Patents by Inventor Ran Yu

Ran Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240140944
    Abstract: The present invention relates to a novel naphthyridinone derivative compound, a pharmaceutically acceptable salt thereof, a hydrate thereof, or a stereoisomer thereof, which are each relevant to a compound for inhibiting ENPP1, a composition for inhibiting ENPP1, and a method for inhibiting ENPP1.
    Type: Application
    Filed: December 29, 2021
    Publication date: May 2, 2024
    Applicant: TXINNO BIOSCIENCE INC.
    Inventors: Seo Jung Han, Chan Sun Park, Sung Joon Kim, Jae Eun Cheong, Jung Hwan Choi, Ali Imran, Sun Woo Lee, Yong Yea Park, Ah Ran Yu, Sun Young Park
  • Patent number: 11961637
    Abstract: This disclosure relates to a stretchable composite electrode and a fabricating method thereof, and particularly relates to a stretchable composite electrode including a silver nanowire layer and a flexible polymer film and a fabricating method thereof.
    Type: Grant
    Filed: December 7, 2022
    Date of Patent: April 16, 2024
    Assignee: TPK ADVANCED SOLUTIONS INC.
    Inventors: Wei Sheng Chen, Ching Mao Huang, Jia Hui Zhou, Huan Ran Yu, Shu Xiong Wang, Chin Hui Lee
  • Publication number: 20240116882
    Abstract: The present invention relates to a novel benzotriazole derivative compound, a tautomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof, or a stereoisomer thereof, which are related to a compound for inhibiting ENPP1, a composition for inhibiting ENPP1, and a method for inhibiting ENPP1.
    Type: Application
    Filed: January 28, 2022
    Publication date: April 11, 2024
    Applicant: TXINNO BIOSCIENCE INC.
    Inventors: Chan Sun Park, Sung Joon Kim, Ali Imran, Yoo Jin Na, So Ra Paik, Jung Hwan Choi, Sun Woo Lee, Yong Yea Park, Ah Ran Yu, Sun Young Park
  • Patent number: 11609403
    Abstract: An optical module includes a first bearer and a second bearer. The first bearer includes a first bearing portion and an inclined plane, the first bearing portion is configured to carry a first optical element, and the inclined plane is disposed on a peripheral edge of a first end surface of the first bearing portion. The second bearer includes a second bearing portion and a protruding portion, the second bearing portion is configured to carry a second optical element, a second end surface of the second bearing portion faces the first end surface, and the protruding portion extends from the second end surface to the first bearing portion and is configured to contact the inclined plane. When the protruding portion contacts the inclined plane, the inclined plane does not expose the protruding portion in a direction from the first bearing portion to the second bearing portion.
    Type: Grant
    Filed: February 13, 2020
    Date of Patent: March 21, 2023
    Assignees: SINTAI OPTICAL (SHENZHEN) CO., LTD., ASIA OPTICAL CO., INC.
    Inventors: Chaeg-Ran Yu, Chiao-Sen Hsu, Keng-Hui Lin
  • Publication number: 20230026810
    Abstract: The disclosure discloses a high-frequency transmission LCP film and preparation method thereof. The preparation method comprises the following steps: (1) separately performing acetylation on monomers to obtain acetylated monomers; (2) performing high-temperature polymerization on the acetylated monomers, phenolic resin, acetic anhydride and zinc acetate, and performing pulverization to obtain liquid crystal copolyester; (3) ball milling the liquid crystal copolyester, an inorganic filler, a silane coupling agent and a glass fiber and mixing to obtain a mixture; and melt-plasticizing the mixture to form a film after cooling, performing longitudinal and transverse synchronous stretching, then winding and slitting the film to obtain a high-frequency transmission LCP film.
    Type: Application
    Filed: September 6, 2021
    Publication date: January 26, 2023
    Inventors: Dongbao ZHANG, Ran YU, Liang XU
  • Publication number: 20200310075
    Abstract: An optical module includes a first bearer and a second bearer. The first bearer includes a first bearing portion and an inclined plane, the first bearing portion is configured to carry a first optical element, and the inclined plane is disposed on a peripheral edge of a first end surface of the first bearing portion. The second bearer includes a second bearing portion and a protruding portion, the second bearing portion is configured to carry a second optical element, a second end surface of the second bearing portion faces the first end surface, and the protruding portion extends from the second end surface to the first bearing portion and is configured to contact the inclined plane. When the protruding portion contacts the inclined plane, the inclined plane does not expose the protruding portion in a direction from the first bearing portion to the second bearing portion.
    Type: Application
    Filed: February 13, 2020
    Publication date: October 1, 2020
    Inventors: Chaeg-Ran Yu, Chiao-Sen Hsu, Keng-Hui Lin
  • Publication number: 20190022590
    Abstract: The present invention provides a device for separating and purifying the collagen Type 2 in chicken bones, comprising a liquid fluid container, a raw liquid container, a membrane separation tank, a mixing tube, two high pressure metering motors, a precooler, two preheaters, a temperature controller, two one-way valves, two inlet control valves and two outlet control valves. The liquid extract of defatted chicken bones discharged from the raw liquid container and the liquid CO2 discharged from the liquid fluid container can be mixed uniformly in the mixing tube, and then fed into the membrane separation tank. The membrane separation tank produces small-molecular-weight peptides and large-molecular-weight collagen Type 2 harmlessly and efficiently.
    Type: Application
    Filed: October 5, 2017
    Publication date: January 24, 2019
    Inventors: Zer-Ran Yu, Hui-Chen Kuo, Be-Jen Wang, Po-Wen Yu, Hui-Chen Chung, Shu-Mei Lin, Kuo-Chuan Chen, Tsai-Jen Hung
  • Patent number: 9567365
    Abstract: The present invention provides a method of separating estrogen from placenta, which uses supercritical fluid technique to load the placenta powder of human body or sheep, pig, deer and other animals into an extraction tank. Under the operating conditions of preset pressure and temperature, supercritical solvent is added into the extraction tank to extract estrogen from placenta, so as to acquire de-estrogen placenta powder and placenta extract liquor. Under the same condition, the de-estrogen placenta extract liquor and supercritical solvent are added by a preset volume flow ratio into an adsorption tank. The estrogen in the placenta extract liquor is adsorbed by the adsorption tank to obtain de-estrogen placenta extract. It is then eluted with ethanol solution by gradient proportion to obtain purified natural estrogen.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: February 14, 2017
    Assignees: SUPER WELL BIOTECHNOLOGY CORPORATION, ULTRA-MICRORIGIN BIOMEDICAL TECHNOLOGY CO., LTD.
    Inventors: Zer-Ran Yu, Be-Jen Wang, Shu-Mei Lin, Hua-Ching Lin, Ming-Hsi Chuang, Chu-Ting Liu, Chiu-Ying Peng, Lin-Hsiang Chuang
  • Publication number: 20160159847
    Abstract: The present invention provides a method of separating estrogen from placenta, which uses supercritical fluid technique to load the placenta powder of human body or sheep, pig, deer and other animals into an extraction tank. Under the operating conditions of preset pressure and temperature, supercritical solvent is added into the extraction tank to extract estrogen from placenta, so as to acquire de-estrogen placenta powder and placenta extract liquor. Under the same condition, the de-estrogen placenta extract liquor and supercritical solvent are added by a preset volume flow ratio into an adsorption tank. The estrogen in the placenta extract liquor is adsorbed by the adsorption tank to obtain de-estrogen placenta extract. It is then eluted with ethanol solution by gradient proportion to obtain purified natural estrogen.
    Type: Application
    Filed: February 9, 2016
    Publication date: June 9, 2016
    Inventors: Zer-Ran YU, Be-Jen WANG, Shu-Mei LIN, Hua-Ching LIN, Ming-Hsi CHUANG, Chu-Ting LIU, Chiu-Ying PENG, Lin-Hsiang CHUANG
  • Publication number: 20160122213
    Abstract: Methods of controlling a nitrification reaction in a biological nitrogen removal reactor to favor partial nitrification of ammonia to nitrite instead of complete oxidation of ammonia to nitrate are disclosed. In some embodiments, the methods include the following: maintaining a pH in the reactor within a range that promotes growth of ammonia oxidizing bacteria; maintaining a concentration of dissolved oxygen in the reactor within a range that limits the ammonia oxidizing bacteria from completing nitrification; selecting an operational solids retention time within a range suitable for maintaining increasing concentrations of the ammonia oxidizing bacteria in the reactor while reducing concentrations of nitrite oxidizing bacteria in the reactor; and increasing a concentration of free ammonia in the reactor thereby inhibiting growth of the nitrite oxidizing bacteria in the reactor.
    Type: Application
    Filed: January 11, 2016
    Publication date: May 5, 2016
    Inventors: Kartik Chandran, Ran Yu, Joon Ho Ahn
  • Publication number: 20160074773
    Abstract: The present invention provides a method to separate and purify functional ingredients in placenta using supercritical fluid technology, where, placenta extract liquid and supercritical CO2 solvent are guided into a fractionation tank constantly in a preset velocity at a preset temperature and pressure to extract peptides, proteins and other functional ingredients. And then, the solution is conveyed through the three fractionation tanks at a preset temperature and depressurized gradually to separate, fractionate and purify the content of placenta peptide and protein, so as to obtain the high purity of peptides, proteins, active factors and other functional ingredients.
    Type: Application
    Filed: May 1, 2015
    Publication date: March 17, 2016
    Inventors: Zer-Ran YU, Be-Jen WANG, Shu-Mei LIN, Hua-Ching LIN, Ming-Hsi CHUANG, Chu-Ting LIU, I-Lung YU, Chiu-Ying PENG, Lin-Hsiang CHUANG
  • Publication number: 20160051591
    Abstract: The present invention provides a method for the separation of placenta functional ingredients. By using the supercritical fluid technology, the placenta powder is placed inside an extraction tank, under the predetermined pressure and temperature; the supercritical CO2 solvent is flown into the adsorption tank, in order to deodorize the fishy smell of the placenta powder, and extract the oil of the placenta powder. Under the same operating conditions as mentioned above, the deodorized and extracted placenta powder and supercritical CO2/ethanol solvents are flown into an adsorption tank at the predetermined volumetric flow rate ratio to adsorb the estrogen of placenta powder to get the estrogen-removed placenta peptide extracts. Afterwards, supercritical CO2/ethanol solvents are separated by rapid decompression to get the functional ingredients of placenta powder.
    Type: Application
    Filed: May 1, 2015
    Publication date: February 25, 2016
    Inventors: Zer-Ran YU, Be-Jen WANG, Tsao-Chen WEI, Hua-Ching LIN, Ming-Hsi CHUANG, Chu-Ting LIU, I-Lung YU, Chiu-Ying PENG, Lin-Hsiang CHUANG
  • Patent number: 9266920
    Abstract: The present invention provides a preparation method of deglycosylated ginsenosides, which uses the supercritical fluid technology to conduct the deglycosylation of ginsenosides extract in supercritical solvent under preset pressure and temperature conditions. Under the same operational conditions, the deglycosylated ginsenosides extract and solvent at supercritical state are input into an adsorption tank at the preset volume flow rate ratio for the adsorption of ginsenosides. Then, the adsorbed ginsenosides are applied with gradient eluent by using the ethanol solution. Finally, the pressure is lowered for the separation and purification of ginsenosides to get the deglycosylated ginsenosides of high concentration.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: February 23, 2016
    Inventors: Zer-Ran Yu, Shuen-An Kang
  • Patent number: 9233864
    Abstract: Methods of controlling a nitrification reaction in a biological nitrogen removal reactor to favor partial nitrification of ammonia to nitrite instead of complete oxidation of ammonia to nitrate are disclosed. In some embodiments, the methods include the following: maintaining a pH in the reactor within a range that promotes growth of ammonia oxidizing bacteria; maintaining a concentration of dissolved oxygen in the reactor within a range that limits the ammonia oxidizing bacteria from completing nitrification; selecting an operational solids retention time within a range suitable for maintaining increasing concentrations of the ammonia oxidizing bacteria in the reactor while reducing concentrations of nitrite oxidizing bacteria in the reactor; and increasing a concentration of free ammonia in the reactor thereby inhibiting growth of the nitrite oxidizing bacteria in the reactor.
    Type: Grant
    Filed: November 19, 2013
    Date of Patent: January 12, 2016
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Kartik Chandran, Ran Yu, Joon Ho Ahn
  • Publication number: 20150274769
    Abstract: The present invention provides a method of separating estrogen from placenta, which uses supercritical fluid technique to load the placenta powder of human body or sheep, pig, deer and other animals into an extraction tank. Under the operating conditions of preset pressure and temperature, supercritical solvent is added into the extraction tank to extract estrogen from placenta, so as to acquire de-estrogen placenta powder and placenta extract liquor. Under the same condition, the de-estrogen placenta extract liquor and supercritical solvent are added by a preset volume flow ratio into an adsorption tank. The estrogen in the placenta extract liquor is adsorbed by the adsorption tank to obtain de-estrogen placenta extract. It is then eluted with ethanol solution by gradient proportion to obtain purified natural estrogen.
    Type: Application
    Filed: June 10, 2014
    Publication date: October 1, 2015
    Inventors: Zer-Ran YU, Be-Jen WANG, Shu-Mei LIN, Hua-Ching LIN, Ming-Hsi CHUANG, Chu-Ting LIU, Chiu-Ying PENG, Lin-Hsiang CHUANG
  • Publication number: 20150191504
    Abstract: The present invention provides a preparation method of deglycosylated ginsenosides, which uses the supercritical fluid technology to conduct the deglycosylation of ginsenosides extract in supercritical solvent under preset pressure and temperature conditions. Under the same operational conditions, the deglycosylated ginsenosides extract and solvent at supercritical state are input into an adsorption tank at the preset volume flow rate ratio for the adsorption of ginsenosides. Then, the adsorbed ginsenosides are applied with gradient eluent by using the ethanol solution. Finally, the pressure is lowered for the separation and purification of ginsenosides to get the deglycosylated ginsenosides of high concentration.
    Type: Application
    Filed: January 9, 2014
    Publication date: July 9, 2015
    Inventors: SHUEN-AN KANG, ZER-RAN YU
  • Publication number: 20140339157
    Abstract: Methods of controlling a nitrification reaction in a biological nitrogen removal reactor to favor partial nitrification of ammonia to nitrite instead of complete oxidation of ammonia to nitrate are disclosed. In some embodiments, the methods include the following: maintaining a pH in the reactor within a range that promotes growth of ammonia oxidizing bacteria; maintaining a concentration of dissolved oxygen in the reactor within a range that limits the ammonia oxidizing bacteria from completing nitrification; selecting an operational solids retention time within a range suitable for maintaining increasing concentrations of the ammonia oxidizing bacteria in the reactor while reducing concentrations of nitrite oxidizing bacteria in the reactor; and increasing a concentration of free ammonia in the reactor thereby inhibiting growth of the nitrite oxidizing bacteria in the reactor.
    Type: Application
    Filed: November 19, 2013
    Publication date: November 20, 2014
    Inventors: Kartik Chandran, Ran Yu, Joon Ho Ahn
  • Publication number: 20140128582
    Abstract: The present invention provides a continuous preparation method of ginseng ginsenosides and polysaccharides, whereby the ginseng extract liquor and supercritical solvent are poured continuously into a separation tank at 10-30 MPa and 40-60° C. as well as a preset flow rate; so the ginseng extract liquor can be separated in the separation tank to obtain ginseng ginsenosides and polysaccharides at different positions of the separation tank.
    Type: Application
    Filed: November 6, 2012
    Publication date: May 8, 2014
    Inventors: Zer-Ran Yu, Be-Jen Wang
  • Patent number: 8586337
    Abstract: Methods of controlling a nitrification reaction in a biological nitrogen removal reactor to favor partial nitrification of ammonia to nitrite instead of complete oxidation of ammonia to nitrate are disclosed. In some embodiments, the methods include the following: maintaining a pH in the reactor within a range that promotes growth of ammonia oxidizing bacteria; maintaining a concentration of dissolved oxygen in the reactor within a range that limits the ammonia oxidizing bacteria from completing nitrification; selecting an operational solids retention time within a range suitable for maintaining increasing concentrations of the ammonia oxidizing bacteria in the reactor while reducing concentrations of nitrite oxidizing bacteria in the reactor; and increasing a concentration of free ammonia in the reactor thereby inhibiting growth of the nitrite oxidizing bacteria in the reactor.
    Type: Grant
    Filed: October 6, 2008
    Date of Patent: November 19, 2013
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Kartik Chandran, Ran Yu, Joon Ho Ahn
  • Publication number: 20130289300
    Abstract: The present invention provides a method and system for separating linalyl acetate from Lavender essential oil and preparing its derivatives, whereby the supercritical fluid technology is used to feed Lavender essential oil and supercritical solvent into the first separating tank, where linalyl acetate and linalool are separated from Lavender essential oil; then linalyl acetate is conveyed to the second separating tank, where linalyl acetate is separated with wax-containing oily substance to obtain high-concentration linalyl acetate; next linalool and vitamin C solution are conveyed to a reaction tank for esterification synthesis, and the reaction tank is filled with acid resin catalyst to obtain linalool-vitamin C derivative; with this design, it is possible to reduce the nervous tension, and adjust high-concentration linalyl acetate affecting physiological and psychological stress, as well as vitamin C derivative with anti-oxidizing oily fragrance.
    Type: Application
    Filed: April 25, 2012
    Publication date: October 31, 2013
    Inventors: Zer-Ran Yu, Be-Jen Wang