Patents by Inventor Rand M. Posmantur

Rand M. Posmantur has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of modulating microglial activation for the treatment of acute and chronic neurodegenerative disorders
    Patent number: 6545019
    Abstract: The present invention provides methods of modulating or inhibiting microglia activation comprising the administration of a compound capable of inhibiting 5-LOX, FLAP, attenuating degradation of I&kgr;B&agr; or inhibiting nuclear translocation of the NF-&kgr;B active complex for the treatment of Alzheimer's disease, brain ischemia, traumatic brain injury, Parkinson's Disease, Multiple Sclerosis, ALS, subarachnoid hemorrhage or other disorders associated with excessive production of inflammatory mediators in the brain.
    Type: Grant
    Filed: July 5, 2001
    Date of Patent: April 8, 2003
    Assignee: Bristol-Myers Squibb Company
    Inventors: Rand M. Posmantur, Lav Kumar Parvathenani
  • Method of modulating microglial activation for the treatment of acute and chronic neurodegenerative disorders
    Publication number: 20030050322
    Abstract: The present invention provides methods of modulating or inhibiting microglia activation comprising the administration of a compound capable of inhibiting 5-LOX, FLAP, attenuating degradation of I&kgr;B&agr; or inhibiting nuclear translocation of the NF-&kgr;B active complex for the treatment of Alzheimer's disease, brain ischemia, traumatic brain injury, Parkinson's Disease, Multiple Sclerosis, ALS, subarachnoid hemorrhage or other disorders associated with excessive production of inflammatory mediators in the brain.
    Type: Application
    Filed: October 17, 2002
    Publication date: March 13, 2003
    Inventors: Rand M. Posmantur, Lav Kumar Parvathenani
  • Method of modulating microglial activation for the treatment of acute and chronic neurodegenerative disorders
    Publication number: 20030045570
    Abstract: The present invention provides methods of modulating or inhibiting microglia activation comprising the administration of a compound capable of inhibiting 5-LOX, FLAP, attenuating degradation of IKB&agr; or inhibiting nuclear translocation of the NF-KB active complex for the treatment of Alzheimer's disease, brain ischemia, traumatic brain injury, Parkinson's Disease, Multiple Sclerosis, ALS, subarachnoid hemorrhage or other disorders associated with excessive production of inflammatory mediators in the brain.
    Type: Application
    Filed: October 17, 2002
    Publication date: March 6, 2003
    Inventors: Rand M. Posmantur, Lav Kumar Parvathenani
  • Method of modulating microglial activation for the treatment of acute and chronic neurodegenerative disorders
    Publication number: 20030045566
    Abstract: The present invention provides methods of modulating or inhibiting microglia activation comprising the administration of a compound capable of inhibiting 5-LOX, FLAP, attenuating degradation of I&kgr;B&agr; or inhibiting nuclear translocation of the NF-&kgr;B active complex for the treatment of Alzheimer's disease, brain ischemia, traumatic brain injury, Parkinson's Disease, Multiple Sclerosis, ALS, subarachnoid hemorrhage or other disorders associated with excessive production of inflammatory mediators in the brain.
    Type: Application
    Filed: October 21, 2002
    Publication date: March 6, 2003
    Inventors: Rand M. Posmantur, Lav Kumar Parvathenani
  • Method of modulating microglial activation for the treatment of acute and chronic neurodegenerative disorders
    Publication number: 20020022650
    Abstract: The present invention provides methods of modulating or inhibiting microglia activation comprising the administration of a compound capable of inhibiting 5-LOX, FLAP, attenuating degradation of I&kgr;B&agr; or inhibiting nuclear translocation of the NF-&kgr;B active complex for the treatment of Alzheimer's disease, brain ischemia, traumatic brain injury, Parkinson's Disease, Multiple Sclerosis, ALS, subarachnoid hemorrhage or other disorders associated with excessive production of inflammatory mediators in the brain.
    Type: Application
    Filed: July 5, 2001
    Publication date: February 21, 2002
    Inventors: Rand M. Posmantur, Lav Kumar Parvathenani