/82Rb elution system having a generator valve for proportioning a flow of saline solution between an 82Sr/82Rb generator and a bypass line coupled to an outlet of the generator such that saline solution traversing the bypass line will merge with eluted saline solution emerging from the generator to provide an active saline solution. During each elution run, a plurality of successive concentration parameter values are obtained at predetermined intervals. Each concentration parameter value is indicative of a respective instantaneous activity concentration of the active saline solution. Respective error values between each concentration parameter value and a target activity concentration value of the elution run are computed. Error data based on a plurality of the computed error values is accumulated. Between successive elution runs, at least one performance parameter of the elution system is adjusted based on the accumulated error data.